aromatase inhibitor

(uh-ROH-muh-tays in-HIH-bih-ter)
A drug that blocks the activity of an enzyme called aromatase, which the body uses to make estrogen in the ovaries and other tissues. Blocking aromatase lowers the amount of estrogen made by the body, which may stop the growth of cancer cells that need estrogen to grow. Aromatase inhibitors are used to treat some types of breast cancer or to keep it from coming back. They may also be used to help prevent breast cancer in some women who are at a high risk of developing it. Examples of aromatase inhibitors are anastrozole, letrozole, and exemestane. Aromatase inhibitors are a type of hormone therapy. Also called AI drug.