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NCI Drug Dictionary


recombinant fowlpox-CEA(6D)/TRICOM vaccine 
A cancer vaccine comprised of a recombinant fowlpox virus vector encoding the carcinoembryonic antigen (CEA) and a TRIad of COstimulatory Molecules (B7-1, ICAM-1 and LFA-3) (TRICOM). This agent may enhance CEA presentation to antigen presenting cells (APC) and activate cytotoxic T-cells against CEA-expressing tumors. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)