Testosterone in Treating Postmenopausal Patients with Arthralgia Caused by Adjuvant Aromatase Inhibitor Treatment

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Basic Trial Information

PhaseTypeStatusAgeTrial IDs
Phase IIIBiomarker/Laboratory analysis, Supportive care, TreatmentActive18 and overA221102
NCI-2012-00719, CDR0000730083, CALGB-A221102, NCCTG-N10C7, NCT01573442

Trial Description

Summary

This randomized phase III trial studies testosterone to see how well it works compared to placebo in treating postmenopausal patients with arthralgia (joint pain) caused by anastrozole or letrozole. Testosterone may help relieve moderate or severe arthralgia associated with the use of aromatase inhibitors, such as anastrozole or letrozole.

Further Study Information

PRIMARY OBJECTIVES

I. To determine whether testosterone will reduce aromatase inhibitor (AI)-induced arthralgia and associated joint symptoms.

SECONDARY OBJECTIVES:

I. To explore whether testosterone will have an acceptable safety and tolerability profile, with particular reference to androgenic adverse events including acne, hirsutism, and alopecia.

TERTIARY OBJECTIVES:

I. To explore whether testosterone will reduce AI-induced arthralgias and associated joint symptoms and their interference with activity.

II. To explore whether testosterone will reduce the incidence of hot flashes.

III. To explore whether testosterone will modify libido or change quality of life.

IV. To explore whether identified single nucleotide polymorphisms (SNPs), that were associated with more AI-associated arthralgias in a previous prospective trial, are more commonly seen in the patients entered into the present clinical trial, than are observed in the normal population.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

Arm I: Patients receive testosterone transdermally on day 1 and then at 3 months.

Arm II: Patients receive placebo transdermally on day 1 and then at 3 months.

After completion of study treatment, patients are followed up for 6 months.

Eligibility Criteria

Inclusion Criteria:

Receiving anastrozole (1 mg) or letrozole (2.5 mg) orally once a day, for >= 21 days prior to registration and plan to continue throughout the duration of study

Body Mass Index (BMI) between 18 and 35 kg/m^2

Women who have undergone a total mastectomy or breast-conserving surgery for primary breast cancer +/- chemotherapy, +/- radiotherapy

Must have BOTH estrogen receptor (ER) and progesterone receptor (PR)-positive tumors and BOTH must be >= 26% positive; alternatively, if ER and PR are determined by Allred score, the score needs to be 5 or higher

Women who are postmenopausal by surgery, radiotherapy, or presence of natural amenorrhea >= 12 months

>= 5/10 arthralgia (in hands, wrist, knees, or hips) while being treated with anastrozole or letrozole which is felt by the patient to be caused by their aromatase inhibitor, as measured by verbally addressing the following question: please rate your pain by picking a number, from 0 to 10 (0 being none and 10 being as bad as you can imagine) that best describes your pain from your aromatase inhibitor breast cancer medication on AVERAGE, over the past week

Note: Patients may, or may not, be taking non-opioid analgesics

Ability to complete questionnaire(s) by themselves or with assistance

Eastern Cooperative Oncology Group (ECOG) performance status (PS) 0, 1, or 2

Willing to provide informed written consent

Willing to return to an Alliance enrolling institution for follow-up

Willing to provide blood samples for correlative research purposes

Laboratory values obtained =< 365* days prior to registration:

Note: Without medical situations that should change these parameters since they were done

Creatinine =< 1.5 x upper limit of normal (ULN)

Hemoglobin > 11 g/dL

White blood cell (WBC) > 3.0

Platelet count > 100,000

Serum glutamic oxaloacetic transaminase (SGOT) (aspartate aminotransferase [AST]) =< 1.5 x ULN

Exclusion Criteria:

Presence of residual or recurrent cancer (locally or metastatic)

Diabetes mellitus or glucose intolerance, defined as a fasting glucose > 125 mg/dL

History of coronary artery disease (angina or myocardial infarction)

Patients on hormone-replacement therapy (HRT) =< 4 weeks prior to registration; this includes the use of vaginal estrogen therapy

Known hypersensitivity to any component of testosterone

Prolonged systemic corticosteroid treatment, except for topical applications (e.g., for rash), inhaled sprays (e.g., for obstructive airway diseases), eye drops, or local insertion (e.g., intra-articular)

Note: Short duration (< 2 weeks) of systemic corticosteroids is allowed (e.g., for chronic obstructive pulmonary disease), but not within 30 days prior to registration

Receiving any other investigational agent

History of a deep venous thrombosis or a thromboembolism

Concurrent use of the aromatase inhibitor exemestane

Concurrent radiation therapy or chemotherapy

Current or planned use of cyclosporine, anticoagulants, oxyphenbutazone, insulin, oral or injectable vitamin D doses over 4,000 IU/day, or tamoxifen

Trial Contact Information

Trial Lead Organizations / Sponsors / Collaborators

Alliance for Clinical Trials in Oncology

  • National Cancer Institute
Charles Lawrence Loprinzi, Principal Investigator

Trial Sites

U.S.A.

Alaska
Anchorage

Alaska Breast Care and Surgery LLC

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Alaska Oncology and Hematology LLC

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Alaska Women's Cancer Care

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Anchorage Associates in Radiation Medicine

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Anchorage Oncology Centre

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Anchorage Radiation Therapy Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Katmai Oncology Group

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Providence Alaska Medical Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Arkansas
Hot Springs

Mercy Cancer Center-Hot Springs

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

California
Auburn

Sutter Auburn Faith Hospital

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Sutter Cancer Centers Radiation Oncology Services-Auburn

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Berkeley

Alta Bates Summit Medical Center-Herrick Campus

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Burbank

Providence Saint Joseph Medical Center/Disney Family Cancer Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Burlingame

Mills - Peninsula Hospitals

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Cameron Park

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Castro Valley

Eden Hospital Medical Center

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Davis

Sutter Davis Hospital

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Dublin

Epic Care-Dublin

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Emeryville

Bay Area Breast Surgeons Inc

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Epic Care Partners in Cancer Care

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Los Angeles

Cedars-Sinai Medical Center

Armando Elario Giuliano
Ph: 310-423-8965

Armando Elario Giuliano
Principal Investigator

Martinez

Contra Costa Regional Medical Center

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Modesto

Memorial Medical Center

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Mountain View

Palo Alto Medical Foundation-Camino Division

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Palo Alto Medical Foundation-Gynecologic Oncology

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Novato

Sutter Cancer Research Consortium

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Oakland

Alta Bates Summit Medical Center - Summit Campus

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Bay Area Tumor Institute

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Palo Alto

Palo Alto Medical Foundation Health Care

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Roseville

Sutter Cancer Centers Radiation Oncology Services-Roseville

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Sutter Roseville Medical Center

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Sacramento

Sutter General Hospital

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

San Francisco

California Pacific Medical Center-Pacific Campus

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Santa Cruz

Palo Alto Medical Foundation-Santa Cruz

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Santa Rosa

Sutter Pacific Medical Foundation

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Sunnyvale

Palo Alto Medical Foundation-Sunnyvale

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Vacaville

Sutter Cancer Centers Radiation Oncology Services-Vacaville

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Vallejo

Sutter Solano Medical Center/Cancer Center

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Colorado
Colorado Springs

Penrose-Saint Francis Healthcare

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Denver

Porter Adventist Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Durango

Mercy Medical Center

Mehmet Sitki Copur
Ph: 303-777-2663
Email: kgeisen@co-cancerresearch.org

Mehmet Sitki Copur
Principal Investigator

Southwest Oncology PC

Keren Sturtz
Ph: 303-777-2663
Email: kgeisen@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Lakewood

Saint Anthony Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Littleton

Littleton Adventist Hospital

Keren Sturtz
Ph: 303-777-2663
Email: kgeisen@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Longmont

Longmont United Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Parker

Parker Adventist Hospital

Keren Sturtz
Ph: 303-777-2663
Email: kgeisen@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Pueblo

Saint Mary Corwin Medical Center

Keren Sturtz
Ph: 303-777-2663
Email: kgeisen@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Delaware
Lewes

Beebe Medical Center

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Newark

Christiana Care Health System-Christiana Hospital

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Delaware Clinical and Laboratory Physicians PA

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Helen F Graham Cancer Center

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Medical Oncology Hematology Consultants PA

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Regional Hematology and Oncology PA

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Rehoboth Beach

Beebe Health Campus

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Seaford

Nanticoke Memorial Hospital

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Wilmington

Christiana Care Health System-Wilmington Hospital

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Florida
Lakeland

Lakeland Regional Cancer Center

Madhavi L. Venigalla
Ph: 863-904-1900

Madhavi L. Venigalla
Principal Investigator

Georgia
Athens

University Cancer and Blood Center LLC

Sharad Anant Ghamande
Ph: 706-721-1663
Email: cancer@augusta.edu

Sharad Anant Ghamande
Principal Investigator

Atlanta

Northside Hospital

Colleen S. Austin
Email: ClinicalTrials@northside.com

Colleen S. Austin
Principal Investigator

Augusta

Augusta University Medical Center

Sharad Anant Ghamande
Ph: 706-721-1663
Email: cancer@augusta.edu

Sharad Anant Ghamande
Principal Investigator

Columbus

John B Amos Cancer Center

Andrew W. Pippas
Ph: 706-660-6404

Andrew W. Pippas
Principal Investigator

Decatur

Dekalb Medical Center

Sharad Anant Ghamande
Ph: 706-721-1663
Email: cancer@augusta.edu

Sharad Anant Ghamande
Principal Investigator

Macon

Medical Center of Central Georgia

Frederick M. Schnell
Ph: 478-633-1226

Frederick M. Schnell
Principal Investigator

Savannah

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Howard A. Zaren
Ph: 800-622-6877

Howard A. Zaren
Principal Investigator

Idaho
Boise

Saint Luke's Mountain States Tumor Institute

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Coeur D'Alene

Kootenai Medical Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Fruitland

Saint Luke's Mountain States Tumor Institute - Fruitland

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Meridian

Saint Luke's Mountain States Tumor Institute - Meridian

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Nampa

Saint Luke's Mountain States Tumor Institute - Nampa

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Post Falls

Kootenai Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Sandpoint

Kootenai Cancer

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Twin Falls

Saint Luke's Mountain States Tumor Institute-Twin Falls

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Illinois
Aurora

Rush - Copley Medical Center

Kendrith M. Rowland
Ph: 800-446-5532

Kendrith M. Rowland
Principal Investigator

Bloomington

Illinois CancerCare-Bloomington

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Saint Joseph Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Canton

Illinois CancerCare-Canton

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Carbondale

Memorial Hospital of Carbondale

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Carthage

Illinois CancerCare-Carthage

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Centralia

Centralia Oncology Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Chicago

Weiss Memorial Hospital

Stuart A. Krauss
Ph: 773-564-5044

Stuart A. Krauss
Principal Investigator

Danville

Carle on Vermilion

Kendrith M. Rowland
Ph: 800-446-5532

Kendrith M. Rowland
Principal Investigator

Decatur

Cancer Care Center of Decatur

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Decatur Memorial Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Effingham

Carle Physician Group-Effingham

Kendrith M. Rowland
Ph: 800-446-5532

Kendrith M. Rowland
Principal Investigator

Crossroads Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Eureka

Illinois CancerCare-Eureka

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Galesburg

Illinois CancerCare-Galesburg

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Western Illinois Cancer Treatment Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Geneva

Northwestern Medicine Cancer Center Delnor

John D. Ayers
Ph: 630-315-1918
Email: Claudine.Gamster@CadenceHealth.org

John D. Ayers
Principal Investigator

Harvey

Ingalls Memorial Hospital

Mark Farrell Kozloff
Ph: 708-915-4673
Email: clinicaltrials@ingalls.org

Mark Farrell Kozloff
Principal Investigator

Kewanee

Illinois CancerCare-Kewanee Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Macomb

Illinois CancerCare-Macomb

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Mattoon

Carle Physician Group-Mattoon/Charleston

Kendrith M. Rowland
Ph: 800-446-5532

Kendrith M. Rowland
Principal Investigator

Moline

Garneau, Stewart C MD (UIA Investigator)

David Martens Spector
Ph: 309-779-4200

David Martens Spector
Principal Investigator

Spector, David MD (UIA Investigator)

David Martens Spector
Ph: 309-779-4200

David Martens Spector
Principal Investigator

Trinity Medical Center

David Martens Spector
Ph: 309-779-4200

David Martens Spector
Principal Investigator

Mount Vernon

Good Samaritan Regional Health Center

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Ottawa

Illinois CancerCare-Ottawa Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Pekin

Illinois CancerCare-Pekin

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Peoria

Illinois CancerCare-Peoria

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Methodist Medical Center of Illinois

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Radiation Oncology at Peoria Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Peru

Illinois CancerCare-Peru

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Valley Radiation Oncology

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Princeton

Illinois CancerCare-Princeton

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

River Forest

West Suburban Medical Center

Isoken Koko
Ph: 708-488-0882

Isoken Koko
Principal Investigator

Springfield

Central Illinois Hematology Oncology Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Memorial Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Southern Illinois University School of Medicine

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Springfield Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Swansea

Cancer Care Specialists of Illinois-Swansea

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Urbana

Carle Cancer Center

Kendrith M. Rowland
Ph: 800-446-5532

Kendrith M. Rowland
Principal Investigator

The Carle Foundation Hospital

Kendrith M. Rowland
Ph: 800-446-5532

Kendrith M. Rowland
Principal Investigator

Warrenville

Northwestern Medicine Cancer Center Warrenville

John D. Ayers
Ph: 630-315-1918
Email: Claudine.Gamster@CadenceHealth.org

John D. Ayers
Principal Investigator

Yorkville

Rush-Copley Healthcare Center

Kendrith M. Rowland
Ph: 800-446-5532

Kendrith M. Rowland
Principal Investigator

Indiana
Mishawaka

Memorial Regional Cancer Center Day Road

Thomas Joseph Reid
Ph: 800-284-7370

Thomas Joseph Reid
Principal Investigator

Richmond

Reid Health

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

South Bend

Memorial Hospital of South Bend

Thomas Joseph Reid
Ph: 800-284-7370

Thomas Joseph Reid
Principal Investigator

Iowa
Bettendorf

Constantinou, Costas L MD (UIA Investigator)

David Martens Spector
Ph: 309-779-4200

David Martens Spector
Principal Investigator

Cedar Rapids

Mercy Hospital

Deborah Weil Wilbur
Ph: 515-241-3305

Deborah Weil Wilbur
Principal Investigator

Oncology Associates at Mercy Medical Center

Deborah Weil Wilbur
Ph: 515-241-3305

Deborah Weil Wilbur
Principal Investigator

Clive

Medical Oncology and Hematology Associates-West Des Moines

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Mercy Cancer Center-West Lakes

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Council Bluffs

Alegent Health Mercy Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Creston

Greater Regional Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Des Moines

Medical Oncology and Hematology Associates-Laurel

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Mercy Medical Center - Des Moines

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

West Des Moines

Mercy Medical Center-West Lakes

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Kansas
Chanute

Cancer Center of Kansas - Chanute

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Dodge City

Cancer Center of Kansas - Dodge City

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

El Dorado

Cancer Center of Kansas - El Dorado

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Fort Scott

Cancer Center of Kansas - Fort Scott

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Independence

Cancer Center of Kansas-Independence

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Kingman

Cancer Center of Kansas-Kingman

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Lawrence

Lawrence Memorial Hospital

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Liberal

Cancer Center of Kansas-Liberal

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Newton

Cancer Center of Kansas - Newton

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Parsons

Cancer Center of Kansas - Parsons

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Pratt

Cancer Center of Kansas - Pratt

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Salina

Cancer Center of Kansas - Salina

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Wellington

Cancer Center of Kansas - Wellington

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Wichita

Associates In Womens Health

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Cancer Center of Kansas - Wichita

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Cancer Center of Kansas-Wichita Medical Arts Tower

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Via Christi Regional Medical Center

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Wichita NCI Community Oncology Research Program

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Winfield

Cancer Center of Kansas - Winfield

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Kentucky
Bardstown

Flaget Memorial Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Corbin

Commonwealth Cancer Center-Corbin

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Edgewood

Saint Elizabeth Medical Center South

Joseph Michael Guenther
Ph: 859-301-5473
Email: darla.hehman@stelizabeth.com

Joseph Michael Guenther
Principal Investigator

Fort Thomas

Saint Elizabeth Fort Thomas

Joseph Michael Guenther
Ph: 859-301-5473
Email: darla.hehman@stelizabeth.com

Joseph Michael Guenther
Principal Investigator

Lexington

Saint Joseph Hospital East

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Saint Joseph Radiation Oncology Resource Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Louisville

Jewish Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Jewish Hospital Medical Center Northeast

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Saints Mary and Elizabeth Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Shepherdsville

Jewish Hospital Medical Center South

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Maryland
Rockville

Unspecified Site

Charles Lawrence Loprinzi
Ph: 507-284-4849
Email: loprinzi@mayo.edu

Charles Lawrence Loprinzi
Principal Investigator

Minnesota
Bemidji

Sanford Clinic North-Bemidgi

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Mankato

Mayo Clinic Health Systems-Mankato

Mohmmad Junaid Ranginwala
Ph: 855-776-0015

Mohmmad Junaid Ranginwala
Principal Investigator

Rochester

Mayo Clinic

Charles Lawrence Loprinzi
Ph: 507-538-7623

Charles Lawrence Loprinzi
Principal Investigator

Missouri
Ballwin

Saint Louis Cancer and Breast Institute-Ballwin

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Bolivar

Central Care Cancer Center-Carrie J Babb Cancer Center

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Bonne Terre

Parkland Health Center-Bonne Terre

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Cape Girardeau

Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Southeast Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Jefferson City

Capital Region Medical Center-Goldschmidt Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Joplin

Freeman Health System

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Mercy Hospital-Joplin

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Rolla

Phelps County Regional Medical Center

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Saint John's Clinic-Rolla-Cancer and Hematology

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Saint Louis

Mercy Hospital Saint Louis

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Missouri Baptist Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Saint Louis Cancer and Breast Institute-South City

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Washington University School of Medicine

Rebecca L. Aft
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Rebecca L. Aft
Principal Investigator

Sainte Genevieve

Sainte Genevieve County Memorial Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Springfield

CoxHealth South Hospital

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Mercy Hospital Springfield

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Sullivan

Missouri Baptist Sullivan Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Sunset Hills

Missouri Baptist Outpatient Center-Sunset Hills

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Washington

Mercy Hospital Washington

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Montana
Anaconda

Community Hospital of Anaconda

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Billings

Billings Clinic Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Montana Cancer Consortium NCORP

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Saint Vincent Healthcare

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Bozeman

Bozeman Deaconess Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Great Falls

Benefis Healthcare- Sletten Cancer Institute

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Great Falls Clinic

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Helena

Saint Peter's Community Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Kalispell

Kalispell Regional Medical Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Missoula

Community Medical Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Nebraska
Grand Island

CHI Health Saint Francis

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Kearney

CHI Health Good Samaritan

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Heartland Hematology and Oncology

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Lincoln

Saint Elizabeth Regional Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Omaha

Alegent Health Bergan Mercy Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Alegent Health Immanuel Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Alegent Health Lakeside Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Creighton University Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Hemotology and Oncology Consultants PC

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Nebraska Methodist Hospital

Kirsten M. Hotton Leu
Ph: 402-393-3110

Kirsten M. Hotton Leu
Principal Investigator

University of Nebraska Medical Center

Elizabeth C. Reed
Ph: 402-559-6941
Email: unmcrsa@unmc.edu

Elizabeth C. Reed
Principal Investigator

Papillion

Midlands Community Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Nevada
Henderson

21st Century Oncology - Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer and Blood Specialists-Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada - Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada-Southeast Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Las Vegas Cancer Center-Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Las Vegas

21st Century Oncology

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

21st Century Oncology - Fort Apache

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

21st Century Oncology - Vegas Tenaya

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer and Blood Specialists-Fort Apache

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer and Blood Specialists-Shadow

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer and Blood Specialists-Tenaya

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer Therapy and Integrative Medicine

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada - Central Valley

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada - Northwest

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada-Summerlin

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-San Martin

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Las Vegas Cancer Center-Medical Center

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Nevada Cancer Research Foundation CCOP

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Radiation Oncology Centers of Nevada Central

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Radiation Oncology Centers of Nevada Southeast

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

University Medical Center of Southern Nevada

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

New Jersey
Vineland

Inspira Medical Center Vineland

Kush Sachdeva
Ph: 856-641-7933

Kush Sachdeva
Principal Investigator

Woodbury

Inspira Medical Center Woodbury

Carl J. Minniti
Ph: 856-641-7933

Carl J. Minniti
Principal Investigator

North Carolina
Belmont

Gaston Hematology and Oncology Associates-Belmont

William J. Charles
Ph: 704-865-5210

William J. Charles
Principal Investigator

Charlotte

Carolina Surgical Clinic of Charlotte PA

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Novant Health Presbyterian Medical Center

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Oncology Specialists of Charlotte

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Southern Oncology Specialists-Charlotte

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Clinton

Southeastern Medical Oncology Center-Clinton

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Gastonia

CaroMont Regional Medical Center

William J. Charles
Ph: 704-865-5210

William J. Charles
Principal Investigator

Gaston Hematology and Oncology Associates

William J. Charles
Ph: 704-865-5210

William J. Charles
Principal Investigator

Goldsboro

Southeastern Medical Oncology Center-Goldsboro

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Wayne Memorial Hospital

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Huntersville

Lake Norman Hematology Oncology Specialists-Huntersville

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Southern Oncology Specialists-Huntersville

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Jacksonville

Southeastern Medical Oncology Center-Jacksonville

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Kinston

Kinston Medical Specialists PA

Peter Robins Watson
Ph: 252-559-2200

Peter Robins Watson
Principal Investigator

Matthews

Matthews Radiation Oncology Center

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Novant Health Cancer Specialists-Matthews

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Mooresville

Lake Norman Hematology Oncology Specialists-Mooresville

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Wilson

Southeastern Medical Oncology Center-Wilson

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

North Dakota
Bismarck

Sanford Bismarck Medical Center

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Fargo

Roger Maris Cancer Center

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Sanford Clinic North-Fargo

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Sanford Medical Center-Fargo

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Ohio
Akron

Akron General Medical Center

Esther Hoogland Rehmus
Ph: 330-344-6348

Esther Hoogland Rehmus
Principal Investigator

Centerville

Dayton Physicians LLC-Miami Valley South

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Miami Valley Hospital South

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Cincinnati

Bethesda North Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Good Samaritan Hospital - Cincinnati

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Oncology Hematology Care Inc-Kenwood

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

TriHealth Cancer Institute-Anderson

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

TriHealth Cancer Institute-Westside

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Dayton

Dayton Physicians LLC-Samaritan North

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Good Samaritan Hospital - Dayton

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Miami Valley Hospital

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Samaritan North Health Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Findlay

Armes Family Cancer Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Blanchard Valley Hospital

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Orion Cancer Care

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Franklin

Atrium Medical Center-Middletown Regional Hospital

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Dayton Physicians LLC-Atrium

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Greenville

Dayton Physicians LLC-Wayne

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Wayne Hospital

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Kettering

Greater Dayton Cancer Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Kettering Medical Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Middletown

Dayton Physicians LLC-Signal Point

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Sidney

Dayton Physicians LLC-Wilson

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Springfield

Springfield Regional Cancer Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Springfield Regional Medical Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Troy

Dayton Physicians LLC-Upper Valley

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Upper Valley Medical Center

Howard M. Gross
Ph: 937-775-1350
Email: som_dcop@wright.edu

Howard M. Gross
Principal Investigator

Wright-Patterson Afb

Wright-Patterson Medical Center

Susannah Catherine Cooper
Ph: 937-775-1350
Email: som_dcop@wright.edu

Susannah Catherine Cooper
Principal Investigator

Oregon
Bend

Saint Charles Medical Center-Bend

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Clackamas

Clackamas Radiation Oncology Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Providence Oncology and Hematology Care Southeast

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Coos Bay

Bay Area Hospital

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Newberg

Providence Newberg Medical Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Oregon City

Providence Willamette Falls Medical Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Portland

Providence Portland Medical Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Providence Saint Vincent Medical Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Puerto Rico
San Juan

San Juan City Hospital

Luis Baez-Diaz
Ph: 787-767-3733
Email: baez.luis@sanjuanccop.org

Luis Baez-Diaz
Principal Investigator

South Carolina
Charleston

Bon Secours Saint Francis Hospital

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Charleston Hematology Oncology Associates PA-St. Francis

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Charleston Hematology Oncology Associates-Roper

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Lowcountry Hematology Oncology PA-North Charleston

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Roper Hospital

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Easley

Greenville Health System Cancer Institute-Easley

Jeffrey Kent Giguere
Ph: 864-241-6251

Jeffrey Kent Giguere
Principal Investigator

Greenville

Greenville Health System Cancer Institute-Butternut

Jeffrey Kent Giguere
Ph: 864-241-6251

Jeffrey Kent Giguere
Principal Investigator

Greenville Health System Cancer Institute-Eastside

Jeffrey Kent Giguere
Ph: 864-241-6251

Jeffrey Kent Giguere
Principal Investigator

Greenville Health System Cancer Institute-Faris

Jeffrey Kent Giguere
Ph: 864-241-6251

Jeffrey Kent Giguere
Principal Investigator

Greenville Memorial Hospital

Jeffrey Kent Giguere
Ph: 864-241-6251

Jeffrey Kent Giguere
Principal Investigator

Greer

Greenville Health System Cancer Institute-Greer

Jeffrey Kent Giguere
Ph: 864-241-6251

Jeffrey Kent Giguere
Principal Investigator

Mount Pleasant

Lowcountry Hematology Oncology PA-Mount Pleasant

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Seneca

Greenville Health System Cancer Institute-Seneca

Jeffrey Kent Giguere
Ph: 864-241-6251

Jeffrey Kent Giguere
Principal Investigator

Spartanburg

Greenville Health System Cancer Institute-Spartanburg

Jeffrey Kent Giguere
Ph: 864-241-6251

Jeffrey Kent Giguere
Principal Investigator

South Dakota
Sioux Falls

Sanford Cancer Center-Oncology Clinic

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Sanford USD Medical Center - Sioux Falls

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Tennessee
Chattanooga

Memorial Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Hixson

Pulmonary Medicine Center of Chattanooga-Hixson

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Ooltewah

Memorial GYN Plus

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Utah
Salt Lake City

Huntsman Cancer Institute/University of Utah

Anna C. Beck
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

Anna C. Beck
Principal Investigator

South Jordan

South Jordan Health Center

Anna C. Beck
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

Anna C. Beck
Principal Investigator

Virginia
Fairfax

IMG Hematology Oncology 8501

Mary Judith Wilkinson
Ph: 703-720-5210
Email: Stephanie.VanBebber@inova.org

Mary Judith Wilkinson
Principal Investigator

Inova Fair Oaks Hospital

Mary Judith Wilkinson
Ph: 703-720-5210
Email: Stephanie.VanBebber@inova.org

Mary Judith Wilkinson
Principal Investigator

Martinsville

Memorial Hospital Of Martinsville

Sreedhar Katragadda
Ph: 276-666-7827

Sreedhar Katragadda
Principal Investigator

Washington
Aberdeen

Providence Regional Cancer System-Aberdeen

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Anacortes

Cancer Care Center at Island Hospital

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Bellingham

PeaceHealth Saint Joseph Medical Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Bremerton

Harrison HealthPartners Hematology and Oncology-Bremerton

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Harrison Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Burien

Highline Medical Center-Main Campus

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Centralia

Providence Regional Cancer System-Centralia

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Edmonds

Swedish Medical Center-Edmonds

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Enumclaw

Saint Elizabeth Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Everett

Providence Regional Cancer Partnership

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Federal Way

Saint Francis Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Issaquah

Swedish Cancer Institute-Issaquah

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Lacey

Providence Regional Cancer System-Lacey

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Lakewood

Saint Clare Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Longview

PeaceHealth Saint John Medical Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Poulsbo

Harrison HealthPartners Hematology and Oncology-Poulsbo

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Seattle

Group Health Cooperative-Seattle

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Pacific Gynecology Specialists

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Swedish Medical Center-Ballard Campus

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Swedish Medical Center-First Hill

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Shelton

Providence Regional Cancer System-Shelton

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Spokane

Rockwood Cancer Treatment Center-DHEC-Downtown

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Rockwood North Cancer Treatment Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Spokane Valley

Rockwood Clinic Cancer Treatment Center-Valley

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Tacoma

Franciscan Research Center-Northwest Medical Plaza

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Northwest Medical Specialties PLLC

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Vancouver

PeaceHealth Southwest Medical Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Walla Walla

Providence Saint Mary Regional Cancer Center

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Yelm

Providence Regional Cancer System-Yelm

Keith S. Lanier
Ph: 503-215-2614
Email: CanRsrchStudies@providence.org

Keith S. Lanier
Principal Investigator

Wisconsin
Appleton

ThedaCare Regional Cancer Center

Matthias Weiss
Ph: 920-380-1500

Matthias Weiss
Principal Investigator

Burlington

Aurora Cancer Care-Burlington

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Eau Claire

Marshfield Clinic Cancer Center at Sacred Heart

Rezwan Islam
Ph: 715-393-1400

Rezwan Islam
Principal Investigator

Elkhorn

Aurora Cancer Care-Southern Lakes

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Fond Du Lac

Aurora Health Center-Fond du Lac

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Germantown

Aurora Health Care Germantown Health Center

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Grafton

Aurora Cancer Care-Grafton

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Green Bay

Aurora BayCare Medical Center

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Kenosha

Aurora Cancer Care-Kenosha South

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

La Crosse

Mayo Clinic Health System-Franciscan Healthcare

Paula Gill
Ph: 855-776-0015

Paula Gill
Principal Investigator

Marinette

Vince Lombardi Cancer Clinic-Marinette

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Marshfield

Marshfield Clinic

Rezwan Islam
Ph: 715-393-1400

Rezwan Islam
Principal Investigator

Milwaukee

Aurora Cancer Care-Milwaukee

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Aurora Cancer Care-Milwaukee South

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Aurora Saint Luke's Medical Center

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Aurora Sinai Medical Center

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Minocqua

Marshfield Clinic-Minocqua Center

Rezwan Islam
Ph: 715-393-1400

Rezwan Islam
Principal Investigator

Oshkosh

Vince Lombardi Cancer Clinic - Oshkosh

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Racine

Aurora Cancer Care-Racine

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Rice Lake

Marshfield Clinic-Rice Lake Center

Rezwan Islam
Ph: 715-393-1400

Rezwan Islam
Principal Investigator

Sheboygan

Vince Lombardi Cancer Clinic-Sheboygan

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Stevens Point

Marshfield Clinic Cancer Care at Saint Michael's Hospital

Rezwan Islam
Ph: 715-393-1400

Rezwan Islam
Principal Investigator

Summit

Aurora Medical Center in Summit

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Two Rivers

Vince Lombardi Cancer Clinic

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Wausau

Marshfield Clinic-Wausau Center

Rezwan Islam
Ph: 715-393-1400

Rezwan Islam
Principal Investigator

Wauwatosa

Aurora Cancer Care-Milwaukee West

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

West Allis

Aurora West Allis Medical Center

Rubina Qamar
Ph: 888-709-2080

Rubina Qamar
Principal Investigator

Weston

Marshfield Clinic - Weston Center

Rezwan Islam
Ph: 715-393-1400

Rezwan Islam
Principal Investigator

Wisconsin Rapids

Marshfield Clinic - Wisconsin Rapids Center

Rezwan Islam
Ph: 715-393-1400

Rezwan Islam
Principal Investigator

Wyoming
Cody

Billings Clinic-Cody

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Sheridan

Welch Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT01573442

Note: Information about participating sites on pharmaceutical industry trials may be incomplete. Please visit the ClinicalTrials.gov record via the link above for more information about participating sites.