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NCI Dictionary of Cancer Terms

tirapazamine  listen  (TEER-uh-PA-zuh-meen)

  A substance that has been studied in the treatment of some types of cancer. It may cause damage to the DNA in cells that have a low level of oxygen, including cancer cells. This may make the cells easier to kill with radiation therapy and chemotherapy. Tirapazamine is a type of radiosensitizing agent and a type of chemosensitizing agent.