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NCI Drug Dictionary


recombinant tyrosinase-related protein-2 
A recombinant therapeutic agent which is chemically identical to or similar to an endogenous non-mutated melanocyte differentiation antigen expressed by both normal and malignant melanocytes. Vaccinations with recombinant tyrosinase-related protein-2 may elicit an antitumoral cytotoxic T-cell response against tumor cells and some normal cells that express tyrosinase-related protein-2. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:Tyrosinase-Related Protein-2