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Drug: niraparib tosylate monohydrate
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1.

A Study of Niraparib Maintenance Treatment in Patients With Advanced Ovarian Cancer Following Response on Front-Line Platinum-Based Chemotherapy

Status: Active
Phase: Phase III
Type: Treatment
Age: 18 and over
Trial IDs: PR-30-5017-C, NCI-2016-00574, NCT02655016

2.

Study of Niraparib in Combination With Pembrolizumab (MK-3475) in Patients With Triple-negative Breast Cancer or Ovarian Cancer

Status: Active
Phase: Phase II, Phase I
Type: Treatment
Age: 18 and over
Trial IDs: 3000-PN162-01-001, NCI-2016-00219, NCT02657889

3.

A Study of Niraparib in Patients With Ovarian Cancer Who Have Received Three or Four Previous Chemotherapy Regimens

Status: Active
Phase: Phase II
Type: Treatment
Age: 18 and over
Trial IDs: PR-30-5020-C, NCI-2015-01245, NCT02354586

4.

An Efficacy and Safety Study of Niraparib in Men With Metastatic Castration-Resistant Prostate Cancer and DNA-Repair Anomalies

Status: Temporarily closed
Phase: Phase II
Type: Treatment
Age: 18 and over
Trial IDs: CR108208, NCI-2016-01328, 2016-002057-38, 64091742PCR2001, NCT02854436

5.

ESP1/SARC025 Global Collaboration: A Phase I Study of a Combination of the PARP Inhibitor, Niraparib and Temozolomide or Irinotecan in Patients With Previously Treated, Incurable Ewing Sarcoma

Status: Active
Phase: Phase I
Type: Treatment
Age: 13 and over
Trial IDs: ESP1/SARC025, NCI-2015-01135, NCT02044120

6.

Radium Ra 223 Dichloride and Niraparib in Treating Patients with Hormone- Resistant Prostate Cancer Metastatic to the Bone

Status: Not yet active
Phase: Phase I
Type: Treatment
Age: 18 and over
Trial IDs: 16G.085, NCI-2016-00526, NCT03076203

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