NCI Dictionary of Cancer Terms
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A drug used to treat peripheral T-cell lymphoma that has come back or has not gotten better with other treatment. It is also being studied in the treatment of other types of cancer. PXD101 blocks certain enzymes needed for cell division and may kill cancer cells. It may also prevent the growth of new blood vessels that tumors need to grow and may help make cancer cells easier to kill with other anticancer drugs. It is a type of histone deacetylase (HDAC) inhibitor, a type of angiogenesis inhibitor, and a type of chemosensitizer. Also called Beleodaq and belinostat.