An illustration of revumenib's mechanism of action. In the top panel, circles representing the proteins MLL1 and menin are bound together to form a protein complex. That complex, in turn, binds to chromatin and triggers the production of AML cells. In the bottom panel, revumenib blocks MLL1 from binding to menin and forming a protein complex that can bind to chromatin. The cells that had acted like haywire stems cells then either turn back into normal cells through a process called differentiation or die.