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NCI Drug Dictionary

  

imiquimod  Patient Information
A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
US brand name:Aldara
Abbreviation:IMQ
Code names:R 837
S 26308
Chemical structures:1H-Imidazo(4,5-c)quinolin-4-amine, 1-(2-methylpropyl)-
4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline