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NCI Dictionary of Cancer Terms

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NCI Dictionary of Cancer Terms



phase II detoxification  listen  (fayz ... dee-TOK-sih-fih-KAY-shun)

  A process in which the liver uses one of two major enzyme pathways to change a toxic substance, such as an anticancer drug, into a less toxic substance that is easier for the body to excrete. In phase II detoxification, liver cells add a substance (such as cysteine, glycine, or a sulfur molecule) to a toxic chemical or drug, to make it less harmful.