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NCI Dictionary of Cancer Terms

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NCI Dictionary of Cancer Terms



siplizumab  listen  (sip-LIH-zoo-mab)

  A substance being studied in the treatment of certain types of T-cell lymphoma. It is also being studied in the prevention of organ or tissue rejection after a kidney and/or bone marrow transplant. Siplizumab binds to a protein called CD2, which is found on some types of immune cells and cancer cells. This may help suppress the body’s immune response and it may help kill cancer cells. Siplizumab is a type of monoclonal antibody. Also called MEDI-507.