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NCI Dictionary of Cancer Terms

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NCI Dictionary of Cancer Terms



maytansinoid DM4-conjugated humanized monoclonal antibody huC242  listen  (may-TAN-sih-noyd DM4-KON-juh-GAY-ted HYOO-muh-nized MAH-noh-KLOH-nul AN-tee-BAH-dee...)

  A substance being studied in the treatment of some types of cancer. It is made by linking the monoclonal antibody huC242 to a toxic substance called maytansinoid DM4. The monoclonal antibody binds to the surfaces of cancer cells and the maytansinoid DM4 enters the cells and blocks their growth. It is a type of immunotoxin. Also called huC242-DM4.