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NCI Dictionary of Cancer Terms


yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A  listen  (IH-tree-um … MAH-noh-KLOH-nul AN-tee-BAH-dee …)

  A substance being studied in the treatment of some types of cancer. M5A is a monoclonal antibody that binds to a protein called CEA on the surface of some tumor cells. It is linked to a radioisotope called yttrium Y 90, which may help kill the cancer cells. Yttrium Y 90 DOTA anti-CEA monoclonal antibody M5A is a type of radioimmunoconjugate and a type of radiopharmaceutical.