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NCI Dictionary of Cancer Terms


PPAR gamma pathway  listen  (… GA-muh PATH-way)

  Describes a group of proteins in a cell that work together to help control how certain genes are expressed and the use of lipids (fats) and glucose (sugar) in the body. Changes in the PPAR gamma pathway may lead to diseases such as heart disease, diabetes, and cancer. Drugs or substances that affect this pathway are being studied in the prevention and treatment of cancer and other diseases. Also called peroxisome proliferator-activated receptor gamma pathway.