Clinical Trials Using Fluorine F 18 DASA-23

Clinical trials are research studies that involve people. The clinical trials on this list are studying Fluorine F 18 DASA-23. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • [18F]DASA-23 and PET / MRI Scan in Evaluating Pyruvate Kinase M2 Expression in Patients with Intracranial Tumors or Recurrent Glioblastoma and Healthy Volunteers

    This phase I trial studies how well [18F]DASA-23 and positron emission tomography (PET) / magnetic resonance imaging (MRI) scan work in evaluating pyruvate kinase M2 (PKM2) expression in patients with intracranial tumors or recurrent glioblastoma and healthy volunteers. PKM2 regulates brain tumor metabolism, a key factor in glioblastoma growth. [18F]DASA-23 is a radioactive substance with the ability to monitor PKM2 activity. A PET / MRI scan is a procedure in which a small amount of a radioactive substance, such as [18F]DASA-23, is injected into a vein, and a scanner is used to make detailed, computerized pictures of areas inside the body where the substance is used. Tumor cells usually pick up more of these radioactive substances, allowing them to be found. Giving [18F]DASA-23 with a PET / MRI scan may help doctors evaluate PKM2 expression in healthy volunteers and in participants with intracranial tumors or recurrent glioblastoma.
    Location: Stanford Cancer Institute Palo Alto, Palo Alto, California