Español
Questions About Cancer? 1-800-4-CANCER
  • Print
  • Facebook
  • Twitter
  • Google+
  • Pinterest

NCI Dictionary of Cancer Terms


stage I esophageal adenocarcinoma  listen  (... ee-SAH-fuh-JEE-ul A-deh-noh-KAR-sih-NOH-muh)

  Stage I is divided into stages IA and IB, depending on where the cancer is found. In stage IA, cancer has formed in the mucosa or submucosa layer of the esophagus wall. The cancer cells are grade 1 or 2. Grade 1 and 2 cancer cells look more like normal cells under a microscope and grow and spread more slowly than grade 3 cancer cells. In stage IB, cancer has formed (1) in the mucosa or submucosa layer of the esophagus wall, and the cancer cells are grade 3. Grade 3 cancer cells look more abnormal under a microscope and grow and spread more quickly than grade 1 and 2 cancer cells; or (2) in the mucosa or submucosa layer and spread into the muscle layer of the esophagus wall, and the cancer cells are grade 1 or 2.

Enlarge
Stage IA adenocarcinoma of the esophagus; drawing shows the esophagus and stomach. An inset shows cancer cells in the mucosa and submucosa layers of the esophagus wall. Also shown are the muscle and connective tissue layers of the esophagus wall and lymph nodes.
Enlarge
Stage IB adenocarcinoma of the esophagus; drawing shows the esophagus and stomach. A two-panel inset shows the layers of the esophagus wall: the mucosa, submucosa, muscle, and connective tissue layers. Also shown are lymph nodes. The left panel shows cancer in the mucosa and submucosa layers. The right panel shows cancer in the mucosa, submucosa, and muscle layers.