Clinical Trials Using Metronidazole Hydrochloride

Clinical trials are research studies that involve people. The clinical trials on this list are studying Metronidazole Hydrochloride. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • Ciprofloxacin, Metronidazole, and Pembrolizumab before Surgery in Treating Patients with Stage I-II Pancreatic Cancer

    This phase IV trial studies how well ciprofloxacin, metronidazole, and pembrolizumab before surgery work in treating patients with stage I-II pancreatic cancer. Ciprofloxacin and metronidazole are commonly prescribed antibiotics for treating different bacterial infections. They work by decreasing and / or eliminating bacteria in the body, thereby altering patients' microbiome (the organisms in the body). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. The purpose of this study is to see if there is any effect on the cancer after being treated with antibiotics and pembrolizumab and if giving these medications before surgery would improve the outcome of cancer treatment.
    Location: Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York