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NCI Dictionary of Cancer Terms

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NCI Dictionary of Cancer Terms



Hodgkin disease  listen  (HOJ-kin dih-ZEEZ)

  A cancer of the immune system that is marked by the presence of a type of cell called the Reed-Sternberg cell. The two major types of Hodgkin disease are classical Hodgkin lymphoma and nodular lymphocyte-predominant Hodgkin lymphoma. Symptoms include the painless enlargement of lymph nodes, spleen, or other immune tissue. Other symptoms include fever, weight loss, fatigue, or night sweats. Also called Hodgkin lymphoma.

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Reed-Sternberg cell; photograph shows normal lymphocytes compared with a Reed-Sternberg cell.