Clinical Trials Using Ixabepilone
Clinical trials are research studies that involve people. The clinical trials on this list are studying Ixabepilone. All trials on the list are supported by NCI.
NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.
A Study of Etirinotecan Pegol (NKTR-102) Versus Treatment of Physician's Choice (TPC) in Patients With Metastatic Breast Cancer Who Have Stable Brain Metastases and Have Been Previously Treated With an Anthracycline, a Taxane, and Capecitabine
This is an open-label, randomized, active comparator, multicenter, international Phase 3 study of NKTR-102 versus TPC in patients with metastatic breast cancer who have stable brain metastases and have been previously treated with an anthracycline, a taxane, and capecitabine in either the adjuvant or metastatic setting (prior anthracycline may be omitted if medically appropriate or contraindicated for the patient).
Location: 10 locations
Ixabepilone with or without Bevacizumab in Treating Patients with Recurrent or Refractory Stage I-IV Epithelial Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
This phase II trial studies how well ixabepilone with or without bevacizumab works in treating patients with stage I-IV epithelial ovarian, fallopian tube, or primary peritoneal cancer that has come back or that has not responded to previous treatment. Drugs used in chemotherapy, such as ixabepilone, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Antibodies, such as bevacizumab, interfere with the ability of tumor cells to grow and spread. It is not yet known whether giving ixabepilone with or without bevacizumab may work better in treating ovarian, fallopian tube, or primary peritoneal cancer.
Location: 2 locations