Standard or Comprehensive Radiation Therapy in Treating Patients with Early-Stage Breast Cancer Previously Treated with Chemotherapy and Surgery

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Basic Trial Information

PhaseTypeStatusAgeTrial IDs
Phase IIIBiomarker/Laboratory analysis, TreatmentActive18 and overNSABP-B-51
NCI-2012-03198, NSABP-B-51/RTOG-1304, NCT01872975

Trial Description

Summary

This randomized phase III trial studies radiation therapy to the breast, chest wall and lymph nodes (comprehensive) compared to standard radiation therapy to the breast in treating patients with early-stage breast cancer previously treated with chemotherapy and surgery. Radiation therapy uses high-energy x rays to kill tumor cells. It is not yet known whether comprehensive radiation therapy is more effective than standard radiation therapy in treating patients with early-stage breast cancer.

Further Study Information

PRIMARY OBJECTIVES:

I. To evaluate whether the addition of chest wall + regional nodal radiation therapy (XRT) after mastectomy or breast + regional nodal XRT after breast conserving surgery will significantly reduce the rate of events for invasive breast cancer recurrence-free interval (IBC-RFI) in patients who present with histologically positive axillary nodes but convert to histologically negative axillary nodes following neoadjuvant chemotherapy.

SECONDARY OBJECTIVES:

I. To evaluate whether the addition of chest wall + regional nodal XRT after mastectomy or breast + regional nodal XRT after breast conserving surgery will significantly prolong overall survival (OS) in patients who present with histologically positive axillary nodes but convert to histologically negative axillary nodes following neoadjuvant chemotherapy.

II. To evaluate whether the addition of chest wall + regional nodal XRT after mastectomy or breast + regional nodal XRT after breast conserving surgery will significantly reduce the rates of events for local-regional recurrence-free interval (LRRFI) in patients who present with histologically positive axillary nodes but convert to histologically negative axillary nodes following neoadjuvant chemotherapy.

III. To evaluate whether the addition of chest wall + regional nodal XRT after mastectomy or breast + regional nodal XRT after breast conserving surgery will significantly reduce the rate of events for distant recurrence-free interval (DRFI) in patients who present with histologically positive axillary nodes but convert to histologically negative axillary nodes following neoadjuvant chemotherapy.

IV. To compare the rates of disease-free survival (DFS)-ductal carcinoma in situ (DCIS) by treatment arm.

V. To compare the rates of second primary cancer by treatment arm.

VI. To compare the effect of adding XRT on the cosmetic outcomes in mastectomy patients who have had reconstruction.

VII. To compare the effect of adding XRT on quality of life including arm problems, lymphedema, pain, and fatigue.

VIII. To evaluate the toxicity associated with each of the radiation therapy regimens.

IX. To determine whether computed tomography (CT)-based conformal methods (intensity-modulated radiation therapy [IMRT] and 3-dimensional conformal radiation therapy [3DCRT]) for chest-wall + regional nodal XRT post mastectomy and regional nodal XRT with breast XRT following breast conserving surgery are feasible in a multi-institutional setting and whether dose-volume analyses can be established to assess treatment adequacy and to develop normal tissue complication probabilities (NTCP) for the likelihood of toxicity.

X. To compare the effect of XRT in patients receiving mastectomy and in patients receiving lumpectomy.

XI. To examine the role of proliferation measures as a prognosticator for patients with residual disease after neoadjuvant chemotherapy.

XII. To develop predictors of the degree of reduction in local regional recurrence (LRR).

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients are assigned to 1 of 2 treatment groups.

GROUP IA: Lumpectomy patients undergo whole breast radiation therapy using IMRT or 3D-CRT once daily (QD) 5 days a week for 5 weeks followed by a radiation therapy boost to the lumpectomy cavity once daily 5 days a week for 1-1/2 weeks.

GROUP IB: Mastectomy patients do not undergo radiation therapy.

ARM II: Patients are assigned to 1 of 2 treatment groups.

GROUP IIA: Lumpectomy patients undergo regional nodal radiation therapy with whole breast radiation therapy using IMRT or 3D-CRT QD 5 days a week for 5 weeks followed by a radiation therapy boost to the lumpectomy cavity QD 5 days a week for 1-1/2 weeks.

GROUP IIB: Mastectomy patients undergo regional nodal radiation therapy using IMRT or 3D-CRT QD 5 days a week for 5 weeks.

All patients also receive systemic therapy as planned (hormonal therapy for patients with hormone-receptor positive breast cancer and trastuzumab or other anti-human epidermal growth factor receptor 2 [HER2] therapy for patients with breast cancer that is HER2-positive).

After completion of study treatment, patients are followed up at 6, 12, 18, and 24 months and then yearly for 8 years.

Eligibility Criteria

Inclusion Criteria:

The patient must have signed and dated an Institutional Review Board (IRB)-approved consent form that conforms to federal and institutional guidelines

The patient must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 or 1

Patient must have clinically T1-3, N1 breast cancer at the time of diagnosis (before neoadjuvant therapy); clinical axillary nodal involvement can be assessed by palpation, ultrasound, CT scan, magnetic resonance imaging (MRI), positron emission tomography (PET) scan, or PET/CT scan

Patient must have had pathologic confirmation of axillary nodal involvement at presentation (before neoadjuvant therapy) based on either a positive fine needle aspirate (FNA) (demonstrating malignant cells) or positive core needle biopsy (demonstrating invasive adenocarcinoma); the FNA or core needle biopsy can be performed either by palpation or by image guidance; documentation of axillary nodal positivity by sentinel node biopsy (before neoadjuvant therapy) is not permitted

Patients must have had estrogen receptor (ER) analysis performed on the primary breast tumor before neoadjuvant therapy according to current American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) guideline recommendations for hormone receptor testing; if negative for ER, assessment of progesterone receptor (PgR) must also be performed according to current ASCO/CAP guideline recommendations for hormone receptor testing

Patients must have had HER2 testing performed on the primary breast tumor before neoadjuvant chemotherapy according to the current ASCO/CAP guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer; patients who have a primary tumor that is either HER2-positive or HER2-negative are eligible

Patient must have completed a minimum of 8 weeks of standard neoadjuvant chemotherapy consisting of an anthracycline and/or taxane-based regimen

For patients who receive adjuvant chemotherapy after surgery, a maximum of 12 weeks of intended chemotherapy may be administered but must be completed before randomization; (if treatment delays occur, chemotherapy must be completed within 14 weeks); the dose and schedule of the adjuvant chemotherapy are at the investigator's discretion; Note: it is preferred that all intended chemotherapy be administered in the neoadjuvant setting

Patients with HER2-positive tumors must have received neoadjuvant anti-HER2 therapy (either with all or with a portion of the neoadjuvant chemotherapy regimen), unless medically contraindicated

At the time of definitive surgery, all removed axillary nodes must be histologically free from cancer; acceptable procedures for assessment of axillary nodal status at the time of surgery include:

Axillary node dissection

Sentinel node biopsy alone provided that at least 2 sentinel lymph nodes are removed; removal of at least 3 sentinel lymph nodes and use of dual tracer for lymphatic mapping are strongly recommended or

Sentinel node biopsy followed by axillary node dissection

Note: patients are eligible whether there is residual invasive carcinoma in the surgical breast specimen or whether there is evidence of pathologic complete response; patients who are found to be pathologically node-positive at the time of surgery, based on sentinel node biopsy alone, are candidates for A011202, a study developed by the Alliance in Oncology, an National Cancer Institute (NCI) Cooperative Group; if A011202 is open at the investigator's institution, patients should be approached about participating in the A011202 study

Patients with pathologic staging of ypN0(i+) or ypN0(mol+) are eligible

Patient who have undergone either a total mastectomy or a lumpectomy are eligible; (patients who have had a nipple-sparing mastectomy are eligible)

For patients who undergo lumpectomy, the margins of the resected specimen or re-excision must be histologically free of invasive tumor and DCIS as determined by the local pathologist; additional operative procedures may be performed to obtain clear margins; if tumor is still present at the resected margin after re-excision(s), the patient must undergo total mastectomy to be eligible; (patients with margins positive for lobular carcinoma in situ [LCIS] are eligible without additional resection)

For patients who undergo mastectomy, the margins must be histologically free of residual (microscopic or gross) tumor

The interval between the last surgery for breast cancer (including re-excision of margins) and randomization must be no more than 70 days; also, if adjuvant chemotherapy was administered, the interval between the last chemotherapy treatment and randomization must be no more than 70 days

The patient must have recovered from surgery with the incision completely healed and no signs of infection

If adjuvant chemotherapy was administered, chemotherapy-related toxicity that may interfere with delivery of radiation therapy should have resolved

Exclusion Criteria:

Definitive clinical or radiologic evidence of metastatic disease

T4 tumors including inflammatory breast cancer

Documentation of axillary nodal positivity before neoadjuvant therapy by sentinel node biopsy alone

N2 or N3 disease detected clinically or by imaging

Patients with histologically positive axillary nodes post neoadjuvant therapy

Patients with microscopic positive margins after definitive surgery

Synchronous or previous contralateral invasive breast cancer or DCIS; (patients with synchronous and/or previous contralateral LCIS are eligible)

Any prior history, not including the index cancer, of ipsilateral invasive breast cancer or ipsilateral DCIS treated with radiation therapy; (patients with synchronous or previous ipsilateral LCIS are eligible)

History of non-breast malignancies (except for in situ cancers treated only by local excision and basal cell and squamous cell carcinomas of the skin) within 5 years prior to randomization

Any radiation therapy for the currently diagnosed breast cancer prior to randomization

Any continued use of sex hormonal therapy, e.g., birth control pills, ovarian hormone replacement therapy; patients are eligible if these medications are discontinued prior to randomization

Prior breast or thoracic radiation therapy (RT) for any condition

Active collagen vascular disease, specifically dermatomyositis with a creatinine phosphokinase (CPK) level above normal or with an active skin rash, systemic lupus erythematosus, or scleroderma

Pregnancy or lactation at the time of study entry; (Note: pregnancy testing must be performed within 2 weeks prior to randomization according to institutional standards for women of childbearing potential)

Other non-malignant systemic disease that would preclude the patient from receiving study treatment or would prevent required follow-up

Psychiatric or addictive disorders or other conditions that, in the opinion of the investigator, would preclude the patient from meeting the study requirements

Trial Contact Information

Trial Lead Organizations / Sponsors / Collaborators

NRG Oncology

  • National Cancer Institute
Eleftherios (Terry) Paul Mamounas, Principal Investigator

Trial Sites

U.S.A.

Alabama
Birmingham

University of Alabama at Birmingham Cancer Center

Jennifer F. De Los Santos
Ph: 800-828-8816

Jennifer F. De Los Santos
Principal Investigator

Mobile

University of South Alabama Mitchell Cancer Institute

Weisi Yan
Ph: 251-445-9870
Email: pfrancisco@usouthal.edu

Weisi Yan
Principal Investigator

Alaska
Anchorage

Providence Alaska Medical Center

Benjamin Buckner Bridges
Ph: 208-381-3376
Email: mcdonagd@slhs.org

Benjamin Buckner Bridges
Principal Investigator

Arizona
Gilbert

Arizona Breast Cancer Specialists-Gilbert

Robert R. Kuske
Ph: 480-922-4600

Robert R. Kuske
Principal Investigator

Peoria

Arizona Center for Cancer Care-Peoria

Robert R. Kuske
Ph: 480-922-4600

Robert R. Kuske
Principal Investigator

Phoenix

Arizona Breast Cancer Specialists-Phoenix

Robert R. Kuske
Ph: 480-922-4600

Robert R. Kuske
Principal Investigator

Scottsdale

Arizona Breast Cancer Specialists-Scottsdale

Robert R. Kuske
Ph: 480-922-4600

Robert R. Kuske
Principal Investigator

Surprise

Arizona Center for Cancer Care-Surprise

Robert R. Kuske
Ph: 480-922-4600

Robert R. Kuske
Principal Investigator

Tucson

Arizona Oncology Associates-West Orange Grove

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Arkansas
Little Rock

University of Arkansas for Medical Sciences

V. Suzanne Klimberg
Ph: 501-686-8274

V. Suzanne Klimberg
Principal Investigator

California
Auburn

Sutter Cancer Centers Radiation Oncology Services-Auburn

Stacy D. D'Andre
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stacy D. D'Andre
Principal Investigator

Bakersfield

AIS Cancer Center at San Joaquin Community Hospital

Jyoti S. Mayadev
Ph: 916-734-3089

Jyoti S. Mayadev
Principal Investigator

Burlingame

Mills - Peninsula Hospitals

Stacy D. D'Andre
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stacy D. D'Andre
Principal Investigator

Cameron Park

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

Stacy D. D'Andre
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stacy D. D'Andre
Principal Investigator

Castro Valley

Eden Hospital Medical Center

Stacy D. D'Andre
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stacy D. D'Andre
Principal Investigator

Duarte

City of Hope Comprehensive Cancer Center

Lily Lau Lai
Ph: 800-826-4673
Email: becomingapatient@coh.org

Lily Lau Lai
Principal Investigator

Dublin

Epic Care-Dublin

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Emeryville

Epic Care Partners in Cancer Care

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Fresno

California Cancer Center - North Fresno

Uma G. Swamy
Ph: 559-447-4050

Uma G. Swamy
Principal Investigator

La Jolla

UC San Diego Moores Cancer Center

Anne Marie Duquette Wallace
Ph: 858-822-5354
Email: cancercto@ucsd.edu

Anne Marie Duquette Wallace
Principal Investigator

Lancaster

City of Hope Antelope Valley

Lily Lau Lai
Ph: 800-826-4673
Email: becomingapatient@coh.org

Lily Lau Lai
Principal Investigator

Loma Linda

Loma Linda University Medical Center

Sharon Shou Jen Lum
Ph: 909-558-3375

Sharon Shou Jen Lum
Principal Investigator

Los Angeles

Cedars Sinai Medical Center

Christiane Michele J Burnison
Ph: 310-423-8965

Christiane Michele J Burnison
Principal Investigator

Los Angeles County-USC Medical Center

Naomi Rachel Schechter
Ph: 323-865-0451

Naomi Rachel Schechter
Principal Investigator

USC / Norris Comprehensive Cancer Center

Naomi Rachel Schechter
Ph: 323-865-0451

Naomi Rachel Schechter
Principal Investigator

Newport Beach

Hoag Memorial Hospital

Peter V. Chen
Ph: 949-722-6237
Email: HoagCancerCenter@hoag.org

Peter V. Chen
Principal Investigator

Oakland

Alta Bates Summit Medical Center - Summit Campus

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Kaiser Permanente Oakland-Broadway

Louis Fehrenbacher
Ph: 626-564-3455

Louis Fehrenbacher
Principal Investigator

Orange

Saint Joseph Hospital - Orange

David Andrew Margileth
Ph: 714-734-6220

David Andrew Margileth
Principal Investigator

UC Irvine Health/Chao Family Comprehensive Cancer Center

Parima Daroui
Ph: 877-827-8839
Email: ucstudy@uci.edu

Parima Daroui
Principal Investigator

Palm Springs

Desert Regional Medical Center

Amir Lavaf
Ph: 760-416-4730

Amir Lavaf
Principal Investigator

Pasadena

Huntington Memorial Hospital

Ruth Chandler Williamson
Ph: 626-535-2420

Ruth Chandler Williamson
Principal Investigator

Pomona

Pomona Valley Hospital Medical Center

Yallapragada S. (Ram) Rao
Ph: 909-865-9555

Yallapragada S. (Ram) Rao
Principal Investigator

Rancho Cordova

Kaiser Permanente-Rancho Cordova Cancer Center

Louis Fehrenbacher
Ph: 626-564-3455

Louis Fehrenbacher
Principal Investigator

Rohnert Park

Rohnert Park Cancer Center

Louis Fehrenbacher
Ph: 626-564-3455

Louis Fehrenbacher
Principal Investigator

Roseville

Kaiser Permanente-Roseville

Louis Fehrenbacher
Ph: 626-564-3455

Louis Fehrenbacher
Principal Investigator

Sutter Cancer Centers Radiation Oncology Services-Roseville

Stacy D. D'Andre
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stacy D. D'Andre
Principal Investigator

Sutter Roseville Medical Center

Stacy D. D'Andre
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stacy D. D'Andre
Principal Investigator

The Permanente Medical Group-Roseville Radiation Oncology

Louis Fehrenbacher
Ph: 626-564-3455

Louis Fehrenbacher
Principal Investigator

Sacramento

Sutter General Hospital

Stacy D. D'Andre
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stacy D. D'Andre
Principal Investigator

University of California Davis Comprehensive Cancer Center

Jyoti S. Mayadev
Ph: 916-734-3089

Jyoti S. Mayadev
Principal Investigator

Saint Helena

Saint Helena Hospital

Gregory B. Smith
Ph: 707-967-3698

Gregory B. Smith
Principal Investigator

San Diego

Naval Medical Center -San Diego

Harvey Bernard Wilds
Ph: 619-532-8712

Harvey Bernard Wilds
Principal Investigator

Santa Clara

Kaiser Permanente Medical Center - Santa Clara

Louis Fehrenbacher
Ph: 626-564-3455

Louis Fehrenbacher
Principal Investigator

South Pasadena

City of Hope South Pasadena

Lily Lau Lai
Ph: 800-826-4673
Email: becomingapatient@coh.org

Lily Lau Lai
Principal Investigator

South San Francisco

Kaiser Permanente Cancer Treatment Center

Louis Fehrenbacher
Ph: 626-564-3455

Louis Fehrenbacher
Principal Investigator

Truckee

Gene Upshaw Memorial Tahoe Forest Cancer Center

Jyoti S. Mayadev
Ph: 916-734-3089

Jyoti S. Mayadev
Principal Investigator

Vacaville

Sutter Cancer Centers Radiation Oncology Services-Vacaville

Stacy D. D'Andre
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stacy D. D'Andre
Principal Investigator

Vallejo

Sutter Solano Medical Center/Cancer Center

Stacy D. D'Andre
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Stacy D. D'Andre
Principal Investigator

Colorado
Aurora

Rocky Mountain Cancer Centers-Aurora

Keren Sturtz
Ph: 303-777-2663
Email: ccrp@co-cancerresearch.org

Keren Sturtz
Principal Investigator

University of Colorado Cancer Center - Anschutz Cancer Pavilion

Rachel Abrams Rabinovitch
Ph: 720-848-0650

Rachel Abrams Rabinovitch
Principal Investigator

Boulder

Rocky Mountain Cancer Centers-Boulder

Keren Sturtz
Ph: 303-777-2663
Email: ccrp@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Colorado Springs

Memorial Hospital-Center

Rachel Abrams Rabinovitch
Ph: 720-848-0650

Rachel Abrams Rabinovitch
Principal Investigator

Penrose-Saint Francis Healthcare

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Denver

Porter Adventist Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Edwards

The Shaw Regional Cancer Center

Patricia Harrigan Hardenbergh
Ph: 970-569-7429

Patricia Harrigan Hardenbergh
Principal Investigator

Fort Collins

Poudre Valley Hospital

Rachel Abrams Rabinovitch
Ph: 720-848-0650

Rachel Abrams Rabinovitch
Principal Investigator

Littleton

Rocky Mountain Cancer Centers-Littleton

Keren Sturtz
Ph: 303-777-2663
Email: ccrp@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Pueblo

Saint Mary Corwin Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Thornton

Rocky Mountain Cancer Centers-Thornton

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Wheat Ridge

SCL Health Lutheran Medical Center

Keren Sturtz
Ph: 303-777-2663
Email: ccrp@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Connecticut
Hartford

Hartford Hospital

Helaine F. Bertsch
Ph: 860-545-5363

Helaine F. Bertsch
Principal Investigator

Middletown

Middlesex Hospital

Susanna Hong
Ph: 860-358-2058

Susanna Hong
Principal Investigator

New Britain

The Hospital of Central Connecticut

Neal B. Goldberg
Ph: 860-224-5660

Neal B. Goldberg
Principal Investigator

Delaware
Newark

Christiana Care Health System-Christiana Hospital

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Helen F Graham Cancer Center

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

District of Columbia
Washington

MedStar Georgetown University Hospital

Edward C. McCarron
Ph: 443-777-7364

Edward C. McCarron
Principal Investigator

MedStar Washington Hospital Center

Edward C. McCarron
Ph: 443-777-7364

Edward C. McCarron
Principal Investigator

Sibley Memorial Hospital

Jean Lundberg Wright
Ph: 202-243-2373

Jean Lundberg Wright
Principal Investigator

Florida
Altamonte Springs

Florida Hospital Cancer Institute Altamonte

Carlos Alberto Alemany
Ph: 407-303-2090
Email: FH.Cancer.Research@flhosp.org

Carlos Alberto Alemany
Principal Investigator

Atlantis

John Fitzgerald Kennedy Medical Center

Beth-Ann Lesnikoski
Ph: 561-964-2662

Beth-Ann Lesnikoski
Principal Investigator

Clearwater

Morton Plant Hospital

Peter William Blumencranz
Ph: 727-461-8519

Peter William Blumencranz
Principal Investigator

Deerfield Beach

UM Sylvester Comprehensive Cancer Center at Deerfield Beach

Cristiane Takita
Ph: 305-243-2647

Cristiane Takita
Principal Investigator

Gainesville

University of Florida

Judith L. Lightsey
Ph: 352-273-8675
Email: trials@cancer.ufl.edu

Judith L. Lightsey
Principal Investigator

Hollywood

Memorial Regional Hospital/Joe DiMaggio Children's Hospital

Srinath Sundararaman
Ph: 954-265-2234

Srinath Sundararaman
Principal Investigator

Miami

Jackson Memorial Hospital-Holtz Children's Hospital

Cristiane Takita
Ph: 305-243-2647

Cristiane Takita
Principal Investigator

University of Miami Miller School of Medicine-Sylvester Cancer Center

Cristiane Takita
Ph: 305-243-2647

Cristiane Takita
Principal Investigator

Orlando

Florida Hospital Orlando

Carlos Alberto Alemany
Ph: 407-303-2090
Email: FH.Cancer.Research@flhosp.org

Carlos Alberto Alemany
Principal Investigator

UF Cancer Center at Orlando Health

Tomas Dvorak
Ph: 321-841-7246
Email: CancerClinicalTrials@orlandohealth.com

Tomas Dvorak
Principal Investigator

Tampa

Moffitt Cancer Center

Roberto Diaz
Ph: 800-456-7121
Email: canceranswers@moffitt.org

Roberto Diaz
Principal Investigator

Saint Joseph's Hospital/Children's Hospital-Tampa

Robert Charles Gabordi
Ph: 800-882-4123

Robert Charles Gabordi
Principal Investigator

Georgia
Atlanta

Piedmont Hospital

Adam Wayne Nowlan
Ph: 404-425-7943
Email: ORS@piedmont.org

Adam Wayne Nowlan
Principal Investigator

Carrollton

Tanner Medical Center/Carrollton

James Richard Bland
Ph: 770-836-9824

James Richard Bland
Principal Investigator

Decatur

Dekalb Medical Center

Sharad Anant Ghamande
Ph: 706-721-1663
Email: cancer@augusta.edu

Sharad Anant Ghamande
Principal Investigator

Savannah

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

John A. Pablo
Ph: 912-819-5704

John A. Pablo
Principal Investigator

Memorial University Medical Center

Harvey Charles Lebos
Ph: 912-354-6187

Harvey Charles Lebos
Principal Investigator

Hawaii
Ewa Beach

The Cancer Center of Hawaii-Leeward

Kenneth N.M. Sumida
Ph: 808-524-6115

Kenneth N.M. Sumida
Principal Investigator

Honolulu

Queen's Medical Center

Kenneth N.M. Sumida
Ph: 808-524-6115

Kenneth N.M. Sumida
Principal Investigator

The Cancer Center of Hawaii-Liliha

Kenneth N.M. Sumida
Ph: 808-524-6115

Kenneth N.M. Sumida
Principal Investigator

Idaho
Boise

Saint Alphonsus Cancer Care Center-Boise

Samir Narayan
Ph: 734-712-4673

Samir Narayan
Principal Investigator

Post Falls

Kootenai Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Illinois
Chicago

Advocate Illinois Masonic Medical Center

Santosh V. Yajnik
Ph: 773-296-5360

Santosh V. Yajnik
Principal Investigator

John H Stroger Jr Hospital of Cook County

Thomas E. Lad
Ph: 312-864-6000

Thomas E. Lad
Principal Investigator

Mount Sinai Hospital Medical Center

Pam G. Khosla
Ph: 773-257-5960
Email: suhi@sinai.org

Pam G. Khosla
Principal Investigator

Northwestern University

Eric D. Donnelly
Ph: 312-695-1301
Email: cancer@northwestern.edu

Eric D. Donnelly
Principal Investigator

University of Chicago Comprehensive Cancer Center

Steven J. Chmura
Ph: 773-834-7424

Steven J. Chmura
Principal Investigator

University of Illinois

Kent F. Hoskins
Ph: 312-355-3046

Kent F. Hoskins
Principal Investigator

Decatur

Decatur Memorial Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Elk Grove Village

AMITA Health Alexian Brothers Medical Center

Kevin Patrick McKian
Ph: 847-952-7164
Email: fredianc@alexian.net

Kevin Patrick McKian
Principal Investigator

Elmhurst

Elmhurst Memorial Hospital

Vasudha Lingareddy
Ph: 630-646-6075

Vasudha Lingareddy
Principal Investigator

Evanston

NorthShore University HealthSystem-Evanston Hospital

Elaine Lee Wade
Ph: 847-570-2109

Elaine Lee Wade
Principal Investigator

Glenview

NorthShore University HealthSystem-Glenbrook Hospital

Elaine Lee Wade
Ph: 847-570-2109

Elaine Lee Wade
Principal Investigator

Hazel Crest

Advocate South Suburban Hospital

Elke Aippersbach
Ph: 800-323-8622

Elke Aippersbach
Principal Investigator

Highland Park

NorthShore University HealthSystem-Highland Park Hospital

Elaine Lee Wade
Ph: 847-570-2109

Elaine Lee Wade
Principal Investigator

Kankakee

Presence Saint Mary's Hospital

Sylvia V. Velinova Falls
Ph: 815-937-8780

Sylvia V. Velinova Falls
Principal Investigator

Lake Forest

Northwestern Medicine Lake Forest Hospital

Eric D. Donnelly
Ph: 312-695-1301
Email: cancer@northwestern.edu

Eric D. Donnelly
Principal Investigator

Libertyville

Condell Memorial Hospital

Dean J. Conterato
Ph: 630-929-6129
Email: advocateresearch@advocatehealth.com

Dean J. Conterato
Principal Investigator

Maywood

Loyola University Medical Center

Tarita O. Thomas
Ph: 708-226-4357

Tarita O. Thomas
Principal Investigator

Naperville

Edward Hospital/Cancer Center

Vasudha Lingareddy
Ph: 630-646-6075

Vasudha Lingareddy
Principal Investigator

New Lenox

UC Comprehensive Cancer Center at Silver Cross

Steven J. Chmura
Ph: 773-834-7424

Steven J. Chmura
Principal Investigator

Oak Lawn

Advocate Christ Medical Center

Paul Duncan Crossan
Ph: 800-323-8622
Email: paul.crossan@advocatehealth.com

Paul Duncan Crossan
Principal Investigator

Park Ridge

Advocate Lutheran General Hospital

Jacob David Bitran
Ph: 847-384-3621

Jacob David Bitran
Principal Investigator

Peoria

Illinois CancerCare-Peoria

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Radiation Oncology at Peoria Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Plainfield

Edward Hospital/Cancer Center?Plainfield

Vasudha Lingareddy
Ph: 630-646-6075

Vasudha Lingareddy
Principal Investigator

Rockford

SwedishAmerican Regional Cancer Center/ACT

Harvey E. Einhorn
Ph: 779-696-9400
Email: cancercare@swedishamerican.org

Harvey E. Einhorn
Principal Investigator

Springfield

Memorial Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Urbana

Carle Cancer Center

Sinisa Stanic
Ph: 800-446-5532

Sinisa Stanic
Principal Investigator

Indiana
Anderson

Saint Vincent Anderson Regional Hospital/Cancer Center

Alexander M. Yeh
Ph: 765-646-8358

Alexander M. Yeh
Principal Investigator

Fort Wayne

Parkview Hospital Randallia

Brian K. Chang
Ph: 260-373-8888
Email: parkviewresearch@parkview.com

Brian K. Chang
Principal Investigator

Goshen

Goshen Center for Cancer Care

Laura L. Morris
Ph: 574-364-2973
Email: cccois@goshenhealth.com

Laura L. Morris
Principal Investigator

Indianapolis

Community Cancer Center East

Shih Jack Wei
Ph: 317-497-2823
Email: lcheri@ecommunity.com

Shih Jack Wei
Principal Investigator

Community Cancer Center North

Shih Jack Wei
Ph: 317-497-2823
Email: lcheri@ecommunity.com

Shih Jack Wei
Principal Investigator

Community Cancer Center South

Shih Jack Wei
Ph: 317-497-2823
Email: lcheri@ecommunity.com

Shih Jack Wei
Principal Investigator

Franciscan Health Indianapolis

Subhash C. Sharma
Ph: 317-528-7060

Subhash C. Sharma
Principal Investigator

Saint Vincent Hospital and Health Care Center

Alexander M. Yeh
Ph: 765-646-8358

Alexander M. Yeh
Principal Investigator

South Bend

Memorial Hospital of South Bend

Thomas Joseph Reid
Ph: 800-284-7370

Thomas Joseph Reid
Principal Investigator

Iowa
Clive

Mercy Cancer Center-West Lakes

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Des Moines

Iowa Methodist Medical Center

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Mercy Medical Center - Des Moines

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Kansas
Kansas City

University of Kansas Cancer Center

Melissa Pulfer Mitchell
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Melissa Pulfer Mitchell
Principal Investigator

Overland Park

University of Kansas Cancer Center-Overland Park

Melissa Pulfer Mitchell
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Melissa Pulfer Mitchell
Principal Investigator

Wichita

Via Christi Regional Medical Center

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Wesley Medical Center

Shaker R. Dakhil
Ph: 316-268-5374

Shaker R. Dakhil
Principal Investigator

Kentucky
Edgewood

Saint Elizabeth Medical Center South

Lauren Elizabeth Castellini
Ph: 859-301-5473
Email: darla.hehman@stelizabeth.com

Lauren Elizabeth Castellini
Principal Investigator

Fort Thomas

Saint Elizabeth Fort Thomas

Lauren Elizabeth Castellini
Ph: 859-301-5473
Email: darla.hehman@stelizabeth.com

Lauren Elizabeth Castellini
Principal Investigator

Louisville

Baptist Health Louisville

James B. Eckman
Ph: 859-260-6425

James B. Eckman
Principal Investigator

Norton Hospital Pavilion and Medical Campus

Mark Stephen Cornett
Ph: 502-629-2500

Mark Stephen Cornett
Principal Investigator

Norton Suburban Hospital and Medical Campus

Mark Stephen Cornett
Ph: 502-629-2500

Mark Stephen Cornett
Principal Investigator

The James Graham Brown Cancer Center at University of Louisville

Anthony Edward Dragun
Ph: 866-530-5516

Anthony Edward Dragun
Principal Investigator

Owensboro

Owensboro Health Mitchell Memorial Cancer Center

Samuel Ryan Faught
Ph: 270-688-3691
Email: shawns@omhs.org

Samuel Ryan Faught
Principal Investigator

Louisiana
Baton Rouge

Baton Rouge General Medical Center

Bridgette M. Collins-Burow
Ph: 504-988-6121

Bridgette M. Collins-Burow
Principal Investigator

Mary Bird Perkins Cancer Center

David S. Hanson
Ph: 225-215-1353
Email: clinicalresearch@marybird.com

David S. Hanson
Principal Investigator

Woman's Hospital

M. Giles Fort
Ph: 225-231-5296
Email: Ericka.Seidemann@womans.org

M. Giles Fort
Principal Investigator

Covington

Mary Bird Cancer Center/Saint Tammany Parish

David S. Hanson
Ph: 225-215-1353
Email: clinicalresearch@marybird.com

David S. Hanson
Principal Investigator

Houma

Mary Bird Perkins Cancer Center/Terrebonne General Medical Center

David S. Hanson
Ph: 225-215-1353
Email: clinicalresearch@marybird.com

David S. Hanson
Principal Investigator

Kenner

Ochsner Medical Center Kenner

Mini J. Elnaggar
Ph: 888-562-4763

Mini J. Elnaggar
Principal Investigator

New Orleans

Ochsner Medical Center Jefferson

Mini J. Elnaggar
Ph: 888-562-4763

Mini J. Elnaggar
Principal Investigator

Maine
Bangor

Eastern Maine Medical Center

Thomas H. Openshaw
Ph: 800-987-3005

Thomas H. Openshaw
Principal Investigator

Scarborough

Maine Medical Center- Scarborough Campus

Matthew D. Cheney
Ph: 207-885-7565

Matthew D. Cheney
Principal Investigator

Maryland
Annapolis

Anne Arundel Medical Center

Mary E. Young
Ph: 443-481-1320
Email: kbodenhorn@aahs.org

Mary E. Young
Principal Investigator

Baltimore

Greater Baltimore Medical Center

Geoffrey Alexander Neuner
Ph: 443-849-3706

Geoffrey Alexander Neuner
Principal Investigator

Johns Hopkins University/Sidney Kimmel Cancer Center

Jean Lundberg Wright
Ph: 202-243-2373

Jean Lundberg Wright
Principal Investigator

MedStar Franklin Square Medical Center/Weinberg Cancer Institute

Edward C. McCarron
Ph: 443-777-7364

Edward C. McCarron
Principal Investigator

University of Maryland/Greenebaum Cancer Center

Steven J. Feigenberg
Ph: 800-888-8823

Steven J. Feigenberg
Principal Investigator

Columbia

Central Maryland Radiation Oncology in Howard County

Steven J. Feigenberg
Ph: 800-888-8823

Steven J. Feigenberg
Principal Investigator

Glen Burnie

Tate Cancer Center

Steven J. Feigenberg
Ph: 800-888-8823

Steven J. Feigenberg
Principal Investigator

Massachusetts
Boston

Boston Medical Center

Ariel Elysse Hirsch
Ph: 617-638-8265

Ariel Elysse Hirsch
Principal Investigator

Dana-Farber Cancer Institute

Faina Nakhlis
Ph: 617-983-7000

Faina Nakhlis
Principal Investigator

Fall River

Saint Anne's Hospital

John Li-Hsiang Yang
Ph: 508-674-5600

John Li-Hsiang Yang
Principal Investigator

Lowell

Lowell General Hospital

Matthew Strauss Katz
Ph: 978-788-7084
Email: ghincks@lowellgeneral.org

Matthew Strauss Katz
Principal Investigator

Springfield

Baystate Medical Center

Seth A. Kaufman
Ph: 413-794-9338

Seth A. Kaufman
Principal Investigator

Michigan
Brownstown

Henry Ford Cancer Institute¿Downriver

Thomas J. Doyle
Ph: 313-916-1784

Thomas J. Doyle
Principal Investigator

Clarkston

21st Century Oncology-Clarkston

Frank A. Vicini
Ph: 888-326-9729

Frank A. Vicini
Principal Investigator

Clinton Township

Henry Ford Macomb Hospital-Clinton Township

Thomas J. Doyle
Ph: 313-916-1784

Thomas J. Doyle
Principal Investigator

Dearborn

Beaumont Hospital-Dearborn

Samir Narayan
Ph: 734-712-4673

Samir Narayan
Principal Investigator

Detroit

Henry Ford Hospital

Thomas J. Doyle
Ph: 313-916-1784

Thomas J. Doyle
Principal Investigator

Saint John Hospital and Medical Center

Samir Narayan
Ph: 734-712-4673

Samir Narayan
Principal Investigator

Wayne State University/Karmanos Cancer Institute

Jordan M. Maier
Ph: 313-576-9363

Jordan M. Maier
Principal Investigator

Farmington Hills

21st Century Oncology-Farmington Hills

Frank A. Vicini
Ph: 888-326-9729

Frank A. Vicini
Principal Investigator

Flint

Genesys Hurley Cancer Institute

Samir Narayan
Ph: 734-712-4673

Samir Narayan
Principal Investigator

Hurley Medical Center

Samir Narayan
Ph: 734-712-4673

Samir Narayan
Principal Investigator

McLaren Cancer Institute-Flint

Jordan M. Maier
Ph: 313-576-9363

Jordan M. Maier
Principal Investigator

Grand Rapids

Spectrum Health at Butterworth Campus

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Lansing

Sparrow Hospital

Samir Narayan
Ph: 734-712-4673

Samir Narayan
Principal Investigator

Lapeer

McLaren Cancer Institute-Lapeer Region

Jordan M. Maier
Ph: 313-576-9363

Jordan M. Maier
Principal Investigator

Mount Clemens

McLaren Cancer Institute-Macomb

Jordan M. Maier
Ph: 313-576-9363

Jordan M. Maier
Principal Investigator

Mount Pleasant

McLaren Cancer Institute-Central Michigan

Jordan M. Maier
Ph: 313-576-9363

Jordan M. Maier
Principal Investigator

Muskegon

Mercy Health Mercy Campus

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Novi

Assarian Cancer Center

Cynthia Mahesh Vakhariya
Ph: 248-849-5337
Email: jaswinder.grewal@stjohn.org

Cynthia Mahesh Vakhariya
Principal Investigator

Owosso

McLaren Cancer Institute-Owosso

Jordan M. Maier
Ph: 313-576-9363

Jordan M. Maier
Principal Investigator

Petoskey

McLaren Cancer Institute-Northern Michigan

Jordan M. Maier
Ph: 313-576-9363

Jordan M. Maier
Principal Investigator

Pontiac

Saint Joseph Mercy Oakland

Samir Narayan
Ph: 734-712-4673

Samir Narayan
Principal Investigator

Royal Oak

William Beaumont Hospital-Royal Oak

Nayana S. Dekhne
Ph: 248-551-7695

Nayana S. Dekhne
Principal Investigator

Southfield

Providence Hospital-Southfield Cancer Center

Cynthia Mahesh Vakhariya
Ph: 248-849-5337
Email: jaswinder.grewal@stjohn.org

Cynthia Mahesh Vakhariya
Principal Investigator

Troy

21st Century Oncology-Troy

Frank A. Vicini
Ph: 888-326-9729

Frank A. Vicini
Principal Investigator

William Beaumont Hospital - Troy

Nayana S. Dekhne
Ph: 248-551-7695

Nayana S. Dekhne
Principal Investigator

Warren

Saint John Macomb-Oakland Hospital

Samir Narayan
Ph: 734-712-4673

Samir Narayan
Principal Investigator

West Bloomfield

Henry Ford West Bloomfield Hospital

Thomas J. Doyle
Ph: 313-916-1784

Thomas J. Doyle
Principal Investigator

Wyoming

Metro Health Hospital

Kathleen J. Yost
Ph: 616-391-1230
Email: crcwm-regulatory@crcwm.org

Kathleen J. Yost
Principal Investigator

Minnesota
Albert Lea

Mayo Clinic Health System in Albert Lea

Robert W. Mutter
Ph: 855-776-0015

Robert W. Mutter
Principal Investigator

Burnsville

Fairview Ridges Hospital

Richard T. Zera
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

Richard T. Zera
Principal Investigator

Fridley

Unity Hospital

Richard T. Zera
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

Richard T. Zera
Principal Investigator

Mankato

Mayo Clinic Health Systems-Mankato

Robert W. Mutter
Ph: 855-776-0015

Robert W. Mutter
Principal Investigator

Minneapolis

Abbott-Northwestern Hospital

Richard T. Zera
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

Richard T. Zera
Principal Investigator

Northfield

Mayo Clinic Radiation Therapy-Northfield

Robert W. Mutter
Ph: 855-776-0015

Robert W. Mutter
Principal Investigator

Rochester

Mayo Clinic

Robert W. Mutter
Ph: 855-776-0015

Robert W. Mutter
Principal Investigator

Saint Cloud

Coborn Cancer Center at Saint Cloud Hospital

Donald James Jurgens
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Donald James Jurgens
Principal Investigator

Saint Louis Park

Park Nicollet Clinic - Saint Louis Park

Richard T. Zera
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

Richard T. Zera
Principal Investigator

Saint Paul

Regions Hospital

Richard T. Zera
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

Richard T. Zera
Principal Investigator

United Hospital

Richard T. Zera
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

Richard T. Zera
Principal Investigator

Waconia

Ridgeview Medical Center

Richard T. Zera
Ph: 952-993-1517
Email: mmcorc@healthpartners.com

Richard T. Zera
Principal Investigator

Mississippi
Jackson

University of Mississippi Medical Center

Srinivasan Vijayakumar
Ph: 601-815-6700

Srinivasan Vijayakumar
Principal Investigator

Southhaven

Baptist Memorial Hospital-Desoto

Lindi H. VanderWalde
Ph: 901-226-3077

Lindi H. VanderWalde
Principal Investigator

Missouri
Cape Girardeau

Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Chesterfield

Saint Luke's Hospital

Donald F. Busiek
Ph: 314-205-6936

Donald F. Busiek
Principal Investigator

Columbia

University of Missouri - Ellis Fischel

Gregory B. Biedermann
Ph: 573-882-7440

Gregory B. Biedermann
Principal Investigator

Creve Coeur

Barnes-Jewish West County Hospital

Maria Anne Thomas
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Maria Anne Thomas
Principal Investigator

Kansas City

Research Medical Center

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Rakesh Gaur
Principal Investigator

Saint Luke's Hospital of Kansas City

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Rakesh Gaur
Principal Investigator

The University of Kansas Cancer Center-North

Melissa Pulfer Mitchell
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Melissa Pulfer Mitchell
Principal Investigator

The University of Kansas Cancer Center-South

Melissa Pulfer Mitchell
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Melissa Pulfer Mitchell
Principal Investigator

Lee's Summit

Saint Luke's East - Lee's Summit

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Rakesh Gaur
Principal Investigator

The University of Kansas Cancer Center-Lee's Summit

Melissa Pulfer Mitchell
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Melissa Pulfer Mitchell
Principal Investigator

Saint Louis

Missouri Baptist Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Saint Anthony's Medical Center

Minxiang (Michael) Gu
Ph: 888-823-5923
Email: ctsucontact@westat.com

Minxiang (Michael) Gu
Principal Investigator

Washington University School of Medicine

Maria Anne Thomas
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Maria Anne Thomas
Principal Investigator

Saint Peters

Siteman Cancer Center - Saint Peters

Maria Anne Thomas
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Maria Anne Thomas
Principal Investigator

Montana
Billings

Billings Clinic Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Great Falls

Benefis Healthcare- Sletten Cancer Institute

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Kalispell

Kalispell Regional Medical Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Nebraska
Grand Island

CHI Health Saint Francis

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Omaha

Alegent Health Bergan Mercy Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Alegent Health Lakeside Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

University of Nebraska Medical Center

Andrew Owen Wahl
Ph: 402-559-6941
Email: unmcrsa@unmc.edu

Andrew Owen Wahl
Principal Investigator

Nevada
Las Vegas

Radiation Oncology Centers of Nevada Central

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Reno

Renown Regional Medical Center

Michael Chandler Hardacre
Ph: 775-982-4400

Michael Chandler Hardacre
Principal Investigator

New Hampshire
Concord

Concord Hospital

Su Kyong Metcalfe
Ph: 800-441-1138

Su Kyong Metcalfe
Principal Investigator

Lebanon

Dartmouth Hitchcock Medical Center

Alan Charles Hartford
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Alan Charles Hartford
Principal Investigator

Manchester

Elliot Hospital

Brian Robert Knab
Ph: 603-663-1800

Brian Robert Knab
Principal Investigator

New Jersey
Basking Ridge

Memorial Sloan Kettering Cancer Center at Basking Ridge

Beryl McCormick
Ph: 212-639-7202

Beryl McCormick
Principal Investigator

Brick

Ocean Medical Center

Douglas A. Miller
Ph: 732-206-8384

Douglas A. Miller
Principal Investigator

Camden

Cooper Hospital University Medical Center

Ashish Bharat Patel
Ph: 856-325-6757

Ashish Bharat Patel
Principal Investigator

Englewood

Englewood Hospital and Medical Center

David Maximilian Dubin
Ph: 201-894-3456

David Maximilian Dubin
Principal Investigator

Livingston

Saint Barnabas Medical Center

Alison Grann
Ph: 973-322-2470

Alison Grann
Principal Investigator

Middletown

Memorial Sloan Kettering Monmouth Monmouth

Beryl McCormick
Ph: 212-639-7202

Beryl McCormick
Principal Investigator

Mount Holly

Virtua Memorial

Lemuel S. Ariaratnam
Ph: 609-914-6762

Lemuel S. Ariaratnam
Principal Investigator

Neptune

Jersey Shore Medical Center

Douglas A. Miller
Ph: 732-206-8384

Douglas A. Miller
Principal Investigator

New Brunswick

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital

Bruce George Haffty
Ph: 732-235-8675

Bruce George Haffty
Principal Investigator

Paramus

The Valley Hospital-Luckow Pavilion

Laura A. Klein
Ph: 201-634-5792

Laura A. Klein
Principal Investigator

Pennington

Capital Health Medical Center-Hopewell

Shirnett Karean Williamson
Ph: 800-255-3440

Shirnett Karean Williamson
Principal Investigator

Red Bank

Riverview Medical Center/Booker Cancer Center

Douglas A. Miller
Ph: 732-206-8384

Douglas A. Miller
Principal Investigator

Ridgewood

Valley Hospital

Laura A. Klein
Ph: 201-634-5792

Laura A. Klein
Principal Investigator

Somerville

Robert Wood Johnson University Hospital Somerset

Joel K. Braver
Ph: 908-685-2481

Joel K. Braver
Principal Investigator

Sparta

Sparta Cancer Treatment Center

Pramila Rani Anne
Ph: 215-955-6084

Pramila Rani Anne
Principal Investigator

Voorhees

MD Anderson Cancer Center at Cooper-Voorhees

Ashish Bharat Patel
Ph: 856-325-6757

Ashish Bharat Patel
Principal Investigator

Virtua Voorhees

Lemuel S. Ariaratnam
Ph: 609-914-6762

Lemuel S. Ariaratnam
Principal Investigator

Westwood

Valley Health System-Hematology/Oncology

Laura A. Klein
Ph: 201-634-5792

Laura A. Klein
Principal Investigator

New Mexico
Albuquerque

Lovelace Radiation Oncology

Benny J. Liem
Ph: 505-925-0366
Email: LByatt@nmcca.org

Benny J. Liem
Principal Investigator

New Mexico Oncology Hematology Consultants

Benny J. Liem
Ph: 505-925-0366
Email: LByatt@nmcca.org

Benny J. Liem
Principal Investigator

University of New Mexico Cancer Center

Benny J. Liem
Ph: 505-925-0366
Email: LByatt@nmcca.org

Benny J. Liem
Principal Investigator

Las Cruces

Memorial Medical Center - Las Cruces

Benny J. Liem
Ph: 505-925-0366
Email: LByatt@nmcca.org

Benny J. Liem
Principal Investigator

Santa Fe

Christus Saint Vincent Regional Cancer Center

Benny J. Liem
Ph: 505-925-0366
Email: LByatt@nmcca.org

Benny J. Liem
Principal Investigator

New York
Bronx

Montefiore Medical Center - Moses Campus

Jana Lauren Fox
Ph: 718-904-2730
Email: aecc@aecom.yu.edu

Jana Lauren Fox
Principal Investigator

Brooklyn

Maimonides Medical Center

David Michael Berlach
Ph: 718-765-2500

David Michael Berlach
Principal Investigator

New York-Presbyterian/Brooklyn Methodist Hospital

Sameer Rafla-Demetrious
Ph: 718-780-3677
Email: Adg9003@nyp.org

Sameer Rafla-Demetrious
Principal Investigator

Carmel

Putnam Hospital Center

Gregory John Zanieski
Ph: 845-483-6483

Gregory John Zanieski
Principal Investigator

Commack

Memorial Sloan Kettering Commack

Beryl McCormick
Ph: 212-639-7202

Beryl McCormick
Principal Investigator

Cooperstown

Mary Imogene Bassett Hospital

Joy E. Anderson
Ph: 607-547-3073
Email: diana.crean@bassett.org

Joy E. Anderson
Principal Investigator

Fishkill

Vassar Brothers Fishkill Radiation Oncology Center

Gregory John Zanieski
Ph: 845-483-6483

Gregory John Zanieski
Principal Investigator

Kingston

Ulster Radiation Oncology Center

Gregory John Zanieski
Ph: 845-483-6483

Gregory John Zanieski
Principal Investigator

New York

Columbia University/Herbert Irving Cancer Center

Eileen Patricia Connolly
Ph: 212-305-8615

Eileen Patricia Connolly
Principal Investigator

Memorial Sloan-Kettering Cancer Center

Beryl McCormick
Ph: 212-639-7202

Beryl McCormick
Principal Investigator

Poughkeepsie

Vassar Brothers Medical Center

Gregory John Zanieski
Ph: 845-483-6483

Gregory John Zanieski
Principal Investigator

Rochester

Pluta Cancer Center

Yuhchyau Chen
Ph: 585-275-5830

Yuhchyau Chen
Principal Investigator

Rochester General Hospital

Sheema Chawla
Ph: 585-922-3536
Email: tia.derosa@rochestergeneral.org

Sheema Chawla
Principal Investigator

Rockville Centre

Memorial Sloan Kettering Rockville Centre

Beryl McCormick
Ph: 212-639-7202

Beryl McCormick
Principal Investigator

Syracuse

State University of New York Upstate Medical University

Anna Shapiro
Ph: 315-464-5476

Anna Shapiro
Principal Investigator

West Harrison

Memorial Sloan Kettering Westchester

Beryl McCormick
Ph: 212-639-7202

Beryl McCormick
Principal Investigator

North Carolina
Charlotte

Carolinas Medical Center/Levine Cancer Institute

Hadley J. Sharp
Ph: 800-804-9376

Hadley J. Sharp
Principal Investigator

Carolinas Medical Center/Levine Cancer Institute-Pineville

Hadley J. Sharp
Ph: 704-355-2884

Hadley J. Sharp
Principal Investigator

Carolinas Medical Center/Levine Cancer Institute-University

Hadley J. Sharp
Ph: 704-355-2884

Hadley J. Sharp
Principal Investigator

Novant Health Presbyterian Medical Center

Nasfat Shehadeh
Ph: 704-384-5369

Nasfat Shehadeh
Principal Investigator

Concord

Carolinas HealthCare System NorthEast

Hadley J. Sharp
Ph: 800-804-9376

Hadley J. Sharp
Principal Investigator

Durham

Duke University Medical Center

Rachel C. Blitzblau
Ph: 888-275-3853

Rachel C. Blitzblau
Principal Investigator

Gastonia

CaroMont Regional Medical Center

Charles J. Meakin
Ph: 704-834-2932

Charles J. Meakin
Principal Investigator

Greensboro

Cone Health Cancer Center

Vinay K. Gudena
Ph: 336-832-0821

Vinay K. Gudena
Principal Investigator

Greenville

East Carolina University

Eleanor E.R. Harris
Ph: 252-744-2391

Eleanor E.R. Harris
Principal Investigator

Matthews

Matthews Radiation Oncology Center

Nasfat Shehadeh
Ph: 704-384-5369

Nasfat Shehadeh
Principal Investigator

Monroe

Carolinas HealthCare System Union

Hadley J. Sharp
Ph: 800-804-9376

Hadley J. Sharp
Principal Investigator

Supply

South Atlantic Radiation Oncology

Michael A. Papagikos
Ph: 910-251-1839

Michael A. Papagikos
Principal Investigator

Wilmington

Coastal Carolina Radiation Oncology

Michael A. Papagikos
Ph: 910-251-1839

Michael A. Papagikos
Principal Investigator

Ohio
Akron

Akron General Medical Center

Andrew H. Fenton
Ph: 330-344-6348

Andrew H. Fenton
Principal Investigator

Summa Akron City Hospital/Cooper Cancer Center

Desiree E. Doncals
Ph: 330-375-6101

Desiree E. Doncals
Principal Investigator

Barberton

Summa Barberton Hospital

Desiree E. Doncals
Ph: 330-375-6101

Desiree E. Doncals
Principal Investigator

Beachwood

UHHS-Chagrin Highlands Medical Center

Robert R. Shenk
Ph: 800-641-2422

Robert R. Shenk
Principal Investigator

Canton

Aultman Health Foundation

Shruti Trehan
Ph: 330-363-6891

Shruti Trehan
Principal Investigator

Chardon

Geaugra Hospital

Robert R. Shenk
Ph: 800-641-2422

Robert R. Shenk
Principal Investigator

Cincinnati

Bethesda North Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Good Samaritan Hospital - Cincinnati

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

University of Cincinnati/Barrett Cancer Center

Kevin Patrick Redmond
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Kevin Patrick Redmond
Principal Investigator

Cleveland

Case Western Reserve University

Robert R. Shenk
Ph: 800-641-2422

Robert R. Shenk
Principal Investigator

Cleveland Clinic Cancer Center/Fairview Hospital

Rahul Dilip Tendulkar
Ph: 866-223-8100

Rahul Dilip Tendulkar
Principal Investigator

Cleveland Clinic Foundation

Rahul Dilip Tendulkar
Ph: 866-223-8100

Rahul Dilip Tendulkar
Principal Investigator

Columbus

Mount Carmel Health Center West

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Ohio State University Comprehensive Cancer Center

Julia R. White
Ph: 800-293-5066
Email: Jamesline@osumc.edu

Julia R. White
Principal Investigator

The Mark H Zangmeister Center

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Delaware

Delaware Radiation Oncology

Timothy David Moore
Ph: 614-488-2745
Email: sheree@columbusccop.org

Timothy David Moore
Principal Investigator

Independence

Cleveland Clinic Cancer Center Independence

Rahul Dilip Tendulkar
Ph: 866-223-8100

Rahul Dilip Tendulkar
Principal Investigator

Mayfield Heights

Hillcrest Hospital Cancer Center

Rahul Dilip Tendulkar
Ph: 866-223-8100

Rahul Dilip Tendulkar
Principal Investigator

Medina

Summa Health Center at Lake Medina

Desiree E. Doncals
Ph: 330-375-6101

Desiree E. Doncals
Principal Investigator

Mentor

Lake University Ireland Cancer Center

Robert R. Shenk
Ph: 800-641-2422

Robert R. Shenk
Principal Investigator

Middleburg Heights

Southwest General Health Center Ireland Cancer Center

Robert R. Shenk
Ph: 800-641-2422

Robert R. Shenk
Principal Investigator

Parma

University Hospitals Parma Medical Center

Robert R. Shenk
Ph: 800-641-2422

Robert R. Shenk
Principal Investigator

Sandusky

North Coast Cancer Care

Rahul Dilip Tendulkar
Ph: 866-223-8100

Rahul Dilip Tendulkar
Principal Investigator

Strongsville

Cleveland Clinic Cancer Center Strongsville

Rahul Dilip Tendulkar
Ph: 866-223-8100

Rahul Dilip Tendulkar
Principal Investigator

West Chester

University Pointe

Kevin Patrick Redmond
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Kevin Patrick Redmond
Principal Investigator

Westlake

UHHS-Westlake Medical Center

Robert R. Shenk
Ph: 800-641-2422

Robert R. Shenk
Principal Investigator

Wooster

Cleveland Clinic Wooster Family Health and Surgery Center

Rahul Dilip Tendulkar
Ph: 866-223-8100

Rahul Dilip Tendulkar
Principal Investigator

Oklahoma
Lawton

Cancer Centers of Southwest Oklahoma Research

Terence S. Herman
Ph: 405-271-8777
Email: ou-clinical-trials@ouhsc.edu

Terence S. Herman
Principal Investigator

Oklahoma City

Mercy Hospital Oklahoma City

Terence S. Herman
Ph: 405-271-8777
Email: ou-clinical-trials@ouhsc.edu

Terence S. Herman
Principal Investigator

University of Oklahoma Health Sciences Center

Terence S. Herman
Ph: 405-271-8777
Email: ou-clinical-trials@ouhsc.edu

Terence S. Herman
Principal Investigator

Oregon
Eugene

Willamette Valley Cancer Center

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Portland

Compass Oncology Rose Quarter

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Kaiser Permanente Northwest

Sandeep Hashmukh Mashru
Ph: 503-335-2400

Sandeep Hashmukh Mashru
Principal Investigator

The Dalles

Mid-Columbia Medical Center/Celilo Cancer Center

Keith J. Stelzer
Ph: 541-296-7585

Keith J. Stelzer
Principal Investigator

Pennsylvania
Allentown

Lehigh Valley Hospital-Cedar Crest

Samir Narayan
Ph: 734-712-4673

Samir Narayan
Principal Investigator

Beaver

UPMC-Heritage Valley Health System Beaver

Sushil Beriwal
Ph: 412-647-2811

Sushil Beriwal
Principal Investigator

Bethlehem

Saint Luke's University Hospital-Bethlehem Campus

Nimisha Deb
Ph: 610-954-3582
Email: infolink@slhn.org

Nimisha Deb
Principal Investigator

Chadds Ford

Christiana Care Health System-Concord Health Center

Gregory Andrew Masters
Ph: 302-733-6227

Gregory Andrew Masters
Principal Investigator

Dunmore

Northeast Radiation Oncology Center

Pramila Rani Anne
Ph: 215-955-6084

Pramila Rani Anne
Principal Investigator

Ephrata

Ephrata Cancer Center

L. Eamonn Boyle
Ph: 877-441-7957

L. Eamonn Boyle
Principal Investigator

Erie

The Regional Cancer Center

Andrew Thomas Figura
Ph: 814-838-0448
Email: mhaynes@trcc.org

Andrew Thomas Figura
Principal Investigator

Furlong

Fox Chase Cancer Center Buckingham

Bizhan Micaily
Ph: 215-728-2983

Bizhan Micaily
Principal Investigator

Gettysburg

Adams Cancer Center

L. Eamonn Boyle
Ph: 877-441-7957

L. Eamonn Boyle
Principal Investigator

Greensburg

UPMC Cancer Centers - Arnold Palmer Pavilion

Sushil Beriwal
Ph: 412-647-2811

Sushil Beriwal
Principal Investigator

Harrisburg

PinnacleHealth Cancer Center-Community Campus

Joella E. Wilson-Dagar
Ph: 717-724-6765
Email: klitchfield@PINNACLEHEALTH.org

Joella E. Wilson-Dagar
Principal Investigator

Hershey

Penn State Milton S Hershey Medical Center

Jennifer C. Rosenberg
Ph: 717-531-3779
Email: CTO@hmc.psu.edu

Jennifer C. Rosenberg
Principal Investigator

Meadowbrook

Holy Redeemer Hospital and Medical Center

Sheena K. Jain
Ph: 215-938-3551

Sheena K. Jain
Principal Investigator

Monroeville

Intercommunity Cancer Center

Thomas Benjamin Julian
Ph: 877-284-2000

Thomas Benjamin Julian
Principal Investigator

Moon Township

UPMC-Coraopolis/Heritage Valley Radiation Oncology

Sushil Beriwal
Ph: 412-647-2811

Sushil Beriwal
Principal Investigator

Natrona Heights

Allegheny Valley Hospital

Thomas Benjamin Julian
Ph: 877-284-2000

Thomas Benjamin Julian
Principal Investigator

Philadelphia

Fox Chase Cancer Center

Bizhan Micaily
Ph: 215-728-2983

Bizhan Micaily
Principal Investigator

Pennsylvania Hospital

Gary Mitchel Freedman
Ph: 215-728-4790

Gary Mitchel Freedman
Principal Investigator

Thomas Jefferson University Hospital

Pramila Rani Anne
Ph: 215-955-6084

Pramila Rani Anne
Principal Investigator

University of Pennsylvania/Abramson Cancer Center

Gary Mitchel Freedman
Ph: 215-728-4790

Gary Mitchel Freedman
Principal Investigator

Pittsburgh

Allegheny General Hospital

Thomas Benjamin Julian
Ph: 877-284-2000

Thomas Benjamin Julian
Principal Investigator

UPMC-Magee Womens Hospital

Sushil Beriwal
Ph: 412-647-2811

Sushil Beriwal
Principal Investigator

UPMC-Saint Margaret

Sushil Beriwal
Ph: 412-647-2811

Sushil Beriwal
Principal Investigator

UPMC-Shadyside Hospital

Sushil Beriwal
Ph: 412-647-2811

Sushil Beriwal
Principal Investigator

West Reading

Reading Hospital

Terrence Paul Cescon
Ph: 610-988-9323

Terrence Paul Cescon
Principal Investigator

Wexford

Wexford Health and Wellness Pavilion

Thomas Benjamin Julian
Ph: 877-284-2000

Thomas Benjamin Julian
Principal Investigator

York

WellSpan Health-York Hospital

L. Eamonn Boyle
Ph: 877-441-7957

L. Eamonn Boyle
Principal Investigator

Rhode Island
Providence

Radiation Oncology Associates Incorporated

Kara Lynne Leonard
Ph: 401-444-1488

Kara Lynne Leonard
Principal Investigator

Rhode Island Hospital

Kara Lynne Leonard
Ph: 401-444-1488

Kara Lynne Leonard
Principal Investigator

Women and Infants Hospital

William Marshall Sikov
Ph: 401-274-1122

William Marshall Sikov
Principal Investigator

Warwick

Kent County Hospital

Naveed Asalm Rana
Ph: 401-737-7010

Naveed Asalm Rana
Principal Investigator

South Carolina
Charleston

Bon Secours Saint Francis Hospital

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Medical University of South Carolina

Jennifer L. Harper
Ph: 843-792-9321

Jennifer L. Harper
Principal Investigator

Roper Hospital

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Georgetown

Georgetown Hospital System

Jennifer L. Harper
Ph: 843-792-9321

Jennifer L. Harper
Principal Investigator

Greenville

Greenville Health System Cancer Institute-Eastside

David Lawrence Grisell
Ph: 864-241-6251

David Lawrence Grisell
Principal Investigator

Greenville Health System Cancer Institute-Faris

David Lawrence Grisell
Ph: 864-241-6251

David Lawrence Grisell
Principal Investigator

Saint Francis Cancer Center

Robert D. Siegel
Ph: 864-255-1713

Robert D. Siegel
Principal Investigator

Greer

Gibbs Cancer Center-Pelham

Steven William Corso
Ph: 800-486-5941

Steven William Corso
Principal Investigator

Greenville Health System Cancer Institute-Greer

David Lawrence Grisell
Ph: 864-241-6251

David Lawrence Grisell
Principal Investigator

Hilton Head Island

The Radiation Oncology Center-Hilton Head/Bluffton

John A. Pablo
Ph: 912-819-5704

John A. Pablo
Principal Investigator

Seneca

Greenville Health System Cancer Institute-Seneca

David Lawrence Grisell
Ph: 864-241-6251

David Lawrence Grisell
Principal Investigator

Spartanburg

Greenville Health System Cancer Institute-Spartanburg

David Lawrence Grisell
Ph: 864-241-6251

David Lawrence Grisell
Principal Investigator

Spartanburg Medical Center

Steven William Corso
Ph: 800-486-5941

Steven William Corso
Principal Investigator

West Columbia

Lexington Medical Center

Steven A. Madden
Ph: 803-936-8050

Steven A. Madden
Principal Investigator

Tennessee
Germantown

The West Clinic - Wolf River

Noam A. VanderWalde
Ph: 901-516-2579

Noam A. VanderWalde
Principal Investigator

Knoxville

Thompson Cancer Survival Center

Grant Michael Clark
Ph: 865-331-1812

Grant Michael Clark
Principal Investigator

Memphis

Baptist Memorial Hospital and Cancer Center-Memphis

Lindi H. VanderWalde
Ph: 901-226-3077

Lindi H. VanderWalde
Principal Investigator

Nashville

Vanderbilt University/Ingram Cancer Center

Anuradha Bapsi Chakravarthy
Ph: 800-811-8480

Anuradha Bapsi Chakravarthy
Principal Investigator

Texas
Abilene

Texas Cancer Center

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Amarillo

The Don and Sybil Harrington Cancer Center

Daniel Arsenault
Ph: 806-212-1985
Email: gcravey@harringtoncc.org

Daniel Arsenault
Principal Investigator

Arlington

Texas Oncology-Arlington South

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Austin

Texas Oncology - Central Austin Cancer Center

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Texas Oncology - South Austin Cancer Center

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Texas Oncology-Austin Midtown

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Bedford

Texas Oncology Bedford

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Dallas

Parkland Memorial Hospital

Ann Marilyn Leitch
Ph: 214-648-7097

Ann Marilyn Leitch
Principal Investigator

UT Southwestern/Simmons Cancer Center-Dallas

Ann Marilyn Leitch
Ph: 214-648-7097

Ann Marilyn Leitch
Principal Investigator

Flower Mound

Texas Oncology-Flower Mound

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Houston

M D Anderson Cancer Center

Simona F. Shaitelman
Ph: 713-792-3245

Simona F. Shaitelman
Principal Investigator

MD Anderson Regional Care Center-Katy

Simona F. Shaitelman
Ph: 713-792-3245

Simona F. Shaitelman
Principal Investigator

Memorial Hermann Memorial City Medical Center

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

The Methodist Hospital System

Angel Augusto Rodriguez
Ph: 713-790-2700

Angel Augusto Rodriguez
Principal Investigator

Laredo

Doctor's Hospital of Laredo

Gary Walter Unzeitig
Ph: 888-823-5923
Email: ctsucontact@westat.com

Gary Walter Unzeitig
Principal Investigator

Lubbock

Covenant Medical Center-Lakeside

Ibrahim Adly Shalaby
Ph: 806-725-8000
Email: jaccresearch@covhs.org

Ibrahim Adly Shalaby
Principal Investigator

University Medical Center

Rakhshanda Layeequr Rahman
Ph: 806-354-5411

Rakhshanda Layeequr Rahman
Principal Investigator

Nassau Bay

MD Anderson Regional Care Center-Bay Area

Simona F. Shaitelman
Ph: 713-792-3245

Simona F. Shaitelman
Principal Investigator

Plano

Texas Oncology-Plano West

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Round Rock

Scott and White Healthcare Round Rock

Lucas Wong
Ph: 254-724-5407

Lucas Wong
Principal Investigator

Texas Oncology - Round Rock Cancer Center

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

San Antonio

University of Texas Health Science Center at San Antonio

Richard L. Crownover
Ph: 210-450-3800
Email: CTO@uthscsa.edu

Richard L. Crownover
Principal Investigator

Sherman

Texas Cancer Center-Sherman

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Sugar Land

Houston Methodist Sugar Land Hospital

Angel Augusto Rodriguez
Ph: 713-790-2700

Angel Augusto Rodriguez
Principal Investigator

MD Anderson Regional Care Center-Sugar Land

Simona F. Shaitelman
Ph: 713-792-3245

Simona F. Shaitelman
Principal Investigator

Texas Oncology Cancer Center Sugar Land

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Temple

Scott and White Memorial Hospital

Lucas Wong
Ph: 254-724-5407

Lucas Wong
Principal Investigator

The Woodlands

MD Anderson Regional Care Center-The Woodlands

Simona F. Shaitelman
Ph: 713-792-3245

Simona F. Shaitelman
Principal Investigator

Webster

Deke Slayton Cancer Center

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Utah
Murray

Intermountain Medical Center

Vilija N. Avizonis
Ph: 801-507-3950

Vilija N. Avizonis
Principal Investigator

Ogden

McKay-Dee Hospital Center

Vilija N. Avizonis
Ph: 801-507-3950

Vilija N. Avizonis
Principal Investigator

Provo

Utah Valley Regional Medical Center

Vilija N. Avizonis
Ph: 801-507-3950

Vilija N. Avizonis
Principal Investigator

Salt Lake City

Huntsman Cancer Institute/University of Utah

Matthew M. Poppe
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

Matthew M. Poppe
Principal Investigator

South Jordan

South Jordan Health Center

Matthew M. Poppe
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

Matthew M. Poppe
Principal Investigator

Vermont
Saint Johnsbury

Norris Cotton Cancer Center-North

Alan Charles Hartford
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Alan Charles Hartford
Principal Investigator

Virginia
Alexandria

Inova Alexandria Hospital

Jane Grayson
Ph: 703-776-2580
Email: Stephanie.VanBebber@inova.org

Jane Grayson
Principal Investigator

Charlottesville

University of Virginia Cancer Center

Shayna Lefrak Showalter
Ph: 434-243-6322
Email: JME3D@hscmail.mcc.virginia.edu

Shayna Lefrak Showalter
Principal Investigator

Falls Church

Inova Fairfax Hospital

Ashish K. Chawla
Ph: 703-208-6650
Email: Stephanie.VanBebber@inova.org

Ashish K. Chawla
Principal Investigator

Fishersville

Augusta Health Cancer Center

Robert M. Kyler
Ph: 540-245-7106

Robert M. Kyler
Principal Investigator

Fredericksburg

Mary Washington Hospital

Harry Douglas Bear
Ph: 804-628-1939

Harry Douglas Bear
Principal Investigator

Hampton

Sentara Cancer Institute at Sentara CarePlex Hospital

Mark E. Shaves
Ph: 757-388-2406

Mark E. Shaves
Principal Investigator

Norfolk

Sentara Norfolk General Hospital

Mark E. Shaves
Ph: 757-388-2406

Mark E. Shaves
Principal Investigator

Portsmouth

Naval Medical Center - Portsmouth

Andrew S. Camarata
Ph: 757-953-5939

Andrew S. Camarata
Principal Investigator

Richmond

Virginia Commonwealth University/Massey Cancer Center

Harry Douglas Bear
Ph: 804-628-1939

Harry Douglas Bear
Principal Investigator

Roanoke

Oncology and Hematology Associates of Southwest Virginia

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

Virginia Beach

Sentara Virginia Beach General Hospital

Mark E. Shaves
Ph: 757-388-2406

Mark E. Shaves
Principal Investigator

Washington
Auburn

MultiCare Auburn Medical Center

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Bellevue

Overlake Hospital Medical Center

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Bremerton

Harrison Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Federal Way

Virginia Mason Federal Way Medical Center

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Gig Harbor

MultiCare Gig Harbor Medical Park

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Gig Harbor

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Kennewick

Tri-Cities Cancer Center

Janice Nam Kim
Ph: 800-804-8824

Janice Nam Kim
Principal Investigator

Lacey

Providence Regional Cancer System-Lacey

Benjamin Buckner Bridges
Ph: 208-381-3376
Email: mcdonagd@slhs.org

Benjamin Buckner Bridges
Principal Investigator

Mount Vernon

Skagit Valley Hospital Regional Cancer Care Center

Janice Nam Kim
Ph: 800-804-8824

Janice Nam Kim
Principal Investigator

Puyallup

MultiCare Good Samaritan Hospital

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Puyallup

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Seattle

Fred Hutchinson Cancer Research Center

Janice Nam Kim
Ph: 800-804-8824

Janice Nam Kim
Principal Investigator

Seattle Cancer Care Alliance

Janice Nam Kim
Ph: 800-804-8824

Janice Nam Kim
Principal Investigator

University of Washington Medical Center

Janice Nam Kim
Ph: 800-804-8824

Janice Nam Kim
Principal Investigator

Virginia Mason Medical Center

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Spokane

Cancer Care Northwest - Spokane South

Janice Nam Kim
Ph: 800-804-8824

Janice Nam Kim
Principal Investigator

Cancer Care Northwest-North Spokane

Janice Nam Kim
Ph: 800-804-8824

Janice Nam Kim
Principal Investigator

Spokane Valley Cancer Center-Mayfair

Janice Nam Kim
Ph: 800-804-8824

Janice Nam Kim
Principal Investigator

Tacoma

MultiCare Tacoma General Hospital

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Northwest Medical Specialties PLLC

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Saint Joe's

John A. Keech
Ph: 253-403-2394

John A. Keech
Principal Investigator

Vancouver

Compass Oncology Vancouver

Vivek S. Kavadi
Ph: 281-277-5200

Vivek S. Kavadi
Principal Investigator

West Virginia
Morgantown

West Virginia University Healthcare

Hannah Wright Hazard
Ph: 304-293-7374
Email: cancertrialsinfo@hsc.wvu.edu

Hannah Wright Hazard
Principal Investigator

Wisconsin
Antigo

Langlade Hospital and Cancer Center

Harish G. Ahuja
Ph: 877-405-6866

Harish G. Ahuja
Principal Investigator

Appleton

Fox Valley Surgical Associates Limited

Editha (Edie) A. Krueger
Ph: 920-380-1500

Editha (Edie) A. Krueger
Principal Investigator

Radiology Associates of Appleton/ThedaCare Regional Medical Center

Editha (Edie) A. Krueger
Ph: 920-380-1500

Editha (Edie) A. Krueger
Principal Investigator

ThedaCare Regional Cancer Center

Editha (Edie) A. Krueger
Ph: 920-380-1500

Editha (Edie) A. Krueger
Principal Investigator

Eau Claire

Sacred Heart Hospital

Jessica A. Wernberg
Ph: 715-389-4457

Jessica A. Wernberg
Principal Investigator

Grafton

Aurora Cancer Care-Grafton

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

Green Bay

Aurora BayCare Medical Center

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

Saint Vincent Hospital Cancer Center at Saint Mary's

Matthew L. Ryan
Ph: 920-433-8889

Matthew L. Ryan
Principal Investigator

Saint Vincent Hospital Cancer Center Green Bay

Matthew L. Ryan
Ph: 920-433-8889

Matthew L. Ryan
Principal Investigator

Johnson Creek

UW Cancer Center Johnson Creek

Bethany Marie Anderson
Ph: 877-405-6866

Bethany Marie Anderson
Principal Investigator

Kenosha

Aurora Cancer Care-Kenosha South

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

La Crosse

Gundersen Lutheran Medical Center

Kurt Oettel
Ph: 608-775-2385
Email: cancerctr@gundersenhealth.org

Kurt Oettel
Principal Investigator

Mayo Clinic Health System-Franciscan Healthcare

Robert W. Mutter
Ph: 855-776-0015

Robert W. Mutter
Principal Investigator

Madison

University of Wisconsin Hospital and Clinics

Bethany Marie Anderson
Ph: 877-405-6866

Bethany Marie Anderson
Principal Investigator

Marshfield

Marshfield Clinic

Jessica A. Wernberg
Ph: 715-389-4457

Jessica A. Wernberg
Principal Investigator

Saint Joseph's Hospital

Jessica A. Wernberg
Ph: 715-389-4457

Jessica A. Wernberg
Principal Investigator

Menomonee Falls

Community Memorial Hospital

Adam D. Currey
Ph: 414-805-4380

Adam D. Currey
Principal Investigator

Milwaukee

Aurora Saint Luke's Medical Center

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

Aurora Sinai Medical Center

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

Froedtert and the Medical College of Wisconsin

Adam D. Currey
Ph: 414-805-4380

Adam D. Currey
Principal Investigator

Minocqua

Marshfield Clinic-Minocqua Center

Jessica A. Wernberg
Ph: 715-389-4457

Jessica A. Wernberg
Principal Investigator

Neenah

Surgical Associates of Neenah SC

Editha (Edie) A. Krueger
Ph: 920-380-1500

Editha (Edie) A. Krueger
Principal Investigator

Oconomowoc

ProHealth Oconomowoc Memorial Hospital

Wingate F. Clapper
Ph: 262-928-7632
Email: Chanda.miller@phci.org

Wingate F. Clapper
Principal Investigator

Oshkosh

Vince Lombardi Cancer Clinic - Oshkosh

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

Racine

Wheaton Franciscan Cancer Care - All Saints

James H. Taylor
Ph: 262-785-2273

James H. Taylor
Principal Investigator

Rice Lake

Marshfield Clinic-Rice Lake Center

Jessica A. Wernberg
Ph: 715-389-4457

Jessica A. Wernberg
Principal Investigator

Stevens Point

Marshfield Clinic Stevens Point Center

Jessica A. Wernberg
Ph: 715-389-4457

Jessica A. Wernberg
Principal Investigator

Summit

Aurora Medical Center in Summit

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

Two Rivers

Vince Lombardi Cancer Clinic-Two Rivers

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

Waukesha

ProHealth Waukesha Memorial Hospital

Wingate F. Clapper
Ph: 262-928-7632
Email: Chanda.miller@phci.org

Wingate F. Clapper
Principal Investigator

UW Cancer Center at ProHealth Care

Wingate F. Clapper
Ph: 262-928-7632
Email: Chanda.miller@phci.org

Wingate F. Clapper
Principal Investigator

Wausau

Aspirus Regional Cancer Center

Harish G. Ahuja
Ph: 877-405-6866

Harish G. Ahuja
Principal Investigator

Wauwatosa

Aurora Cancer Care-Milwaukee West

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

West Allis

Aurora West Allis Medical Center

Ellen L. Ziaja
Ph: 800-252-2990

Ellen L. Ziaja
Principal Investigator

West Bend

The Alyce and Elmore Kraemer Cancer Care Center

Adam D. Currey
Ph: 414-805-4380

Adam D. Currey
Principal Investigator

Weston

Diagnostic and Treatment Center

Jessica A. Wernberg
Ph: 715-389-4457

Jessica A. Wernberg
Principal Investigator

Canada

Alberta
Calgary

Tom Baker Cancer Centre

Keith Tankel
Ph: 780-432-8500

Keith Tankel
Principal Investigator

Edmonton

Cross Cancer Institute

Keith Tankel
Ph: 780-432-8500

Keith Tankel
Principal Investigator

Manitoba
Winnipeg

CancerCare Manitoba

Mohamed Ali M. Akra
Ph: 866-561-1026
Email: CIO_Web@cancercare.mb.ca

Mohamed Ali M. Akra
Principal Investigator

New Brunswick
Saint John

Atlantic Health Sciences Corporation-Saint John Regional Hospital

Farah Naz
Ph: 506-648-6890

Farah Naz
Principal Investigator

Quebec
Montreal

CIUSSSEMTL-Hopital Maisonneuve-Rosemont

Michael Yassa
Ph: 514-252-3400ext3329

Michael Yassa
Principal Investigator

McGill University Department of Oncology

Christine Lambert
Ph: 514-934-4400

Christine Lambert
Principal Investigator

Quebec City

CHU de Quebec-L'Hotel-Dieu de Quebec (HDQ)

Valerie Theberge
Email: rechclinique@crchuq.ulaval.ca

Valerie Theberge
Principal Investigator

Sherbrooke

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont

Valerie Theberge
Email: rechclinique@crchuq.ulaval.ca

Valerie Theberge
Principal Investigator

Saskatchewan
Regina

Allan Blair Cancer Centre

Derek Suderman
Ph: 306-766-2213

Derek Suderman
Principal Investigator

Saskatoon

Saskatoon Cancer Centre

Duc M. Le
Ph: 306-655-2914

Duc M. Le
Principal Investigator

Ireland

Dublin

Saint Lukes Hospital

Orla McArdle
Ph: 353 1 8092063

Orla McArdle
Principal Investigator

Galway

University College Hospital Galway

Joseph Daniel Martin
Ph: 353 1 6677211
Email: info@cancercontrol.ie

Joseph Daniel Martin
Principal Investigator

Japan

Akashi-city

Hyogo Cancer Center

Koji Matsumoto
Ph: 81 78-929-1151

Koji Matsumoto
Principal Investigator

Gunma

Gunma University Hospital

Takashi Nakano
Ph: 81-27-220-7626

Takashi Nakano
Principal Investigator

Morioka

Iwate Medical University School of Medicine

Hideaki Komatsu
Ph: 019-651-5111

Hideaki Komatsu
Principal Investigator

Niigata City

Niigata University Medical and Dental Hospital

Masayuki Nagahashi
Ph: 81-025-223-6161

Masayuki Nagahashi
Principal Investigator

Saitama

Saitama Medical University International Medical Center

Akihiko Osaki
Ph: 81-49-276-2028

Akihiko Osaki
Principal Investigator

Sapporo

Hokkaido University Hospital

Hiroko Yamashita
Email: hassi@med.hokudai.ac.jp

Hiroko Yamashita
Principal Investigator

Tokyo

National Cancer Center Hospital

Jun Itami
Ph: 81-3-3542-2511
Email: www-admin@ncc.go.jp

Jun Itami
Principal Investigator

Republic of Korea

Seoul

Yonsei University Health System-Severance Hospital

Yong Bae Kim
Email: ihcc@yuhs.ac

Yong Bae Kim
Principal Investigator

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT01872975

Note: Information about participating sites on pharmaceutical industry trials may be incomplete. Please visit the ClinicalTrials.gov record via the link above for more information about participating sites.