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NCI Drug Dictionary

  

apolizumab 
A humanized monoclonal antibody directed against 1D10, a polymorphic determinant on the HLA-DR beta chain that is expressed on normal and neoplastic B cells. Apolizumab induces complement-mediated cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and apoptosis of 1D10 antigen-positive B cells in vitro. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonyms:1D1O Anti-lymphoma Antibody
Monoclonal antibody 1D10
Monoclonal Antibody Hu1D10
US brand name:Remitogen
Abbreviations:MOAB 1D10
MoAb Hu1D10