NCI Dictionary of Cancer Terms
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A growth on the surface of the cervix with moderately or severely abnormal cells. HSILs are usually caused by certain types of human papillomavirus (HPV) and are found when a Pap test is done. If not treated, these abnormal cells may become cancer and spread to nearby normal tissue. A HSIL is sometimes called moderate or severe dysplasia. Also called high-grade squamous intraepithelial lesion.