Nivolumab with or without Ipilimumab in Treating Patients with Metastatic Sarcoma That Cannot Be Removed by Surgery

< Back to search results
This clinical trial matches:
Show Search Criteria
Status: Temporarily Closed to Accrual

Description

This randomized phase II trial studies how well nivolumab with or without ipilimumab works in treating patients with sarcoma that has spread from the primary site to other parts of the body or cannot be removed by surgery. Monoclonal antibodies, such as nivolumab and ipilimumab, may block tumor growth in different ways by targeting certain cells. It is not yet known whether nivolumab works better with or without ipilimumab in treating patients with metastatic or unresectable sarcoma.

Eligibility Criteria

Inclusion Criteria

  • PRE-REGISTRATION ELIGIBILITY CRITERIA:
  • Patients must have a formalin-fixed, paraffin-embedded (FFPE) tumor block OR 1 representative hematoxylin and eosin (H&E) and 20 unstained sarcoma tissue slides available for submission to central pathology review; this review is mandatory prior to registration to confirm eligibility
  • REGISTRATION ELIGIBILITY CRITERIA:
  • Patients must have histologically confirmed bone or soft tissue sarcoma by central pathology review * Patients must have histologically confirmed liposarcoma (LPS) (only dedifferentiated and pleomorphic; well differentiated not eligible), undifferentiated pleomorphic sarcoma (UPS)/malignant fibrous histiocytoma (MFH), or gastrointestinal stromal tumor (GIST)
  • Measurable disease
  • Locally advanced/unresectable or metastatic disease
  • >= 1 prior systemic therapy for sarcoma, including adjuvant systemic therapy
  • No prior therapy with ipilimumab or nivolumab, or any agent targeting programmed cell death 1 (PD-1), PD-L1 or cytotoxic T-lymphocyte-associated protein 4 (CTLA-4)
  • No treatment with biologic therapy, immunotherapy, chemotherapy, investigational agent for malignancy, or radiation =< 28 days before study registration; no treatment with nitrosourea or mitomycin =< 42 days before study registration; for GIST, tyrosine kinase inhibitor can be continued for up to 3 days prior to initiation of study treatment
  • Patients should have resolution of any toxic effects of prior therapy (except alopecia) to NCI CTCAE, version 4.0, grade 1 or less
  • No history of the following: * Active known or suspected autoimmune disease * Patients with human immunodeficiency virus (HIV) are eligible if the lymphocytes > 350 cluster of differentiation (CD)4+ cells and no detectable viral load * Symptomatic, untreated, or uncontrolled brain metastases present * Active autoimmune colitis * Autoimmune panhypopituitarism * Autoimmune adrenal insufficiency * Known active hepatitis B or C ** Hepatitis B can be defined as: *** Hepatitis B surface antigen (HBsAg) > 6 months *** Serum hepatitis B virus (HBV) deoxyribonucleic acid (DNA) 20,000 IU/ml (105 copies/ml), lower values 2,000-20,000 IU/ml (104-105 copies/ml) are often seen in hepatitis B e antigen (HBeAg)-negative chronic hepatitis B *** Persistent or intermittent elevation in alanine aminotransferase (ALT)/alanine aminotransferase (AST) levels *** Liver biopsy showing chronic hepatitis with moderate or severe necroinflammation ** Hepatitis C can be defined as: *** Hepatitis C antibody (Ab) positive *** Presence of hepatitis C virus (HCV) ribonucleic acid (RNA) * Known active pulmonary disease with hypoxia defined as: ** Oxygen saturation < 85% on room air or ** Oxygen saturation < 88% despite supplemental oxygen
  • No systemic treatment with either corticosteroids (> 10 mg daily prednisone equivalents) or other immunosuppressive medications within 14 days of registration
  • Not pregnant and not nursing; for women of childbearing potential only, a negative pregnancy test done =< 7 days prior to registration is required
  • Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
  • Absolute neutrophil count (ANC) >= 1,500/mm^3
  • Platelet count >= 100,000/mm^3
  • Creatinine =< 1.5 x upper limit of normal (ULN) OR calculated (calc.) creatinine clearance > 45 mL/min using the lean body mass formula only
  • Total bilirubin =< 1.5 x upper limit of normal (ULN) in absence of Gilbert disease (total bilirubin =< 3 x ULN with Gilbert); also, if hyperbilirubinemia is clearly attributed to liver metastases total bilirubin =< 3 x ULN is permitted
  • AST/ALT =< 3 x upper limit of normal (ULN)
  • Thyroid stimulating hormone (TSH) within normal limits (WNL); supplementation is acceptable to achieve a TSH WNL; in patients with abnormal TSH if free T4 is normal and patient is clinically euthyroid, patient is eligible
  • Re-registration Eligibility Criteria (for patients who crossover from arm 1 nivolumab alone to dual agent nivolumab and ipilimumab upon progression)
  • Re-registration: measurable disease
  • Re-registration: locally advanced/unresectable or metastatic disease
  • Patient MUST have had progressive disease (radiographic or clinical) while on arm 1 single agent nivolumab while registered to A091401
  • Patients removed from any immunotherapy for reasons other than progressive disease, including arm 1 single agent nivolumab of A091401, are NOT eligible for re-registration
  • Patients must have completed a minimum of 10 weeks of single agent nivolumab on arm 1 of A091401 to be eligible for re-registration
  • Patients must have completed study drug on arm 1 of A091401 (i.e., last dose of nivolumab) =< 12 months of re-registration to crossover dual agent therapy
  • No treatment with immunotherapy =< 21 days before re-registration; no treatment with biologic therapy, chemotherapy, investigational agent for malignancy, or radiation =< 28 days before re-registration; no treatment with nitrosourea or mitomycin =< 42 days before re-registration
  • Patients should have resolution of any toxic effects of prior therapy (except fatigue and alopecia) to NCI CTCAE, version 4.0, grade 1 or less, including immune toxicity
  • No systemic treatment with either corticosteroids (> 10 mg daily prednisone equivalents) or other immunosuppressive medications within 14 days of re-registration
  • Not pregnant and not nursing; therefore, for women of childbearing potential only, a negative pregnancy test done =< 7 days prior to re-registration is required
  • ECOG performance status 0 or 1
  • Re-registration: ANC >= 1,500/mm^3
  • Re-registration: platelet count >= 100,000/mm^3
  • Re-registration: creatinine =< 1.5 ULN OR calc. creatinine clearance > 45 mL/min (using lean body mass formula only)
  • Re-registration: total bilirubin =< 1.5 x ULN in absence of Gilbert disease (total bilirubin =< 3 x ULN with Gilbert); if hyperbilirubinemia is clearly attributed to liver metastases, total bilirubin =< 3 x ULN is permitted
  • Re-registration: AST/ALT =< 3 x ULN
  • Re-registration: TSH WNL; supplementation is acceptable to achieve a TSH WNL; in patients with abnormal TSH, if free T4 is normal and patient is clinically euthyroid, patient is eligible

Locations & Contacts

Alaska

Anchorage
Alaska Breast Care and Surgery LLC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Alaska Oncology and Hematology LLC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Alaska Regional Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 907-264-2933
Alaska Women's Cancer Care
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Anchorage Associates in Radiation Medicine
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Anchorage Oncology Centre
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Anchorage Radiation Therapy Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Katmai Oncology Group
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org
Providence Alaska Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 907-212-6871 Email: AKPAMC.OncologyResearchSupport@providence.org

Arkansas

Hot Springs
CHI Saint Vincent Cancer Center Hot Springs
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org

California

Antioch
Kaiser Permanente-Deer Valley Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Arroyo Grande
PCR Oncology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Auburn
Sutter Auburn Faith Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Sutter Cancer Centers Radiation Oncology Services-Auburn
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Berkeley
Alta Bates Summit Medical Center-Herrick Campus
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Burbank
Providence Saint Joseph Medical Center / Disney Family Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 818-847-4793 Email: Madonna.Johnson@providence.org
Burlingame
Mills-Peninsula Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Cameron Park
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Castro Valley
Eden Hospital Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 510-537-1234
Davis
Sutter Davis Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Fremont
Kaiser Permanente-Fremont
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Palo Alto Medical Foundation-Fremont
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Fresno
Kaiser Permanente-Fresno
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Loma Linda
Loma Linda University Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 909-558-3375
Modesto
Kaiser Permanente-Modesto
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Memorial Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Mountain View
Palo Alto Medical Foundation-Camino Division
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Palo Alto Medical Foundation-Gynecologic Oncology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Novato
Sutter Cancer Research Consortium
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Oakland
Kaiser Permanente-Oakland
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Palo Alto
Palo Alto Medical Foundation Health Care
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Redwood City
Kaiser Permanente-Redwood City
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Richmond
Kaiser Permanente-Richmond
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Roseville
Kaiser Permanente-Roseville
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Sutter Cancer Centers Radiation Oncology Services-Roseville
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Sutter Roseville Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Sacramento
Kaiser Permanente - Sacramento
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Kaiser Permanente Downtown Commons
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691
Kaiser Permanente-South Sacramento
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Sutter Medical Center Sacramento
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
San Francisco
California Pacific Medical Center-Pacific Campus
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Kaiser Permanente-San Francisco
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
San Jose
Kaiser Permanente-Santa Teresa-San Jose
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
San Leandro
Kaiser Permanente San Leandro
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
San Rafael
Kaiser Permanente-San Rafael
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Kaiser San Rafael-Gallinas
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Santa Clara
Kaiser Permanente Medical Center - Santa Clara
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Santa Cruz
Palo Alto Medical Foundation-Santa Cruz
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Santa Rosa
Kaiser Permanente-Santa Rosa
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Sutter Pacific Medical Foundation
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
South San Francisco
Kaiser Permanente-South San Francisco
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Stockton
Kaiser Permanente-Stockton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Sunnyvale
Palo Alto Medical Foundation-Sunnyvale
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Vacaville
Kaiser Permanente Medical Center-Vacaville
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Vallejo
Kaiser Permanente-Vallejo
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org
Sutter Solano Medical Center / Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 415-209-2686 Email: bernicl@sutterhealth.org
Walnut Creek
Kaiser Permanente-Walnut Creek
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-642-4691 Email: Kpoct@kp.org

Colorado

Aurora
Rocky Mountain Cancer Centers-Aurora
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
The Medical Center of Aurora
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Boulder
Boulder Community Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: jbloomfield@co-cancerresearch.org
Rocky Mountain Cancer Centers-Boulder
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Colorado Springs
Penrose-Saint Francis Healthcare
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Rocky Mountain Cancer Centers-Penrose
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Denver
Colorado Blood Cancer Institute
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Denver Health Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Porter Adventist Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Presbyterian - Saint Lukes Medical Center - Health One
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Midtown
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rocky Mountain Cancer Centers-Rose
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Rose Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
The Women's Imaging Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Durango
Mercy Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Southwest Oncology PC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Englewood
Comprehensive Cancer Care and Research Institute of Colorado LLC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Swedish Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Golden
Mountain Blue Cancer Care Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
National Jewish Health-Western Hematology Oncology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: glicht@co-cancerresearch.org
Grand Junction
Saint Mary's Hospital and Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Greeley
North Colorado Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Greenwood Village
Rocky Mountain Cancer Centers-Greenwood Village
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Lafayette
Good Samaritan Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-673-1622
Lakewood
Rocky Mountain Cancer Centers-Lakewood
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Saint Anthony Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Littleton
Littleton Adventist Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Rocky Mountain Cancer Centers-Littleton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Lone Tree
Rocky Mountain Cancer Centers-Sky Ridge
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Sky Ridge Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Longmont
Longmont United Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Rocky Mountain Cancer Centers-Longmont
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Loveland
McKee Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Parker
Parker Adventist Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Rocky Mountain Cancer Centers-Parker
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Pueblo
Rocky Mountain Cancer Centers - Pueblo
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Saint Mary Corwin Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Thornton
Rocky Mountain Cancer Centers-Thornton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Wheat Ridge
SCL Health Lutheran Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org

Connecticut

Hartford
Smilow Cancer Hospital Care Center at Saint Francis
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 203-785-5702 Email: canceranswers@yale.edu
Norwich
Eastern Connecticut Hematology and Oncology Associates
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 860-886-8362

Delaware

Lewes
Beebe Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-645-3770 Email: Dmiskin@Beebehealthcare.org
Newark
Christiana Care Health System-Christiana Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-623-4450 Email: KDempsey@christianacare.org
Christiana Gynecologic Oncology LLC
Status: Temporarily closed to accrual
Contact: Gregory Andrew Masters
Phone: 302-733-6227
Delaware Clinical and Laboratory Physicians PA
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-623-4450 Email: KDempsey@christianacare.org
Helen F Graham Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-623-4450 Email: KDempsey@christianacare.org
Medical Oncology Hematology Consultants PA
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-623-4450 Email: KDempsey@christianacare.org
Regional Hematology and Oncology PA
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-623-4450 Email: KDempsey@christianacare.org
Rehoboth Beach
Beebe Health Campus
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-645-3100 Email: Dmiskin@Beebehealthcare.org
Seaford
Nanticoke Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-645-3100 Email: Dmiskin@Beebehealthcare.org
Wilmington
Christiana Care Health System-Wilmington Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-623-4450 Email: KDempsey@christianacare.org

District of Columbia

Washington
MedStar Georgetown University Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 202-444-2223
MedStar Washington Hospital Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 202-877-8839
Sibley Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 202-243-2373 Email: jquiver1@jhmi.edu

Florida

Aventura
Mount Sinai Comprehensive Cancer Center at Aventura
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Deerfield Beach
UM Sylvester Comprehensive Cancer Center at Deerfield Beach
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 305-243-2647
Fort Lauderdale
Holy Cross Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 954-267-7750
Jacksonville
Baptist MD Anderson Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 904-202-7051
Miami
University of Miami Miller School of Medicine-Sylvester Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 305-243-2647
Miami Beach
Mount Sinai Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 305-674-2625 Email: info@msccop.com
Plantation
UM Sylvester Comprehensive Cancer Center at Plantation
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 305-243-2647

Georgia

Savannah
Lewis Cancer and Research Pavilion at Saint Joseph's / Candler
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 888-823-5923 Email: ctsucontact@westat.com
Low Country Cancer Care Associates PC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 912-692-2000
Memorial Health University Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 912-350-7887 Email: clayter1@memorialhealth.com
Summit Cancer Care-Candler
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 888-823-5923 Email: ctsucontact@westat.com
Summit Cancer Care-Memorial
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 912-350-7887 Email: clayter1@memorialhealth.com

Hawaii

Aiea
Hawaii Oncology Inc-Pali Momi
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-487-7447
Pali Momi Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-486-6000
The Cancer Center of Hawaii-Pali Momi
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-678-9000
Honolulu
Hawaii Cancer Care Inc-Liliha
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-536-4888
Hawaii Cancer Care Inc-POB II
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-524-6115
Hawaii Oncology Inc-Kuakini
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-531-8521
Hawaii Oncology Inc-POB I
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-532-0315
Island Urology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-536-2306 Email: virginia@cc.hawaii.edu
Kaiser Permanente Moanalua Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-432-5195 Email: shelley.a.clark@kp.org
Kapiolani Medical Center for Women and Children
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-983-6090
Kuakini Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-547-9816
Queen's Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Straub Clinic and Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-522-4333
The Cancer Center of Hawaii-Liliha
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-547-6881
University of Hawaii Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-586-2979
Lihue
Wilcox Memorial Hospital and Kauai Medical Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 808-535-7960

Idaho

Boise
Saint Alphonsus Cancer Care Center-Boise
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint Luke's Mountain States Tumor Institute
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Caldwell
Saint Alphonsus Cancer Care Center-Caldwell
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Coeur D'Alene
Kootenai Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Emmett
Walter Knox Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Fruitland
Saint Luke's Mountain States Tumor Institute - Fruitland
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Meridian
Idaho Urologic Institute-Meridian
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint Luke's Mountain States Tumor Institute - Meridian
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Nampa
Saint Alphonsus Medical Center-Nampa
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint Luke's Mountain States Tumor Institute - Nampa
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Post Falls
Kootenai Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Sandpoint
Kootenai Cancer Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Twin Falls
Saint Luke's Mountain States Tumor Institute-Twin Falls
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org

Illinois

Aurora
Rush - Copley Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com
Bloomington
Illinois CancerCare-Bloomington
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Canton
Illinois CancerCare-Canton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Carbondale
Memorial Hospital of Carbondale
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 618-457-5200 Email: clinical.research@sih.net
Carterville
SIH Cancer Institute
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 618-985-3333 Email: clinical.research@sih.net
Carthage
Illinois CancerCare-Carthage
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Centralia
Centralia Oncology Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 217-876-4740 Email: rhamrick@dmhhs.org
Chicago
Rush University Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 312-942-5498 Email: clinical_trials@rush.edu
Danville
Carle on Vermilion
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-446-5532 Email: Research@carle.com
Decatur
Cancer Care Specialists of Illinois - Decatur
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 217-876-4740 Email: rhamrick@dmhhs.org
Decatur Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 217-876-4740 Email: rhamrick@dmhhs.org
Effingham
Carle Physician Group-Effingham
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-446-5532 Email: Research@carle.com
Crossroads Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 217-876-4740 Email: rhamrick@dmhhs.org
Eureka
Illinois CancerCare-Eureka
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Evanston
NorthShore University HealthSystem-Evanston Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 847-570-2109
Galesburg
Illinois CancerCare-Galesburg
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Western Illinois Cancer Treatment Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-344-2831
Glenview
NorthShore University HealthSystem-Glenbrook Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 847-570-2109
Highland Park
NorthShore University HealthSystem-Highland Park Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 847-570-2109
Kewanee
Illinois CancerCare-Kewanee Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Macomb
Illinois CancerCare-Macomb
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Mattoon
Carle Physician Group-Mattoon / Charleston
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-446-5532 Email: Research@carle.com
Maywood
Loyola University Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 708-226-4357
Mount Vernon
Good Samaritan Regional Health Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 618-242-4600
Ottawa
Illinois CancerCare-Ottawa Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Radiation Oncology of Northern Illinois
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Pekin
Illinois CancerCare-Pekin
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Peoria
Illinois CancerCare-Peoria
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Methodist Medical Center of Illinois
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
OSF Saint Francis Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
OSF Saint Francis Radiation Oncology at Peoria Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Peru
Illinois CancerCare-Peru
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Valley Radiation Oncology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 815-664-4141
Princeton
Illinois CancerCare-Princeton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 309-243-3605 Email: andersonj@illinoiscancercare.com
Skokie
North Shore Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 888-823-5923 Email: ctsucontact@westat.com
Springfield
Memorial Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 217-788-3528
Southern Illinois University School of Medicine
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 217-545-7929
Springfield Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-444-7541
Swansea
Cancer Care Specialists of Illinois-Swansea
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 217-876-4740 Email: rhamrick@dmhhs.org
Southwest Illinois Health Services LLP
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 618-236-1000 Email: lynns@thecancercenter.com
Urbana
Carle Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-446-5532 Email: Research@carle.com
The Carle Foundation Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-446-5532 Email: Research@carle.com
Yorkville
Rush-Copley Healthcare Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 630-978-6212 Email: Cancer.Research@rushcopley.com

Indiana

Evansville
Deaconess Clinic Downtown
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-654-0311 Email: Research@Deaconess.com
Fort Wayne
Parkview Hospital Randallia
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 260-373-8888 Email: parkviewresearch@parkview.com
Michigan City
Franciscan Saint Anthony Health-Michigan City
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-931-3322
Woodland Cancer Care Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Mishawaka
Memorial Regional Cancer Center Day Road
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Newburgh
Chancellor Center for Oncology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-654-0311 Email: Research@Deaconess.com
South Bend
Memorial Hospital of South Bend
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-284-7370

Iowa

Ames
Mary Greeley Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-239-2621
McFarland Clinic PC - Ames
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-239-2621
Boone
McFarland Clinic PC-Boone
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-239-2621
Clive
Medical Oncology and Hematology Associates-West Des Moines
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Mercy Cancer Center-West Lakes
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Council Bluffs
Alegent Health Mercy Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Creston
Greater Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Des Moines
Broadlawns Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-282-2200
Iowa Lutheran Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-241-8704
Iowa Methodist Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-241-6727
Medical Oncology and Hematology Associates-Des Moines
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-282-2921
Medical Oncology and Hematology Associates-Laurel
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Mercy Medical Center - Des Moines
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Fort Dodge
McFarland Clinic PC-Trinity Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-239-2621
Trinity Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-574-8302
Iowa City
University of Iowa / Holden Comprehensive Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-237-1225
Jefferson
McFarland Clinic PC-Jefferson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-239-2621
Marshalltown
McFarland Clinic PC-Marshalltown
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-239-2621
West Des Moines
Mercy Medical Center-West Lakes
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Methodist West Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 515-343-1000

Kansas

Chanute
Cancer Center of Kansas - Chanute
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Dodge City
Cancer Center of Kansas - Dodge City
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
El Dorado
Cancer Center of Kansas - El Dorado
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Fort Scott
Cancer Center of Kansas - Fort Scott
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Garden City
Central Care Cancer Center - Garden City
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 913-948-5588 Email: aroland@kccop.org
Great Bend
Central Care Cancer Center - Great Bend
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 913-948-5588 Email: aroland@kccop.org
Independence
Cancer Center of Kansas-Independence
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Kingman
Cancer Center of Kansas-Kingman
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Lawrence
Lawrence Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Lenexa
Kansas Institute of Medicine Cancer and Blood Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 913-948-5588 Email: aroland@kccop.org
Minimally Invasive Surgery Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 913-948-5588 Email: aroland@kccop.org
Liberal
Cancer Center of Kansas-Liberal
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Manhattan
Cancer Center of Kansas-Manhattan
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5784 Email: Keisha.humphries@ascension.org
McPherson
Cancer Center of Kansas - McPherson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Newton
Cancer Center of Kansas - Newton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Overland Park
Menorah Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 913-948-5588 Email: aroland@kccop.org
Parsons
Cancer Center of Kansas - Parsons
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Pratt
Cancer Center of Kansas - Pratt
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Salina
Cancer Center of Kansas - Salina
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Wellington
Cancer Center of Kansas - Wellington
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Wichita
Associates In Womens Health
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Cancer Center of Kansas - Wichita
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Cancer Center of Kansas-Wichita Medical Arts Tower
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org
Via Christi Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-362-0070 Email: Keisha.humphries@ascension.org
Winfield
Cancer Center of Kansas - Winfield
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 316-268-5374 Email: Keisha.humphries@ascension.org

Kentucky

Bardstown
Flaget Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Corbin
Commonwealth Cancer Center-Corbin
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Lexington
Saint Joseph Hospital East
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Saint Joseph Radiation Oncology Resource Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
London
Saint Joseph London
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Louisville
Jewish Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Jewish Hospital Medical Center Northeast
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Saints Mary and Elizabeth Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Shepherdsville
Jewish Hospital Medical Center South
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org

Louisiana

Baton Rouge
Medical Center of Baton Rouge
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 225-761-5346 Email: Camille.Beck@Ochsner.org
Ochsner Health Center-Summa
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 225-761-5346 Email: Camille.Beck@Ochsner.org
Kenner
Ochsner Medical Center Kenner
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 504-464-8314 Email: cris.molina@ochsner.org
New Orleans
Ochsner Medical Center Jefferson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 504-703-8712 Email: Gregory.Johnstone@ochsner.org

Maryland

Baltimore
Johns Hopkins University / Sidney Kimmel Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 410-955-8804 Email: jhcccro@jhmi.edu
MedStar Franklin Square Medical Center / Weinberg Cancer Institute
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 443-777-7364

Massachusetts

Boston
Dana-Farber Cancer Institute
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-442-3324
Massachusetts General Hospital Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 877-726-5130
Springfield
Mercy Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 413-748-9234

Michigan

Ann Arbor
Saint Joseph Mercy Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
University of Michigan Comprehensive Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-865-1125
Brighton
IHA Hematology Oncology Consultants-Brighton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint Joseph Mercy Brighton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Canton
IHA Hematology Oncology Consultants-Canton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint Joseph Mercy Canton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Caro
Caro Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Chelsea
IHA Hematology Oncology Consultants-Chelsea
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint Joseph Mercy Chelsea
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Clarkston
Hematology Oncology Consultants-Clarkston
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Newland Medical Associates-Clarkston
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Dearborn
Beaumont Hospital-Dearborn
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 248-551-7695
Detroit
Ascension Saint John Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
East China
Great Lakes Cancer Management Specialists-Doctors Park
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Flint
Genesee Cancer and Blood Disease Treatment Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Genesee Hematology Oncology PC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Genesys Hurley Cancer Institute
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Hurley Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Gorsse Pointe Woods
Lymphoma Clinic of Michigan
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Grosse Pointe Woods
Great Lakes Cancer Management Specialists-Van Elslander Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Michigan Breast Specialists-Grosse Pointe Woods
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Jackson
Allegiance Health
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 517-788-4800
Lansing
Sparrow Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Livonia
Hope Cancer Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint Mary Mercy Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Macomb Township
Great Lakes Cancer Management Specialists-Macomb Medical Campus
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Michigan Breast Specialists-Macomb Township
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Marlette
Saint Mary's Oncology / Hematology Associates of Marlette
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 989-343-2487
Pontiac
21st Century Oncology-Pontiac
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Hope Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Newland Medical Associates-Pontiac
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint Joseph Mercy Oakland
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Port Huron
Huron Medical Center PC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Lake Huron Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Rochester Hills
Great Lakes Cancer Management Specialists-Rochester Hills
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saginaw
Oncology Hematology Associates of Saginaw Valley PC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint Mary's of Michigan
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Sterling Heights
Bhadresh Nayak MD PC-Sterling Heights
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Tawas City
Saint Joseph Health System-Tawas City
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Warren
Advanced Breast Care Center PLLC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Bhadresh Nayak MD PC-Warren
Status: Active
Contact: Tareq Al Baghdadi
Phone: 734-712-3671
Great Lakes Cancer Management Specialists-Macomb Professional Building
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Macomb Hematology Oncology PC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Michigan Breast Specialists-Warren
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Saint John Macomb-Oakland Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
West Branch
Saint Mary's Oncology / Hematology Associates of West Branch
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 989-343-2487
Ypsilanti
Huron Gastroenterology PC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
IHA Hematology Oncology Consultants-Ann Arbor
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org

Minnesota

Bemidji
Sanford Clinic North-Bemidgi
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 218-333-5000
Brainerd
Essentia Health Saint Joseph's Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Burnsville
Fairview Ridges Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Coon Rapids
Mercy Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Deer River
Essentia Health - Deer River Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 218-786-3308
Detroit Lakes
Essentia Health Saint Mary's - Detroit Lakes Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Duluth
Essentia Health Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 218-786-3308 Email: CancerTrials@EssentiaHealth.org
Essentia Health Saint Mary's Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 888-203-7267
Miller-Dwan Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 218-786-3308 Email: CancerTrials@EssentiaHealth.org
Edina
Fairview-Southdale Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Fergus Falls
Lake Region Healthcare Corporation-Cancer Care
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 218-786-3308 Email: CancerTrials@EssentiaHealth.org
Fosston
Essentia Health - Fosston
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 701-364-6272
Fridley
Unity Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Hibbing
Essentia Health Hibbing Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Maple Grove
Fairview Maple Grove Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Maplewood
Minnesota Oncology Hematology PA-Maplewood
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Saint John's Hospital - Healtheast
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Minneapolis
Abbott-Northwestern Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Health Partners Inc
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Hennepin County Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
New Ulm
New Ulm Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Park Rapids
Essentia Health - Park Rapids
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 701-364-6272
Robbinsdale
North Memorial Medical Health Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Saint Louis Park
Park Nicollet Clinic - Saint Louis Park
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Saint Paul
Regions Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
United Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Sandstone
Essentia Health Sandstone
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 701-364-6272
Shakopee
Saint Francis Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Stillwater
Lakeview Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Thief River Falls
Sanford Thief River Falls Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 605-312-3320
Virginia
Essentia Health Virginia Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 218-786-3308 Email: CancerTrials@EssentiaHealth.org
Waconia
Ridgeview Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Willmar
Rice Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Woodbury
Minnesota Oncology Hematology PA-Woodbury
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Worthington
Sanford Cancer Center Worthington
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 605-312-3320
Wyoming
Fairview Lakes Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com

Missouri

Bolivar
Central Care Cancer Center - Bolivar
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 913-948-5588 Email: aroland@kccop.org
Bonne Terre
Parkland Health Center-Bonne Terre
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 314-996-5569
Branson
Cox Cancer Center Branson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 417-269-4520
Cape Girardeau
Saint Francis Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 573-334-2230 Email: sfmc@sfmc.net
Southeast Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 573-651-5550
Chesterfield
Saint Luke's Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Independence
Centerpoint Medical Center LLC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 913-948-5588 Email: aroland@kccop.org
Jefferson City
Capital Region Southwest Campus
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 573-632-4814 Email: swooden@mail.crmc.org
Joplin
Freeman Health System
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 417-347-4030 Email: LJCrockett@freemanhealth.com
Mercy Hospital Joplin
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 417-556-3074 Email: esmeralda.carrillo@mercy.net
Kansas City
Research Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 913-948-5588 Email: aroland@kccop.org
Rolla
Delbert Day Cancer Institute at PCRMC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 573-458-7504 Email: jrichards@research.pcrmc.com
Mercy Clinic-Rolla-Cancer and Hematology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 573-458-7504 Email: jrichards@research.pcrmc.com
Saint Joseph
Heartland Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 816-271-7937 Email: linda.schumacher@mymlc.com
Saint Louis
Mercy Hospital Saint Louis
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 314-251-6770
Missouri Baptist Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 314-996-5569
Saint Louis Cancer and Breast Institute-South City
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 314-353-1870
Siteman Cancer Center-South County
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Washington University School of Medicine
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-600-3606 Email: info@siteman.wustl.edu
Sainte Genevieve
Sainte Genevieve County Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 314-996-5569
Springfield
CoxHealth South Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 417-269-4520
Mercy Hospital Springfield
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 417-269-4520
Sullivan
Missouri Baptist Sullivan Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 314-996-5569
Sunset Hills
Missouri Baptist Outpatient Center-Sunset Hills
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 314-996-5569

Montana

Billings
Billings Clinic Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-996-2663 Email: research@billingsclinic.org
Saint Vincent Frontier Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-648-6274
Saint Vincent Healthcare
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Bozeman
Bozeman Deaconess Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Butte
Saint James Community Hospital and Cancer Treatment Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-723-2621
Great Falls
Benefis Healthcare- Sletten Cancer Institute
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Helena
Saint Peter's Community Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Kalispell
Kalispell Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Missoula
Community Medical Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-969-6060 Email: mccinfo@mtcancer.org
Saint Patrick Hospital - Community Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-327-3118 Email: amy.hanneman@providence.org

Nebraska

Grand Island
CHI Health Saint Francis
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Kearney
CHI Health Good Samaritan
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Heartland Hematology and Oncology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Lincoln
Saint Elizabeth Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Omaha
Alegent Health Bergan Mercy Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Alegent Health Immanuel Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Alegent Health Lakeside Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Creighton University Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Hematology and Oncology Consultants PC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Nebraska Methodist Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 402-354-5144
Papillion
Midlands Community Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org

Nevada

Carson City
Carson Tahoe Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Henderson
21st Century Oncology-Henderson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Cancer and Blood Specialists-Henderson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Comprehensive Cancer Centers of Nevada - Henderson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Comprehensive Cancer Centers of Nevada-Horizon Ridge
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Las Vegas Cancer Center-Henderson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Nevada Cancer Specialists-Saint Rose
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Las Vegas
21st Century Oncology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
21st Century Oncology-Fort Apache
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
21st Century Oncology-Vegas Tenaya
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Ann M Wierman MD LTD
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Cancer and Blood Specialists-Shadow
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Cancer and Blood Specialists-Tenaya
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Cancer Therapy and Integrative Medicine
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Comprehensive Cancer Centers of Nevada
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Comprehensive Cancer Centers of Nevada - Central Valley
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Comprehensive Cancer Centers of Nevada - Northwest
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Comprehensive Cancer Centers of Nevada-Summerlin
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Desert West Surgery
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
HealthCare Partners Medical Group Oncology / Hematology-Centennial Hills
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
HealthCare Partners Medical Group Oncology / Hematology-Maryland Parkway
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
HealthCare Partners Medical Group Oncology / Hematology-San Martin
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
HealthCare Partners Medical Group Oncology / Hematology-Tenaya
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Las Vegas Cancer Center-Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Nevada Cancer Specialists?Oakey
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Nevada Cancer Specialists-Fort Apache
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Nevada Cancer Specialists-Tenaya
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Radiation Oncology Centers of Nevada Central
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Radiation Oncology Centers of Nevada Southeast
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Summerlin Hospital Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
University Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
University Medical Center of Southern Nevada
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Pahrump
Hope Cancer Care of Nevada-Pahrump
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Reno
Radiation Oncology Associates
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Renown Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 702-384-0013 Email: research@sncrf.org
Saint Mary's Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org

New Jersey

Brick
Ocean Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 732-206-8384
Camden
Cooper Hospital University Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 856-325-6757
Hackensack
Hackensack University Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 201-996-2879
Holmdel
Bayshore Community Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Manahawkin
Southern Ocean County Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 609-978-3429
Mount Laurel
Cooper CyberKnife Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 888-823-5923 Email: ctsucontact@westat.com
Neptune
Jersey Shore Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 732-776-4240
Red Bank
Riverview Medical Center / Booker Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 732-530-2382
Voorhees
MD Anderson Cancer Center at Cooper-Voorhees
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 856-325-6757

New Mexico

Albuquerque
New Mexico Oncology Hematology Consultants
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 505-272-0530 Email: CLee@nmcca.org
University of New Mexico Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 505-925-0366 Email: LByatt@nmcca.org
Las Cruces
Memorial Medical Center - Las Cruces
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 575-556-6545 Email: Kim.Hoffman@lpnt.net

New York

New York
Columbia University / Herbert Irving Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 212-305-6361 Email: nr2616@cumc.columbia.edu
Memorial Sloan Kettering Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 212-639-7592

North Carolina

Asheville
Asheville Hematology-Oncology Associates
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 828-681-2917 Email: daniel.figueroa@ahss.org
Clinton
Southeastern Medical Oncology Center-Clinton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 919-587-9077 Email: ecooke@cancersmoc.com
Clyde
Haywood Infusion Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Goldsboro
Southeastern Medical Oncology Center-Goldsboro
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 919-587-9077 Email: ecooke@cancersmoc.com
Wayne Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 919-731-6687 Email: ecooke@cancersmoc.com
Hendersonville
Hendersonville Hematology and Oncology at Pardee
Status: Temporarily closed to accrual
Contact: James Earl Radford
Phone: 828-696-4716
Margaret R Pardee Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 828-696-4716 Email: karen.morris@unchealth.unc.edu
Park Ridge Health
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 828-681-2917 Email: Daniel.Figueroa@ahss.org
Jacksonville
Onslow Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 910-353-0824 Email: ecooke@cancersmoc.com
Southeastern Medical Oncology Center-Jacksonville
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 910-353-0824 Email: ecooke@cancersmoc.com
Kinston
Vidant Oncology-Kinston
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 252-559-2201 Email: Carla.Zimmerman@vidanthealth.com
Wilson
Southeastern Medical Oncology Center-Wilson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-849-0203

North Dakota

Bismarck
Sanford Bismarck Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 701-323-5760 Email: tamara.fischer@sanfordhealth.org
Fargo
Essentia Health Cancer Center-South University Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 218-786-3308 Email: CancerTrials@EssentiaHealth.org
Roger Maris Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 701-234-6161
Sanford Broadway Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-437-4010
Sanford Clinic North-Fargo
Status: Temporarily closed to accrual
Contact: Preston D. Steen
Phone: 712-252-0088
Sanford South University Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 701-234-6161
Jamestown
Essentia Health - Jamestown Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 701-364-6272

Ohio

Beachwood
UHHS-Chagrin Highlands Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Chardon
Geauga Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Cincinnati
Bethesda North Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Good Samaritan Hospital - Cincinnati
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
TriHealth Cancer Institute-Anderson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
TriHealth Cancer Institute-Westside
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Cleveland
Case Western Reserve University
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Columbus
Ohio State University Comprehensive Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-293-5066 Email: Jamesline@osumc.edu
Elyria
Hematology Oncology Center Incorporated
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 888-823-5923 Email: ctsucontact@westat.com
Mercy Cancer Center-Elyria
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Mayfield Heights
Ireland Cancer Center Landerbrook Health Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Mentor
Lake University Ireland Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Middleburg Heights
Southwest General Health Center Ireland Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Parma
University Hospitals Parma Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Sandusky
Ireland Cancer Center at Firelands Regional Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Wadsworth
University Hospitals Sharon Health Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
Westlake
UH Seidman Cancer Center at Saint John Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org
UHHS-Westlake Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-641-2422 Email: CTUReferral@UHhospitals.org

Oklahoma

Oklahoma City
Mercy Hospital Oklahoma City
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 405-752-3402

Oregon

Baker City
Saint Alphonsus Medical Center-Baker City
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Bend
Saint Charles Health System
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 541-706-2909 Email: nosall@stcharleshealthcare.org
Clackamas
Clackamas Radiation Oncology Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Providence Oncology and Hematology Care Southeast
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Coos Bay
Bay Area Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 541-269-8392 Email: cherie.cox@bayareahospital.org
Newberg
Providence Newberg Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Ontario
Saint Alphonsus Medical Center-Ontario
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Oregon City
Providence Willamette Falls Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Portland
Kaiser Permanente Northwest
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 503-335-2400 Email: information@kpchr.org
Providence Portland Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Providence Saint Vincent Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 503-215-2614 Email: CanRsrchStudies@providence.org
Redmond
Saint Charles Health System-Redmond
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 541-706-2909

Pennsylvania

Allentown
Lehigh Valley Hospital-Cedar Crest
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Bethlehem
Lehigh Valley Hospital - Muhlenberg
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 734-712-3671 Email: stephanie.couch@stjoeshealth.org
Chadds Ford
Christiana Care Health System-Concord Health Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 302-623-4450 Email: KDempsey@christianacare.org
Danville
Geisinger Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 570-271-5251 Email: HemonCCTrials@geisinger.edu
Hazleton
Geisinger Medical Center-Cancer Center Hazleton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 570-459-2901 Email: HemonCCTrials@geisinger.edu
Lewisburg
Geisinger Medical Oncology-Lewisburg
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 570-374-8555 Email: HemonCCTrials@geisinger.edu
Lewistown
Lewistown Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 717-242-7703 Email: HemonCCTrials@geisinger.edu
Philadelphia
Thomas Jefferson University Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 215-955-6084
Pottsville
Geisinger Cancer Services-Pottsville
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-275-6401 Email: HemonCCTrials@geisinger.edu
Scranton
Community Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 570-703-4768 Email: HemonCCTrials@geisinger.edu
Selinsgrove
Geisinger Medical Oncology-Selinsgrove
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 570-374-8555 Email: HemonCCTrials@geisinger.edu
State College
Geisinger Medical Group
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 570-271-5251 Email: HemonCCTrials@geisinger.edu
Wilkes-Barre
Geisinger Wyoming Valley / Henry Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 570-271-5251 Email: HemonCCTrials@geisinger.edu

South Carolina

Charleston
Medical University of South Carolina
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 843-792-9321 Email: hcc-clinical-trials@musc.edu
Easley
Greenville Health System Cancer Institute-Easley
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-241-6251 Email: kwilliams8@ghs.org
Greenville
Greenville Health System Cancer Institute-Butternut
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-241-6251 Email: kwilliams8@ghs.org
Greenville Health System Cancer Institute-Eastside
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-241-6251 Email: kwilliams8@ghs.org
Greenville Health System Cancer Institute-Faris
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-241-6251 Email: kwilliams8@ghs.org
Greenville Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-241-6251 Email: kwilliams8@ghs.org
Saint Francis Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-603-6213 Email: meissa_beckman@bshsi.org
Saint Francis Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-603-6213 Email: meissa_beckman@bshsi.org
Greer
Greenville Health System Cancer Institute-Greer
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-241-6251 Email: kwilliams8@ghs.org
Seneca
Greenville Health System Cancer Institute-Seneca
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-241-6251 Email: kwilliams8@ghs.org
Spartanburg
Greenville Health System Cancer Institute-Spartanburg
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 864-241-6251 Email: kwilliams8@ghs.org

South Dakota

Sioux Falls
Sanford Cancer Center Oncology Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 605-312-3320
Sanford USD Medical Center - Sioux Falls
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 605-312-3320 Email: OncologyClinicalTrialsSF@SanfordHealth.org

Tennessee

Chattanooga
Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Hixson
Pulmonary Medicine Center of Chattanooga-Hixson
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Ooltewah
Memorial GYN Plus
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org

Texas

Bryan
Saint Joseph Regional Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org

Washington

Aberdeen
Providence Regional Cancer System-Aberdeen
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-412-8958 Email: deidre.dillon@providence.org
Anacortes
Cancer Care Center at Island Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-299-1336 Email: eoates@islandhospital.org
Bellevue
Swedish Cancer Institute-Eastside Oncology Hematology
Status: Temporarily closed to accrual
Contact: Site Public Contact Email: CancerResearch@swedish.org
Bellingham
PeaceHealth Saint Joseph Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-715-4133 Email: mjohnson9@peacehealth.org
Bremerton
Harrison HealthPartners Hematology and Oncology-Bremerton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Harrison Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Burien
Highline Medical Center-Main Campus
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Centralia
Providence Regional Cancer System-Centralia
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-412-8958 Email: deidre.dillon@providence.org
Edmonds
Swedish Medical Center-Edmonds
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 206-215-3086 Email: PCRC-NCORP@Swedish.org
Enumclaw
Saint Elizabeth Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Everett
Providence Regional Cancer Partnership
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 425-261-3529 Email: marilyn.birchman@providence.org
Federal Way
Saint Francis Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Issaquah
Swedish Cancer Institute-Issaquah
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 206-215-3086 Email: PCRC-NCORP@Swedish.org
Kennewick
Kadlec Clinic Hematology and Oncology
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 509-783-4637 Email: research@kadlecmed.org
Lacey
Providence Regional Cancer System-Lacey
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-412-8958 Email: deidre.dillon@providence.org
Lakewood
Saint Clare Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Longview
PeaceHealth Saint John Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-514-2016 Email: kmakin-bond@peacehealth.org
Poulsbo
Harrison HealthPartners Hematology and Oncology-Poulsbo
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Seattle
Kaiser Permanente Washington
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 206-215-3086 Email: PCRC-NCORP@Swedish.org
Minor and James Medical PLLC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 206-386-9501
Pacific Gynecology Specialists
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 206-215-3086 Email: PCRC-NCORP@Swedish.org
Swedish Medical Center-Ballard Campus
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 206-215-3086 Email: PCRC-NCORP@Swedish.org
Swedish Medical Center-Cherry Hill
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 206-215-3086 Email: PCRC-NCORP@Swedish.org
Swedish Medical Center-First Hill
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 206-215-3086 Email: PCRC-NCORP@Swedish.org
Sedro-Woolley
PeaceHealth United General Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-788-8240
Shelton
Providence Regional Cancer System-Shelton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-412-8958 Email: deidre.dillon@providence.org
Spokane
Evergreen Hematology and Oncology PS
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 509-464-2873
Rockwood Cancer Treatment Center-DHEC-Downtown
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 509-724-4454 Email: apope@rockwoodclinic.com
Rockwood North Cancer Treatment Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 509-724-4454 Email: apope@rockwoodclinic.com
Spokane Valley
Rockwood Clinic Cancer Treatment Center-Valley
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 509-724-4454 Email: apope@rockwoodclinic.com
Tacoma
Franciscan Research Center-Northwest Medical Plaza
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Northwest Medical Specialties PLLC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 308-398-6518 Email: clinicaltrials@sfmc-gi.org
Vancouver
PeaceHealth Southwest Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-514-3940 Email: kmakin-bond@peacehealth.org
Walla Walla
Providence Saint Mary Regional Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 509-897-5993 Email: Cheryl.Dodd@providence.org
Yakima
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 509-574-3535 Email: Memorial-ClinicalTrials@yvmh.org
Yelm
Providence Regional Cancer System-Yelm
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 360-412-8958 Email: deidre.dillon@providence.org

West Virginia

Huntington
Edwards Comprehensive Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 304-399-6617

Wisconsin

Ashland
Ashland Memorial Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Duluth Clinic Ashland
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 218-786-3308 Email: CancerTrials@EssentiaHealth.org
Burlington
Aurora Cancer Care-Southern Lakes VLCC
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Eau Claire
Marshfield Clinic Cancer Center at Sacred Heart
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-782-8581 Email: oncology.clinical.trials@marshfieldresearch.org
Fond Du Lac
Aurora Health Center-Fond du Lac
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Germantown
Aurora Health Care Germantown Health Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Grafton
Aurora Cancer Care-Grafton
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Green Bay
Aurora BayCare Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Kenosha
Aurora Cancer Care-Kenosha South
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Marinette
Aurora Bay Area Medical Group-Marinette
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Marshfield
Marshfield Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-782-8581 Email: oncology.clinical.trials@marshfieldresearch.org
Milwaukee
Aurora Cancer Care-Milwaukee
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Aurora Saint Luke's Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 773-702-9171 Email: protocols@AllianceNCTN.org
Aurora Sinai Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Froedtert and the Medical College of Wisconsin
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-805-4380
Minocqua
Marshfield Clinic-Minocqua Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-782-8581 Email: oncology.clinical.trials@marshfieldresearch.org
New Richmond
Cancer Center of Western Wisconsin
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 952-993-1517 Email: mmcorc@healthpartners.com
Oshkosh
Vince Lombardi Cancer Clinic - Oshkosh
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Racine
Aurora Cancer Care-Racine
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Rice Lake
Lakeview Medical Center-Marshfield Clinic
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-782-8581 Email: oncology.clinical.trials@marshfieldresearch.org
Marshfield Clinic-Rice Lake Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-782-8581 Email: oncology.clinical.trials@marshfieldresearch.org
Sheboygan
Vince Lombardi Cancer Clinic-Sheboygan
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Stevens Point
Ascension Saint Michael's Hospital
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 888-823-5923 Email: ctsucontact@westat.com
Marshfield Clinic Stevens Point Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-782-8581 Email: oncology.clinical.trials@marshfieldresearch.org
Summit
Aurora Medical Center in Summit
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Two Rivers
Vince Lombardi Cancer Clinic-Two Rivers
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Wausau
Marshfield Clinic-Wausau Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-782-8581 Email: oncology.clinical.trials@marshfieldresearch.org
Wauwatosa
Aurora Cancer Care-Milwaukee West
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
West Allis
Aurora West Allis Medical Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 414-302-2304 Email: ncorp@aurora.org
Weston
Marshfield Clinic - Weston Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-782-8581 Email: oncology.clinical.trials@marshfieldresearch.org
Wisconsin Rapids
Marshfield Clinic - Wisconsin Rapids Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-782-8581 Email: oncology.clinical.trials@marshfieldresearch.org

Wyoming

Cheyenne
Cheyenne Regional Medical Center-West
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 303-777-2663 Email: ccrp@co-cancerresearch.org
Cody
Billings Clinic-Cody
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 800-996-2663 Email: research@billingsclinic.org
Sheridan
Welch Cancer Center
Status: Temporarily closed to accrual
Contact: Site Public Contact
Phone: 406-969-6060 Email: mccinfo@mtcancer.org

Trial Objectives and Outline

PRIMARY OBJECTIVES:

I. To evaluate the confirmed response rate of single agent nivolumab and dual agent nivolumab plus ipilimumab in patients with locally advanced/unresectable or metastatic soft tissue sarcoma.

SECONDARY OBJECTIVES:

I. To evaluate adverse event rates (National Cancer Institute [NCI] Common Terminology Criteria for Adverse Events [CTCAE] version [v]4.0) within each treatment arm.

II. To evaluate duration of response, clinical benefit rate, time to progression, progression-free survival, and overall survival within each treatment arm.

TERTIARY OBJECTIVES:

I. To potentially detect an early signal of confirmed response rate within a histologically defined patient cohort.

II. To assess the potential association between programmed cell death 1 ligand 1 (PD-L1) expression (by immunohistochemistry [IHC]) and clinical outcome, within each treatment.

III. To evaluate associations between selected biomarker measured in serial peripheral blood and with clinical efficacy, within each treatment.

IV. To evaluate the association between selected biomarker measured in tumor tissue with clinical efficacy, within each treatment.

V. To evaluate the association between baseline tumor mutational burden and neoantigen production with clinical efficacy within each treatment.

VI. To evaluate secondary endpoints within patients crossing over to dual agent nivolumab plus ipilimumab after experiencing progressive disease while receiving single agent nivolumab.

VII. To evaluate correlative science objectives endpoints within patients crossing over to dual agent nivolumab plus ipilimumab after experiencing progressive disease while receiving single agent nivolumab.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients receive nivolumab intravenously (IV) over 30 minutes once every 2 weeks. Courses repeat every 42 days for up to 108 weeks in the absence of disease progression or unacceptable toxicity. Patients who progress after 10 weeks on single agent nivolumab may elect to cross over to Arm II.

ARM II: Patients receive nivolumab IV over 30 minutes and ipilimumab IV over 90 minutes once every 3 weeks for 12 weeks. Patients then receive nivolumab IV over 30 minutes every 2 weeks. Courses repeat every 42 days for up to 108 weeks in the absence of disease progression or unacceptable toxicity. Patients who progress by imaging during the first 12 weeks of therapy may continue treatment, at the discretion of the patient and treating investigator.

After completion of study treatment, patients are followed up at 4 weeks and then every 6 months for 3 years.

Trial Phase & Type

Trial Phase

Phase II

Trial Type

Treatment

Lead Organization

Lead Organization
Alliance for Clinical Trials in Oncology

Principal Investigator
Sandra Pierina D'Angelo

Trial IDs

Primary ID A091401
Secondary IDs NCI-2015-00260
Clinicaltrials.gov ID NCT02500797