Penile Cancer Treatment by Stage

Treatment of stage 0 may include:

• Mohs microsurgery
• topical chemotherapy
• topical immunotherapy with imiquimod
• laser surgery
• cryosurgery

If the cancer is only in the foreskin, wide local excision and circumcision may be the only treatment needed.

Treatment of stage I penile cancer may also include:

• surgery (partial or total penectomy with or without removal of lymph nodes in the groin)
• external or internal radiation therapy
• Mohs microsurgery

Treatment of stage II penile cancer may include:

• surgery (partial or total penectomy, with or without removal of lymph nodes in the groin)
• external or internal radiation therapy followed by surgery

Treatment of stage III penile cancer may include:

• surgery (penectomy and removal of lymph nodes in the groin) with or without radiation therapy
• radiation therapy

Treatment of stage IV penile cancer is usually palliative (to relieve symptoms and improve the quality of life).

Treatment may include:

• surgery (wide local excision and removal of lymph nodes in the groin)
• radiation therapy

Treatment of recurrent penile cancer may include:

• surgery (penectomy)
• radiation therapy