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A vaccine formulation consisting of recombinant vaccinia virus encoding prostate specific antigen (PSA) and recombinant vaccinia virus encoding three co-stimulatory molecule transgenes B7.1, ICAM-1, and LFA-3 (TRICOM). Vaccination with PSA in combination with TRICOM may enhance antigen presentation, resulting in the augmentation of a cytotoxic T cell (CTL) immune response against tumor cells expressing PSA. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
recombinant vaccinia-PSA(L155)/TRICOM vaccine
vaccinia-prostate-specific antigen-TRICOM vaccine