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NCI Drug Dictionary

  

tacedinaline 
An orally bioavailable substituted benzamide derivative with potential antineoplastic activity. Tacedinaline inhibits histone deacetylation, which may result in histone hyperacetylation, followed by the induction of differentiation, the inhibition of cell proliferation, and apoptosis in susceptible tumor cell populations. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:acetyldinaline
Code name:CI-994
Chemical structure:4-acetamido-N-(2-aminophenyl)benzamide