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NCI Dictionary of Cancer Terms

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NCI Dictionary of Cancer Terms



90Y-DOTA-biotin  listen  (… BY-oh-tin)

  A compound that contains the radioisotope yttrium Y 90 linked to the chemical biotin. Biotin is a molecule that binds strongly to the chemical streptavidin. 90Y-DOTA-biotin will find tumor cells in the body that have been targeted by an antibody linked to streptavidin and kill them. It is being studied together with CC49-streptavidin in the treatment of cancer. Also called yttrium Y 90 DOTA-biotin.