NCI Dictionary of Cancer Terms
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stage IV malignant mesothelioma (...muh-LIG-nunt MEH-zoh-THEE-lee-OH-muh)
Cancer cannot be removed by surgery and is found in one or both sides of the body. Cancer may have spread to lymph nodes anywhere in the chest or above the collarbone. Cancer has spread in one or more of the following ways: (1) through the diaphragm into the peritoneum (the thin layer of tissue that lines the abdomen and covers most of the organs in the abdomen); (2) to the tissue lining the chest on the opposite side of the body as the tumor; (3) to the chest wall and may be found in the rib; (4) into the organs in the center of the chest cavity; (5) into the spine; (6) into the sac around the heart or into the heart muscle; and/or (7) to distant parts of the body such as the brain, spine, thyroid, or prostate.