NCI Drug Dictionary
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A semisynthetic ansamycin antibiotic with potent antimycobacterial properties. Rifabutin inhibits bacterial DNA-dependent RNA polymerase, thereby suppressing the initiation of RNA formation and leading to inhibition of RNA synthesis and transcription. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
|US brand name:||Mycobutin|