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rituximab
A recombinant chimeric murine/human antibody directed against the CD20 antigen, a hydrophobic transmembrane protein located on normal pre-B and mature B lymphocytes. Following binding, rituximab triggers a host cytotoxic immune response against CD20-positive cells. Check for
active clinical trials
or
closed clinical trials
using this agent. (
NCI Thesaurus
)
Synonyms:
C2B8 Monoclonal Antibody
IDEC-C2B8 monoclonal antibody
US brand name:
Rituxan
Foreign brand name:
Mabthera
Abbreviation:
MOAB IDEC-C2B8
Code names:
IDEC-102
IDEC-C2B8
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