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Observational Cancer Research Studies

Here you can find selected observational studies currently enrolling participants.

Long-Term Cancer Prevention Study

This study is for people without a history of a cancer at the time of enrollment and a member of a partner healthcare system. Participants are asked to donate saliva and other samples and to answer health questions over time. Participants receive results from surveys and tests. To learn more and join, visit the Connect for Cancer Prevention website or contact the study team directly at (866) 462-6621 and by email at ConnectSTudy@norc.org.

Type: Observational
Ages: 45 - 65 at enrollment
Benefit: Survey and test results
Cost: Free
Duration: Years
Location: View all
Next Steps: Visit website

Brain and Spinal Cord Tumor Study

This study is for people with central nervous system (CNS) cancers. Participants are evaluated at the NIH Clinical Center in Bethesda, Maryland, asked to complete questionnaires, and donate tissue and blood samples for evaluation. Participants are connected to doctors for disease management and new treatment options. To learn more and join, visit the NCI-CONNECT website or contact the study team directly at (240) 760-6530 and by email at NCICONNECT@mail.nih.gov.

Type: Observational
Ages: 18 and up
Benefit: Referral to specialists
Cost: Free
Duration: One time 
Location: Bethesda, MD
Next Steps: Visit website

Childhood Cancer Molecular Testing Program

This study is for children, adolescents, and young adults newly diagnosed with certain cancers and receiving treatment at a Children's Oncology Group-affiliated hospital. Participants provide tumor tissue and blood samples for molecular testing. Test results can help patients and their doctors determine the best treatment options. To learn more, visit the CCDI Molecular Characterization Initiative.

Type: Observational
Ages: 25 and younger
Benefit: Free molecular testing
Cost: Free
Duration: One time
Location: View all
Next Steps: Visit website

Leiomyosarcoma Project

This study is for people with leiomyosarcoma who live in the United States or Canada. Participants are asked to share experiences living with the disease, provide access to medical records, give a saliva sample, and possibly donate tissue and blood samples. Participants can receive results from testing of samples, if desired. To learn more and join, visit the project website.

Type: Observational
Ages: All
Benefit: Results of samples tested
Cost: Free
Duration: Ongoing
Location: At home
Next Steps: Visit website

Low Grade Glioma Study

This study is for people with initial diagnosis of low grade glioma (astrocytoma, oligo-astrocytoma or mixed, oligodendroglioma) who have had two or more surgeries to treat it. Participants are asked to share medical tests, complete an online survey, and provide a saliva sample. To learn more, visit the study website.

Type: Observational
Ages: 21 -79
Benefit: Results of samples tested
Cost: Free
Duration: Annually for 4-5 years 
Location: At home
Next Steps: Visit website

Rare Solid Tumors Study

This study is for people with certain rare solid tumors. Family members may also join the study. Participants are asked to donate saliva, tumor tissue (when available), and sometimes blood, and to answer health questions over time. Genetic testing and counseling may be provided to suggest treatment for tumors. To learn more and join, visit the MyPART study website.

Type: Observational
Ages: All
Benefit: Free molecular testing and doctor referral
Cost: Free
Duration: Years
Location: At home or Bethesda, MD
Next Steps: Visit website

Osteosarcoma Project

This study is for people with osteosarcoma and their families in the United States or Canada. Participants are asked to share experiences living with the disease, provide access to medical records, donate a saliva sample, and possibly donate tissue and blood samples. Participants can receive results from testing of samples, if desired. To learn more and join, visit the project website.

Type: Observational
Ages: All
Benefit: Results of samples tested
Cost: Free
Duration: One time 
Location: At home
Next Steps: Visit website

Tumor Tissue and Blood Donation Study

This study is for people with certain cancers receiving standard treatments (not experimental) at a participating hospital. Participants are asked to donate tumor tissue, blood samples, and health information. Participants receive free tumor biomarker testing to help identify additional treatment options. To learn more and join, visit the Cancer MoonshotSM Biobank website.

Type: Observational
Ages: 13 and up
Benefit: Tumor biomarker testing
Cost: Free
Duration: Ongoing during treatment 
Location: View all
Next Steps: Visit website

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