2019 Alliance for Nanotechnology in Cancer Principal Investigators’ Meeting

Meeting Information

Location

The 2019 NCI Nano Alliance PI Meeting will be held on the Shady Grove Campus of the National Cancer Institute, Rockville, Maryland from September 24 to 26.

National Cancer Institute, Shady Grove
Conference Rooms 406/408/410
9609 Medical Center Drive
Rockville, MD

Meals

Due to changes in U.S. Department of Health and Human Services policy, meals can no longer be provided at our meetings. Attendees will be responsible for meals and/or light refreshments on their own at their own cost. The Shady Grove Campus has a café and a full-service cafeteria directly across from the conference center.

Registration

Including PI(s), the following slots have been allotted for each award:

7 participation slots for each Center of Cancer Nanotechnology Excellence
3 participation slots for each Innovative Research in Cancer Nanotechnology award
4 participation slots for each T32 Cancer Nanotechnology Training Center

Registration deadline: Wednesday, September 11, 2019

Lodging and Travel

Hotel

The NCI room block is at the Hilton Garden Inn. To reserve your room, go to our reservation page for the Hilton Garden Inn and use the group name in your confirmation email.

Alternative hotels near the Shady Grove Campus:

Hilton Garden Inn Rockville Gaithersburg
14975 Shady Grove Rd, Rockville, MD 20850
(240) 507-1800

Courtyard by Marriott Rockville
2500 Research Blvd, Rockville, MD 20850
(301) 670-6700

Homewood Suites by Hilton Rockville-Gaithersburg
14975 Shady Grove Rd, Rockville, MD 20850
(240) 507-1900

Extended Stay America - Washington D.C. – Rockville
2621 Research Blvd, Rockville, MD 20850
(301) 654-8111

Transportation

Traveling by Metro: The closest Metro (subway) stop to NCI Shady Grove is the Shady Grove Metro Station, on the Red Line. There is a free NCI shuttle from the metro to the NCI campus.

From the Hilton Garden Inn: The hotel shuttle is an 11 person shuttle that will make several trips until all attendees have been transported. Additionally, the Hilton Garden Inn is only a short 12 minute walk from NCI Shady Grove, should you wish to walk.

Traveling by plane: The closest airports to the hotel are Ronald Reagan Washington National Airport (DCA) and Washington Dulles International Airport (IAD); however, Baltimore-Washington International Thurgood Marshall Airport (BWI) also serves the Washington, D.C., area. The Metro system is accessible from Ronald Reagan Washington National Airport. Taxi service is available from all airports.

Traveling by train: Union Station is the closest Amtrak station to the hotel and meeting venue. From there, you can take the Red Line metro towards Shady Grove to Shady Grove Metro Station.

Traveling by car: Parking at the Shady Grove campus parking structure is free. When you enter, please take a ticket and have your parking validated by security before you leave.

Special Needs

The National Institutes of Health and the hotel are in compliance with requirements of the Americans with Disabilities Act (ADA). Please indicate any special needs on the registration form and we will make every effort to accommodate you.

Agenda

Day 1: Tuesday, September 24
Time	Session
8:30 – 9:00 a.m.	Welcome and Introduction Doug Lowy, M.D., Acting Director (National Cancer Institute) Janet Eary, M.D., Associate Director (Cancer Imaging Program, DCTD, National Cancer Institute) Piotr Grodzinski, Ph.D., Branch Chief (NSDB/CIP/DCTD, National Cancer Institute)
Session I	Moderator: Piotr Grodzinski, Ph.D. (National Cancer Institute)
9:00 – 9:35 a.m.	UCLA/Caltech/ISB Center Highlights and Takeaways James Heath, Ph.D. (Institute for Systems Biology)
9:35 – 10:10 a.m.	MSKCC-Cornell Center Highlights and Takeaways Michelle Bradbury, Ph.D, M.D. (Memorial Sloan Kettering Cancer Center)
10:10 – 10:30 a.m.	Break
10:30 – 11:15 a.m.	Keynote Presentation: Nanomedicine: past, present, and future Omid Farokhzad, M.D., M.B.A. (Brigham and Women’s Hospital)
11:15 a.m. – 12:00 p.m.	Keynote Presentation: Most pressing needs in cancer research and oncology in context of new technology development Phuoc Tran, M.D., Ph.D. (Johns Hopkins University)
12:00 – 1:15 p.m.	Lunch
Session II	Moderator: Christopher Hartshorn, Ph.D. (National Cancer Institute)
1:15 – 1:35 p.m.	Effective delivery of a therapeutic monoclonal antibody to metastases in the central nervous system of mice via polymer encapsulation and receptor targeting Masakazu Kamata, Ph.D. (UCLA)
1:35 – 1:55 p.m.	Novel approach to attenuate small lung cancer growth and metastasis Wasim Nasser, Ph.D. (University of Nebraska Medical Center)
1:55 – 2:15 p.m.	Wireless nano-optogenetic immunotherapy Gang Han, Ph.D. (University of Massachusetts Worchester)
2:15 – 2:45 p.m.	Imaging the delivery and action of nanomaterials in vivo: an update of MGH IRCN progress Miles Miller, Ph.D. (Massachusetts General Hospital)
2:45 – 3:15 p.m.	Break and Alliance Celebration
3:15 – 4:`35 p.m.	T32 Program Overviews Jianghong Rao, Ph.D. (Stanford University CNTC) Konstantin Sokolov, Ph.D. (The University of Texas MD Anderson CNTC) Alexander Stegh, Ph.D. (Northwestern University CNTC) Andrew Kummel, Ph.D. (University of California, San Diego CNTC) Alexander Kabanov, Ph.D. (The University of North Carolina at Chapel Hill CNTC)
5:15 – 6:15 p.m.	Coordination and Governance Committee Meeting (by invitation only) Rm. 2W910

Day 2: Wednesday, September 25
Time	Session
Session III	Moderator: Christopher Hartshorn, Ph.D. (National Cancer Institute)
9:00 – 9:35 a.m.	UNC Chapel Hill Center Highlights and Takeaways Leaf Huang, Ph.D. (University of North Carolina at Chapel Hill)
9:35 – 10:10 a.m.	WUSTL Center Highlights and Takeaways Sam Achilefu, Ph.D. (Washington University in St. Louis)
10:10 – 10:30 a.m.	Break
10:30 – 11:05 a.m.	Northwestern Center Highlights and Takeaways Chad Mirkin, Ph.D. (Northwestern University)
11:05 – 11:35 a.m.	Use of a Silicasome Nanoparticle platform for Treatment of Pancreatic Ductal Adenocarcinoma Huan Meng, Ph.D. (UCLA)
11:35 – 11:55 a.m.	Whitlockite Nanoparticle-based Immunotherapy for Bone Metastasis Shiladitya Sengupta, Ph.D. (Brigham and Women’s Hospital)
11:55 a.m. – 1:10 p.m.	Lunch
Session IV	Moderator: Luisa Russell, Ph.D. (National Cancer Institute)
1:10 – 1:30 p.m.	UNC Clinical/Scientific Highlight Talk Andrew Wang, M.D. (University of North Carolina at Chapel Hill)
1:30 – 1:50 p.m.	Northwestern Clinical/Scientific Highlight Talk – Spherical Nucleic Acid Nanotechnology for Cancer Immunotherapy: Advance to Clinical Evaluation and Rational Development of Vaccines Andrew Lee, Ph.D. (Northwestern University)
1:50 – 2:10 p.m.	WUSTL Clinical/Scientific Highlight Talk Gregory Lanza, M.D., Ph.D. (Washington University in St. Louis)
2:10 – 2:30 p.m.	Stanford Clinical/Scientific Highlight Talk Alice Fan, M.D. (Stanford University)
2:30 – 2:50 p.m.	MSKCC-Cornell Clinical/Scientific Highlight Talk Michelle Bradbury, Ph.D., M.D. (Memorial Sloan Kettering Cancer Center)
2:50 – 3:10 p.m.	UCLA/Caltech/ISB Clinical/Scientific Highlight Talk Wei Wei, Ph.D. (Institute for Systems Biology)
3:10 – 3:30 p.m.	Break
3:30 – 3:50 p.m.	Nanoparticles for the Treatment of Intraperitoneal Mesothelioma: Enhancing Tumor Localization and Increasing Drug-Loading for Improved Efficacy Mark Grinstaff, Ph.D. (Boston University)
3:50 – 4:20 p.m.	The Rodent Eye as a Non-invasive Window for Understanding Cancer Nanotherapeutics Kit Lam, Ph.D. (UC Davis)
4:20 – 4:40 p.m.	Folate-displaying exosome mediated cytosolic delivery of siRNA avoiding endosome trapping Peixuan Guo, Ph.D. (Ohio State)
4:40 – 5:00 p.m.	Alliance achievements by the numbers Piotr Grodzinski, Ph.D. (National Cancer Institute)
5:00 – 6:00 p.m.	Poster Session, 2nd Floor Atrium

Day 3, Thursday, September 26
Time	Session
Session V	Moderator: Christina Liu, Ph.D. P.E. (National Cancer Institute)
9:00 – 9:35 a.m.	Stanford Center Highlights and Takeaways Shan Wang, Ph.D. (Stanford University)
9:35 – 10:05 a.m.	Nanostructure-Embedded Microchips for Liquid Biopsy in Cancer Hsian Rong Tseng, Ph.D. (UCLA) Edwin Posadas, M.D. (Cedars-Sinai Medical Center)
10:05 – 10:25 a.m.	Break
10:25 – 10:55 a.m.	Targeted Core Shell Nanogels for Triple Negative Breast Cancer Alexander Kabanov, Ph.D. (University of North Carolina at Chapel Hill)
10:55 – 11:25 a.m.	Co-delivery of Targeted Stroma-breaking Theranostic Nanoparticle and Immune Checkpoint Nano-PD-L1 Inhibitor for the Treatment of Pancreatic Cancer Lily Yang, M.D., Ph.D. (Emory University)
11:25 – 11:55 a.m.	Nanoscale Metal-organic Frameworks for Light Triggered and X-ray Induced Photodynamic Therapy of Head and Neck Cancers Wenbin Lin, Ph.D. (University of Chicago)
11:55 p.m. – 12:25 p.m.	Delivery of drugs to brain tumors using multicomponent nanoparticles Efstathios Karathanasis, Ph.D. (Case Western Reserve University)
12:25 – 12:55 p.m.	Poster Prizes and Closing Comments Piotr Grodzinski, Ph.D. (National Cancer Institute)
1:00 p.m.	Adjournment

Abstract Information

Oral Presentation Abstracts

Deadline: September 6, 2019
If you have been invited to speak at the NCI Nano Alliance PI Meeting, please submit your abstract and biography.

Poster Abstract Submission

Deadline: September 6, 2019
You will be notified by September 11 as to whether your abstract has been accepted for poster presentation at the meeting.

It is requested that each award present poster(s) to disseminate the research associated with individual projects from over the last year. The posters should include and represent the projects funded by their Alliance-funded NCI grant. Poster examples include: progress by primary projects, pilot projects recently funded from NCI RFPs and their aims for the following year, pilot projects initiated by CCNEs from their original awards and leveraged funding, Core projects, trainee projects funded under the NCI Alliance awards, etc.

Posters should represent any of the above, and the total number is limited relative to award type as specified below. The presenters can be any trainee or investigator attached to the award whom will be attending the PI Meeting.

The project poster allotments for each award, are:

CCNE (U54): 4-6 posters
IRCN (U01): 1-2 posters
CNTC (T32): 3 posters

If you wish to present a poster at the NCI Nano Alliance PI Meeting, please submit your abstract and biography.