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NCI Dictionary of Cancer Terms


EZN-2285   

  A drug used to treat acute lymphoblastic leukemia (ALL). It is a form of the anticancer drug PEG-asparaginase that stays in the body longer. EZN-2285 is an enzyme that breaks down the amino acid asparagine and may block the growth of tumor cells that need asparagine to grow. It is a type of protein synthesis inhibitor. Also called Oncaspar-IV and SC-PEG E. coli L-asparaginase.