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bevacizumab
A recombinant humanized monoclonal antibody directed against the vascular endothelial growth factor (VEGF), a pro-angiogenic cytokine. Bevacizumab binds to VEGF and inhibits VEGF receptor binding, thereby preventing the growth and maintenance of tumor blood vessels. Check for
active clinical trials
or
closed clinical trials
using this agent. (
NCI Thesaurus
)
Synonyms:
anti-VEGF humanized monoclonal antibody
anti-VEGF monoclonal antibody
anti-VEGF rhuMAb
recombinant humanized anti-VEGF monoclonal antibody
rhuMAb VEGF
US brand name:
Avastin
Abbreviation:
rhuMab-VEGF