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NCI Dictionary of Cancer Terms


yttrium Y 90 ibritumomab tiuxetan  listen  (IH-tree-um ... ih-brih-TOO-moh-mab ty-UK-seh-tan)

  A drug used with the drug rituximab to treat certain types of B-cell non-Hodgkin lymphoma. It is also being studied in the treatment of other types of B-cell tumors. Yttrium Y 90 ibritumomab tiuxetan contains a monoclonal antibody that binds to a protein called CD20, which is found on B cells. It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 ibritumomab tiuxetan is a type of radioimmunoconjugate. Also called IDEC-Y2B8, Y 90 ibritumomab tiuxetan, and Y 90 Zevalin.