Stories of Impact

These stories from NCI's Annual Plan and Budget Proposal for Fiscal Year 2019 highlight how cancer research helps people live healthier lives and describe the work of NCI-funded scientists.

Understanding the Mechanisms of Cancer

Identifying Molecular Changes That Drive Cancer

Thinking Chemically to Discover New Targeted Cancer Drugs

Kevan Shokat, Ph.D.
Chemical biologist Kevan Shokat, Ph.D.
University of California, San Francisco
Howard Hughes Medical Institute

Learning How Cancer Spreads and How to Stop It

Shining a Spotlight on the Exosome

David Lyden, M.D., Ph.D.
Pediatric neuro-oncologist and researcher David Lyden, M.D., Ph.D.
Weill Cornell Medical College
Memorial Sloan Kettering Cancer Center

Preventing Cancer

Developing Vaccines to Prevent Cancers Not Caused by Viruses

Pursuing a Cancer Prevention Vaccine

Olivera Finn, Ph.D.
Cancer vaccine researcher Olivera Finn, Ph.D.
University of Pittsburgh

Detecting and Diagnosing Cancer

Improving Early Detection to Reduce the Burden of Cancer

Brushing the Airway to Detect Lung Cancer Earlier

Avrum Spira, M.D., M.Sc.
Physician, researcher and entrepreneur Avrum Spira, M.D., M.Sc.
Boston University-Boston Medical Center Cancer Center

Treating Cancer

Combining Therapies to Improve Outcomes

Combining Drugs to Treat Ovarian Cancer

Betsy Brauser
Betsy Brauser is an ovarian cancer survivor who lives in Florida
Ovarian Cancer Survivor
Florida

Stopping Multiple Myeloma in Its Tracks

Valerie Winston
Valerie Winston is a smoldering myeloma survivor who lives in Maryland
Smoldering Myeloma Survivor
Maryland

Joining Forces against Cancer

Robert Vonderheide, M.D., D. Phil.
Cancer immunologist and oncologist Robert (Bob) Vonderheide, M.D., D.Phil.
University of Pennsylvania

Developing Precision Immunotherapies

Making the Case for Biomarkers

T.J. Sharpe
T.J. Sharpe is a melanoma survivor from Florida
Melanoma Survivor
Florida

Developing the First Precision Medicine

Prembrolizumab
Treating tumors based on genetic characteristics instead of cancer site of origin

Developing New Treatments for Children with Cancer

Improving Outcomes for Patients with NF1

Philip Moss
Nine-year-old Philip Moss, of Alabama, is a neurofibroma survivor
Neurofibroma Survivor
Alabama

Using Tandem Transplants to Treat Neuroblastoma

Julie Park, M.D.
Pediatric oncologist and researcher Julie Park, M.D.
Seattle Children’s Hospital
University of Washington School of Medicine
Fred Hutchinson Cancer Research Center

Searching for Less-Toxic Treatments

Gregory Aune, M.D., Ph.D.
Childhood cancer survivor, pediatric oncologist and cancer research advocate Gregory Aune, M.D., Ph.D.
University of Texas Health Science Center at San Antonio

Advancing Public Health in Cancer

Understanding the Influence of Body Weight and Physical Activity on Cancer Risk and Outcomes

Running (and Eating) Away from Cancer

Sue Wharfe
Sue Wharfe is a breast cancer survivor from Connecticut
Breast Cancer Survivor
Connecticut

Reducing Tobacco Use Before and After a Cancer Diagnosis

Working to Reduce the Cancer Burden Caused by Tobacco

Michael Fiore, M.D., M.P.H., M.B.A.
Researcher Michael Fiore, M.D., M.P.H., M.B.A., helped spearhead a working group of the NCI Board of Scientific Advisors which is working  to shape future tobacco control research
University of Wisconsin School of Medicine

Delivering High-Quality Cancer Care to All Americans

Addressing Cancer Disparities in Appalachia

Electra Paskett, Ph.D.
Electra Paskett, Ph.D. has devoted her 30-year career to addressing cancer disparities experienced by underserved groups in the United States.
The Ohio State University College of Medicine

Strengthening the Cancer Research Enterprise

Fighting Cancers with a Sea Sponge

Eribulin Mesylate
Turning a natural product into a new drug to treat cancer

Bringing Research to the Community to Reduce Disparities

Chanita Hughes-Halbert, Ph.D.
Chanita Hughes-Halbert, Ph.D., a nationally recognized leader in cancer disparities research and behavioral science at Medical University of South Carolina
Medical University of South Carolina