NCI Drug Dictionary
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A synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol. Ursodiol also reduces the absorption of cholesterol from the intestinal tract. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand names:||Actigall |
|Foreign brand name:||Deursil|
|Chemical structure:||(3alpha,5beta,7beta)-3,7-Dihydroxycholan-24-oic acid|