Español
Questions About Cancer? 1-800-4-CANCER
  • Print
  • Facebook
  • Twitter
  • Google+
  • Pinterest

NCI Drug Dictionary

  

ipilimumab  Patient Information
A monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen-4 (CTLA4), an antigen that is expressed on activated T-cells and exhibits affinity for B7 co-stimulatory molecules. By binding CTLA4, ipilimumab enhances T-cell activation and blocks B7-1 and B7-2 T-cell co-stimulatory pathways. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:anti-cytotoxic T-lymphocyte-associated antigen-4 monoclonal antibody
MOAB CTLA-4
monoclonal antibody CTLA-4
US brand name:Yervoy
Abbreviation:MDX-CTLA-4
Code names:BMS-734016
MDX-010