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celecoxib
A nonsteroidal anti-inflammatory drug (NSAID) with a diaryl-substituted pyrazole structure. Celecoxib selectively inhibits cyclo-oxygenase-2 activity (COX-2); COX-2 inhibition may result in apoptosis and a reduction in tumor angiogenesis and metastasis. Check for
active clinical trials
or
closed clinical trials
using this agent. (
NCI Thesaurus
)
Synonym:
YM 177
US brand name:
Celebrex
Code name:
SC-58635
Chemical structure name:
4-(5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide
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