2015 - CCG Updates & Insights
- The Cancer Genome Atlas: More Than a Large Collection of Data
Though TCGA will wrap up in 2016 with a concluding symposium, cancer genomics projects built upon the success of TCGA will continue to play a major part in the NCI’s mission to better understand and treat cancer in the years to come.
- Cancer Informatics: Expanding Access to Cancer Genomics Data
Drs. Staudt and Kibbe discuss the NCI’s major initiatives to improve both the accessibility and usability of cancer genomics data. Top among the NCI’s priorities are the Genomic Data Commons, a service that will bring together and harmonize cancer genomic data sets from NCI programs and non-NCI data submitters, and the Cancer Genomics Cloud Pilots.
- Researcher Interview: Matthew Meyerson
In this interview, Matthew Meyerson, M.D., Ph.D., Professor of Pathology at Dana-Farber Cancer Institute and Harvard Medical School, talks about the clinical impact of his research on lung cancer and discusses developing technologies and ongoing challenges in the field of cancer genomics.
- Funding Opportunity: Genomic Data Analysis Network Centers
The National Cancer Institute (NCI) has published three companion Funding Opportunity Announcements (FOAs) for Genomic Data Analysis Network Centers to support programs of the Center for Cancer Genomics (CCG). The FOAs are managed by CCG and solicit applications for a Processing Genomic Data Center, a Visualization Genomic Data Center, and a Specialized Genomic Data Center.
- Study Identifies Biomarker that Detects Early Pancreatic Cancer
Researchers from the University of Texas MD Anderson Cancer Center have identified a protein marker that is found at much higher levels in exosomes that derive from cancer cells compared to healthy cells, a discovery that may improve the detection and treatment of pancreatic cancer.
- Divide and Conquer: The Molecular Diagnosis of Cancer
CCG promotes the transformation of cancer diagnosis and treatment through genomics. Using a “team science” approach, CCG supports research in structural, functional, and computational genomics that provide data and resources to the cancer research community.
- American Society of Clinical Oncology (ASCO) Recognizes TCGA’s Importance in the Past Decade and in Tumor Biology
The American Society of Clinical Oncology (ASCO) highlighted TCGA’s role in advancing knowledge about cancer genes, pathways, and subtypes, in its 2015 Annual Report on Progress Against Cancer.
- Researchers use Modified CRISPR Systems to Modulate Gene Expression on a Genomic Scale
Cancer Target Discovery and Development Network (CTD2) researchers at the University of California, San Francisco, developed a CRISPR system that can regulate both gene repression and activation with fewer off-target effects.