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NCI Dictionary of Cancer Terms


HMG-CoA reductase inhibitor  listen  (HMG-koh-A ree-DUK-tays in-HIH-bih-ter)

  A substance that blocks an enzyme needed by the body to make cholesterol and lowers the amount of cholesterol in the blood. HMG-CoA reductase inhibitor drugs are called statins. Also called hydroxymethylglutaryl-coenzyme A reductase inhibitor.