Clinical Trials Using Oncolytic HSV-1 rRp450

Clinical trials are research studies that involve people. The clinical trials on this list are studying Oncolytic HSV-1 rRp450. All trials on the list are supported by NCI.

NCI’s basic information about clinical trials explains the types and phases of trials and how they are carried out. Clinical trials look at new ways to prevent, detect, or treat disease. You may want to think about taking part in a clinical trial. Talk to your doctor for help in deciding if one is right for you.

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  • Oncolytic HSV-1 rRp450 in Treating Patients with Primary Liver Cancer or Liver Metastases

    This phase I trial studies the side effects and best dose of oncolytic HSV-1 rRp450 in treating patients with primary liver cancer or cancer that has spread from the original tumor to the liver (liver metastases). A virus called herpes simplex virus (HSV)-1, which has been changed in a certain way, may be able to kill tumor cells without damaging normal cells.
    Location: Massachusetts General Hospital Cancer Center, Boston, Massachusetts