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NCI Dictionary of Cancer Terms

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NCI Dictionary of Cancer Terms



EGFR tyrosine kinase inhibitor  listen  (... TY-ruh-seen KY-nays in-HIH-bih-ter)

  A substance that blocks the activity of a protein called epidermal growth factor receptor (EGFR). EGFR is found on the surface of some normal cells and is involved in cell growth. It may also be found at high levels on some types of cancer cells, which causes these cells to grow and divide. Blocking EGFR may keep cancer cells from growing. Some EGFR tyrosine kinase inhibitors are used to treat cancer. Also called EGFR inhibitor, epidermal growth factor receptor inhibitor, and epidermal growth factor receptor tyrosine kinase inhibitor.