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NCI Drug Dictionary

NCI Drug Dictionary

  

monoclonal antibody 105AD7 anti-idiotype vaccine 
A cancer vaccine consisting of a humanized monoclonal antibody that mimics a tumor-associated antigen 791Tgp72 (also known as CD55). Vaccination with this agent may stimulate a host cytotoxic T-cell response against tumor cells expressing CD55, resulting in tumor cell lysis. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:105AD7
Abbreviation:MOAB 105AD7