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NCI Dictionary of Cancer Terms


yttrium Y 90 DOTA monoclonal antibody HuPAM4  listen  (IH-tree-um ... MAH-noh-KLOH-nul AN-tee-BAH-dee ...)

  A substance being studied in the treatment of advanced pancreatic cancer. Yttrium Y 90 DOTA monoclonal antibody HuPAM4 contains a monoclonal antibody that binds to a protein called MUC-1, which is found on some pancreatic cancer cells. It also contains a radioactive substance called yttrium Y 90, which may help kill cancer cells. Yttrium Y 90 DOTA monoclonal antibody HuPAM4 is a type of radioimmunoconjugate. Also called yttrium Y 90 clivatuzumab tetraxetan.