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NCI Dictionary of Cancer Terms


nodular lymphocyte-predominant Hodgkin lymphoma  listen  (NAH-juh-ler LIM-foh-site-preh-DAH-mih-nunt HOJ-kin lim-FOH-muh)

  A rare type of Hodgkin lymphoma (a cancer of the immune system). It is marked by the presence of lymphocyte-predominant cells, which used to be called popcorn cells. These cells are different from the typical Reed-Sternberg cells found in classical Hodgkin lymphoma. Nodular lymphocyte-predominant Hodgkin lymphoma may change into diffuse large B-cell lymphoma. Also called LPHL, lymphocyte-predominant Hodgkin lymphoma, and NLPHL.