Melphalan Flufenamide Hydrochloride
This page contains brief information about melphalan flufenamide hydrochloride and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.
FDA label information for this drug is available at DailyMed.
Use in Cancer
Melphalan flufenamide hydrochloride is approved to be used with dexamethasone to treat:
- Multiple myeloma that has relapsed (come back) or is refractory (does not respond to treatment). It is used in adults who have received at least four treatments that included an anti-CD38 monoclonal antibody, a proteasome inhibitor, and an immunomodulating agent.
This use is approved under FDA’s Accelerated Approval Program. As a condition of approval, confirmatory trial(s) must show that melphalan flufenamide hydrochloride provides a clinical benefit in these patients.
Melphalan is also available in other forms. For more information, see the Drug Information Summaries for Melphalan and Melphalan Hydrochloride.
Melphalan flufenamide hydrochloride is also being studied in the treatment of other types of cancer.
More About Melphalan Flufenamide Hydrochloride
Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.
Research Results and Related Resources
Clinical Trials Accepting Patients
Find Clinical Trials for Melphalan Flufenamide Hydrochloride - Check for trials from NCI's list of cancer clinical trials now accepting patients.