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NCI Drug Dictionary

  

lenalidomide  Patient Information
A thalidomide analog with potential antineoplastic activity. Lenalidomide inhibits TNF-alpha production, stimulates T cells, reduces serum levels of the cytokines vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), and inhibits angiogenesis. This agent also promotes G1 cell cycle arrest and apoptosis of malignant cells. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus)
Synonym:IMiD-1
US brand name:Revlimid
Code name:CC-5013