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exemestane
A synthetic androgen analogue. Exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the conversion of cholesterol to pregnenolone and the peripheral aromatization of androgenic precursors into estrogens. Check for
active clinical trials
or
closed clinical trials
using this agent. (
NCI Thesaurus
)
US brand name:
Aromasin
Abbreviation:
PNU 155971
Code name:
FCE-24304
Chemical structure name:
6-Methyleneandrosta-1,4-diene-3,17-dione
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