NCI Dictionary of Cancer Terms
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A drug used to treat non-small cell lung cancer that has spread to other parts of the body and has a mutated (changed) form of a gene called anaplastic lymphoma kinase (ALK). It is used in patients whose cancer has gotten worse after treatment with or who cannot receive certain anticancer drugs. Zykadia blocks the protein made by the mutated ALK gene. Blocking this protein may stop the growth and spread of cancer cells. Zykadia is a type of tyrosine kinase inhibitor. Also called ceritinib.